Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Smarca4provided by RGD
Official Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4provided by RGD
Primary source: RGD:621728
See related: Ensembl:ENSRNOG00000009271 AllianceGenome:RGD:621728
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: brg-1
Summary: Enables chromatin binding activity. Involved in negative regulation of transcription, DNA-templated; nucleosome disassembly; and spermatid development. Located in nucleus. Part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid cancer. Orthologous to human SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Thymus (RPKM 391.9), Adrenal (RPKM 353.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q13

Exon count:: 37

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (28438370..28535071)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (20167717..20258975)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (22648323..22739468)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

T3 Critically Affects the Mhrt/Brg1 Axis to Regulate the Cardiac MHC Switch: Role of an Epigenetic Cross-Talk.
Title: T3 Critically Affects the Mhrt/Brg1 Axis to Regulate the Cardiac MHC Switch: Role of an Epigenetic Cross-Talk.
Upregulation of heme oxygenase-1 by Brahma-related gene 1 through Nrf2 signaling confers protective effect against high glucose-induced oxidative damage of retinal ganglion cells.
Title: Upregulation of heme oxygenase-1 by Brahma-related gene 1 through Nrf2 signaling confers protective effect against high glucose-induced oxidative damage of retinal ganglion cells.
Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin selfadministration in rats.
Title: Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats.
Study using calcific rat aorta model of vascular smooth muscle cells stimulated with beta-glycerophosphate demonstrates that Smarca4 is involved in hyperphosphorus-induced vascular calcification.
Title: Label-free quantitative proteomics identifies Smarca4 is involved in vascular calcification.
BRG1 is a key mediator of the SMAD3-dependent regulation of cellular and behavioral plasticity that mediates cocaine seeking after a period of withdrawal.
Title: BRG1 in the Nucleus Accumbens Regulates Cocaine-Seeking Behavior.
Activation of DPF3a upon hypertrophic stimuli in cardiac hypertrophy switches cardiac fetal gene expression from being silenced by HEY to being activated by BRG1.
Title: Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.
MITF interacts with BRG1 to promote GATA4 expression in cardiac hypertrophy.
Title: MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy.
Results identify LRRFIP1, SMARCA4, and DNMT1 as novel regulators of macrophage multinucleation.
Title: Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation.
The activation of PPARg also inhibited the proliferation and collagen production of cardiac fibroblasts, and down-regulated the activity of Brg1 and the expression of TGF-b1
Title: Activation of peroxisome proliferator-activated receptor γ (PPARγ) through NF-κB/Brg1 and TGF-β1 pathways attenuates cardiac remodeling in pressure-overloaded rat hearts.
Speculate that changes in hippocampal Brg1 expression mediate glucocorticoid receptor expression and subsequently trigger neuroendocrine reprogramming in male IUGR rats.
Title: IUGR increases chromatin-remodeling factor Brg1 expression and binding to GR exon 1.7 promoter in newborn male rat hippocampus.

Submit: New GeneRIF Correction See all GeneRIFs (11)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI111450 (e-PCR)
- UniSTS:245028

Smarca4 (e-PCR), detects polymorphism
- UniSTS:516567

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	ISO Inferred from Sequence Orthology more info
enables ATP-dependent activity, acting on DNA	IBA Inferred from Biological aspect of Ancestor more info
enables ATP-dependent activity, acting on DNA	ISO Inferred from Sequence Orthology more info
enables ATP-dependent chromatin remodeler activity	IEA Inferred from Electronic Annotation more info
enables ATP-dependent chromatin remodeler activity	ISO Inferred from Sequence Orthology more info
enables DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables DNA polymerase binding	IEA Inferred from Electronic Annotation more info
enables DNA polymerase binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase I core promoter sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
contributes_to RNA polymerase I core promoter sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables Tat protein binding	IEA Inferred from Electronic Annotation more info
enables Tat protein binding	ISO Inferred from Sequence Orthology more info
enables chromatin binding	IDA Inferred from Direct Assay more info	PubMed
enables chromatin binding	ISO Inferred from Sequence Orthology more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables histone binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables lncRNA binding	ISO Inferred from Sequence Orthology more info
enables lysine-acetylated histone binding	IEA Inferred from Electronic Annotation more info
enables lysine-acetylated histone binding	ISO Inferred from Sequence Orthology more info
enables nuclear androgen receptor binding	IEA Inferred from Electronic Annotation more info
enables nuclear androgen receptor binding	ISO Inferred from Sequence Orthology more info
enables p53 binding	IEA Inferred from Electronic Annotation more info
enables p53 binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-containing complex binding	IDA Inferred from Direct Assay more info	PubMed
enables transcription coactivator activity	IEA Inferred from Electronic Annotation more info
enables transcription coactivator activity	ISO Inferred from Sequence Orthology more info
enables transcription coregulator binding	IEA Inferred from Electronic Annotation more info
enables transcription coregulator binding	ISO Inferred from Sequence Orthology more info
enables transcription corepressor activity	IEA Inferred from Electronic Annotation more info
enables transcription corepressor activity	ISO Inferred from Sequence Orthology more info
enables transcription corepressor activity	ISS Inferred from Sequence or Structural Similarity more info
enables transcription factor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA methylation-dependent heterochromatin formation	ISO Inferred from Sequence Orthology more info
involved_in RNA polymerase I preinitiation complex assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within aorta development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within aortic smooth muscle cell differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within blastocyst growth	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within blastocyst hatching	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within blood vessel development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within cell morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in chromatin remodeling	IDA Inferred from Direct Assay more info	PubMed
involved_in chromatin remodeling	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chromatin remodeling	ISO Inferred from Sequence Orthology more info
involved_in chromatin remodeling	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within coronary vasculature development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within definitive erythrocyte differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within embryonic hindlimb morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within embryonic organ morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within epidermis morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within extracellular matrix organization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within forebrain development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within_negative_effect gene expression	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within glial cell fate determination	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within heart development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within heart trabecula formation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within hindbrain development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within in utero embryonic development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within keratinocyte differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within lens fiber cell development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within liver development	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of DNA-templated transcription	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of androgen receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of androgen receptor signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of cell growth	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of cell growth	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in nervous system development	ISO Inferred from Sequence Orthology more info
involved_in neural retina development	IEA Inferred from Electronic Annotation more info
involved_in neural retina development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within neurogenesis	ISO Inferred from Sequence Orthology more info
involved_in nucleosome disassembly	IDA Inferred from Direct Assay more info	PubMed
involved_in nucleosome disassembly	IEA Inferred from Electronic Annotation more info
involved_in nucleosome disassembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within outflow tract morphogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within pharyngeal arch artery morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation by host of viral transcription	IEA Inferred from Electronic Annotation more info
involved_in positive regulation by host of viral transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of Wnt signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of cell differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of cell population proliferation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cold-induced thermogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of glucose mediated signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of glucose mediated signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of miRNA transcription	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of miRNA transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within primitive erythrocyte differentiation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of cell migration	ISO Inferred from Sequence Orthology more info
involved_in spermatid development	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within stem cell population maintenance	ISO Inferred from Sequence Orthology more info
acts_upstream_of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in transcription initiation-coupled chromatin remodeling	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within vasculogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within ventricular septum development	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of SWI/SNF complex	IDA Inferred from Direct Assay more info	PubMed
part_of SWI/SNF complex	IEA Inferred from Electronic Annotation more info
part_of SWI/SNF complex	ISO Inferred from Sequence Orthology more info
part_of chromatin	ISO Inferred from Sequence Orthology more info
part_of euchromatin	ISO Inferred from Sequence Orthology more info
located_in fibrillar center	IEA Inferred from Electronic Annotation more info
located_in fibrillar center	ISO Inferred from Sequence Orthology more info
part_of heterochromatin	ISO Inferred from Sequence Orthology more info
located_in male germ cell nucleus	ISO Inferred from Sequence Orthology more info
part_of nBAF complex	ISO Inferred from Sequence Orthology more info
part_of nBAF complex	ISS Inferred from Sequence or Structural Similarity more info
part_of npBAF complex	IEA Inferred from Electronic Annotation more info
part_of npBAF complex	ISO Inferred from Sequence Orthology more info
part_of npBAF complex	ISS Inferred from Sequence or Structural Similarity more info
NOT located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	TAS Traceable Author Statement more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in perichromatin fibrils	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: transcription activator BRG1

Names: ATP-dependent helicase SMARCA4; BAF190A; BRG1-associated factor 190A; SNF2-beta; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; protein brahma homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_134368.1 → NP_599195.1 transcription activator BRG1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/Swiss-Prot

Q8K1P7

Related

ENSRNOP00000081001.1, ENSRNOT00000097065.1

Conserved Domains (9) summary

cd05516
Location:1425 → 1530

Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...

smart00592
Location:612 → 656

BRK; domain in transcription and CHROMO domain helicases

smart00573
Location:460 → 532

HSA; domain in helicases and associated with SANT domains

cd00046
Location:774 → 913

DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.

pfam08430
Location:43 → 164

Forkhead_N; Forkhead N-terminal region

pfam00176
Location:757 → 1052

SNF2_N; SNF2 family N-terminal domain

pfam00271
Location:1079 → 1194

Helicase_C; Helicase conserved C-terminal domain

pfam08880
Location:171 → 205

QLQ; QLQ

pfam14619
Location:1289 → 1356

SnAC; Snf2-ATP coupling, chromatin remodelling complex

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

28438370..28535071

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006242598.4 → XP_006242660.1 transcription activator BRG1 isoform X3

See identical proteins and their annotated locations for XP_006242660.1

UniProtKB/Swiss-Prot

Q8K1P7

UniProtKB/TrEMBL

A6JNT8, G3V790

Related

ENSRNOP00000013166.7

Conserved Domains (9) summary

cd05516
Location:1458 → 1564

Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...

smart00573
Location:460 → 532

HSA; domain in helicases and associated with SANT domains

PLN03142
Location:750 → 1232

PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional

COG1196
Location:370 → 570

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

pfam09606
Location:42 → 217

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal

cd18062
Location:731 → 981

DEXHc_SMARCA4; DEXH-box helicase domain of SMARCA4

pfam07533
Location:612 → 654

BRK; BRK domain

pfam08880
Location:171 → 205

QLQ

pfam14619
Location:1323 → 1389

SnAC; Snf2-ATP coupling, chromatin remodelling complex
XM_006242599.4 → XP_006242661.1 transcription activator BRG1 isoform X4

UniProtKB/Swiss-Prot

Q8K1P7

Conserved Domains (9) summary

cd05516
Location:1458 → 1563

Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...

smart00592
Location:612 → 656

BRK; domain in transcription and CHROMO domain helicases

smart00573
Location:460 → 532

HSA; domain in helicases and associated with SANT domains

cd00046
Location:774 → 913

DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.

pfam08430
Location:43 → 164

Forkhead_N; Forkhead N-terminal region

pfam00176
Location:757 → 1052

SNF2_N; SNF2 family N-terminal domain

pfam00271
Location:1079 → 1194

Helicase_C; Helicase conserved C-terminal domain

pfam08880
Location:171 → 205

QLQ; QLQ

pfam14619
Location:1322 → 1389

SnAC; Snf2-ATP coupling, chromatin remodelling complex
XM_063264830.1 → XP_063120900.1 transcription activator BRG1 isoform X1
XM_063264832.1 → XP_063120902.1 transcription activator BRG1 isoform X2
XM_006242601.4 → XP_006242663.1 transcription activator BRG1 isoform X7

See identical proteins and their annotated locations for XP_006242663.1

UniProtKB/Swiss-Prot

Q8K1P7

UniProtKB/TrEMBL

A6JNT9

Conserved Domains (9) summary

cd05516
Location:1425 → 1531

Bromo_SNF2L2; Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone ...

smart00592
Location:612 → 656

BRK; domain in transcription and CHROMO domain helicases

smart00573
Location:460 → 532

HSA; domain in helicases and associated with SANT domains

cd00046
Location:774 → 913

DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.

pfam08430
Location:43 → 164

Forkhead_N; Forkhead N-terminal region

pfam00176
Location:757 → 1052

SNF2_N; SNF2 family N-terminal domain

pfam00271
Location:1079 → 1194

Helicase_C; Helicase conserved C-terminal domain

pfam08880
Location:171 → 205

QLQ; QLQ

pfam14619
Location:1289 → 1356

SnAC; Snf2-ATP coupling, chromatin remodelling complex
XM_063264833.1 → XP_063120903.1 transcription activator BRG1 isoform X5
XM_063264834.1 → XP_063120904.1 transcription activator BRG1 isoform X6
XM_063264835.1 → XP_063120905.1 transcription activator BRG1 isoform X1
XM_063264836.1 → XP_063120906.1 transcription activator BRG1 isoform X1
XM_063264831.1 → XP_063120901.1 transcription activator BRG1 isoform X1