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AP2B1 adaptor related protein complex 2 subunit beta 1 [ Homo sapiens (human) ]

Gene ID: 163, updated on 7-Apr-2024

Summary

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Official Symbol
AP2B1provided by HGNC
Official Full Name
adaptor related protein complex 2 subunit beta 1provided by HGNC
Primary source
HGNC:HGNC:563
See related
Ensembl:ENSG00000006125 MIM:601025; AllianceGenome:HGNC:563
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ADTB2; AP105B; CLAPB1; AP2-BETA
Summary
The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in brain (RPKM 64.4), testis (RPKM 50.1) and 25 other tissues See more
Orthologs
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Genomic context

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Location:
17q12
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (35587322..35726413)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (36535193..36674326)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (33914341..34053432)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:33904854-33905669 Neighboring gene small nucleolar RNA host gene 30 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12077 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr17:33914287-33915486 Neighboring gene small nucleolar RNA, C/D box 7 Neighboring gene peroxisomal biogenesis factor 12 Neighboring gene transmembrane protein 160 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr17:33957282-33958481 Neighboring gene MPRA-validated peak2820 silencer Neighboring gene Sharpr-MPRA regulatory region 1039 Neighboring gene ribosomal protein L17 pseudogene 42 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8440 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:34059551-34060074 Neighboring gene RAS like family 10 member B Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12079 Neighboring gene growth arrest specific 2 like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. Paing MM, et al. Mol Cell Biol, 2006 Apr. PMID 16581796, Free PMC Article
  2. Expression of a novel beta adaptin subunit mRNA splice variant in human testes. Zhang XD, et al. Asian J Androl, 2005 Jun. PMID 15897975
  3. The structure and function of the beta 2-adaptin appendage domain. Owen DJ, et al. EMBO J, 2000 Aug 15. PMID 10944104, Free PMC Article
  4. Prevalence of Polymorphism and Post-Training Expression of ACTN3 (R/X) and ACE (I/D) Genes in CrossFit Athletes. Peña-Vázquez O, et al. Int J Environ Res Public Health, 2023 Mar 1. PMID 36901413, Free PMC Article
  5. AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition. Yang L, et al. Theranostics, 2018. PMID 30026878, Free PMC Article

See all (216) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Principal components analysis to evaluate complex association of polymorphisms in ACE and ACTN3 genes and the extent of cardiovascular adaptive changes in elite athletes.
    Title: Principal components analysis to evaluate complex association of polymorphisms in ACE and ACTN3 genes and the extent of cardiovascular adaptive changes in elite athletes.
  2. Polymorphisms of ACE and thrombophilic genes: risk for recurrent pregnancy loss.
    Title: Polymorphisms of ACE and thrombophilic genes: risk for recurrent pregnancy loss.
  3. Prevalence of Polymorphism and Post-Training Expression of ACTN3 (R/X) and ACE (I/D) Genes in CrossFit Athletes.
    Title: Prevalence of Polymorphism and Post-Training Expression of ACTN3 (R/X) and ACE (I/D) Genes in CrossFit Athletes.
  4. Reduced expression of AP-2beta was significantly associated with more advanced hepatocellular carcinoma stages and larger tumor sizes. The overexpression of AP-2beta reduced HCC proliferation, migration, invasion, tumor formation and metastasis in vitro and in vivo. Moreover, AP-2beta modulates the levels of epithelial-mesenchymal transition markers through Slug and Snail in hepatocellular carcinoma cell lines and tiss...
    Title: AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition.
  5. AP2B1 might be associated with the development of nonsyndromic cleft lip with or without cleft palate.
    Title: Associations of genetic variants in endocytic trafficking of epidermal growth factor receptor super pathway with risk of nonsyndromic cleft lip with or without cleft palate.
  6. this study determined a structure of AP2 that includes the clathrin-binding beta2 hinge.
    Title: Clathrin adaptors. AP2 controls clathrin polymerization with a membrane-activated switch.
  7. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
    Title: Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
  8. Results suggest that autosomal recessive hypercholesterolemia (ARH) and beta-arrestin depend on a privileged AP2beta2 appendage site for proper cargo recruitment to clathrin bud sites.
    Title: The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.
  9. multiple interactions between PIPKI gamma-p90 and AP-2 lead to spatiotemporally controlled PI(4,5)P(2) synthesis during clathrin-mediated synaptic vesicle endocytosis
    Title: Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
  10. EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics.
    Title: Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics.
Submit: New GeneRIF Correction See all GeneRIFs (14)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
New gene functions in megakaryopoiesis and platelet formation.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
Envelope transmembrane glycoprotein gp41 env HIV-1 Env gp41 requires the conserved membrane-proximal AP2B1 binding site in the gp41 cytoplasmic tail to evade antibody-dependent cell-mediated cytotoxicity (ADCC) via membrane-proximal endocytosis PubMed
env Two independent motifs, a membrane proximal conserved GYxxO motif (residues 711-715) and a C-terminal dileucine motif (residues 855-856), of the HIV-1 gp41 protein mediate endocytosis through interaction with the clathrin adaptor AP-2 PubMed
env The cytoplasmic domain (residues 707-856) of HIV-1 gp41 interacts with whole clathrin-associated AP-1 and AP-2 adaptor complexes PubMed
Nef nef Clathrin and the clathrin-associated, plasma membrane-localized AP2 complexes are required for the HIV-1 Nef-mediated downregulation of CD4 PubMed
nef A dileucine-motif-containing segment of Nef binds directly to the beta subunit of the clathrin adaptor complexes AP-2, which are responsible for recruiting sorted proteins into clathrin coated pits PubMed
nef HIV-1 Nef co-localizes with the beta subunit of the adaptor protein complexes (AP-2) in human T cells; Nef residues 174-179 are required for the co-localization of Nef with the beta subunit PubMed
nef In cells expressing an HIV-1 Nef-green fluorescent protein (GFP) fusion, CD28 co-localizes with the AP-2 clathrin adaptor and Nef-GFP PubMed
Pr55(Gag) gag HIV-1 Gag binds to AP-2, and this binding is dependent on tyrosine residue 132 and valine residue 135 at the matrix-capsid junction in the Gag polyprotein PubMed
Tat tat Both HIV-1 Tat 47-59 and FITC-labeled Tat 47-59 peptides upregulate gene expression of adaptor-related protein complex 2, beta 1 subunit (AP2B1) in U-937 macrophages PubMed
tat HIV-1 Tat enters T cells by using clathrin/AP2-mediated endocytosis followed by low-pH-induced and Hsp90-assisted endosomal translocation, which leads to cell responses that are induced from the cytosol PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • DKFZp781K0743

Gene Ontology Provided by GOA

Function Evidence Code Pubs
contributes_to clathrin adaptor activity TAS
Traceable Author Statement
more info
 PubMed 
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables clathrin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables clathrin binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables clathrin binding TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signal sequence binding TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in aorta development IEA
Inferred from Electronic Annotation
more info
  
involved_in clathrin-dependent endocytosis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in clathrin-dependent endocytosis NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in clathrin-dependent endocytosis TAS
Traceable Author Statement
more info
 PubMed 
involved_in coronary vasculature development IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in kidney development IEA
Inferred from Electronic Annotation
more info
  
involved_in postsynaptic neurotransmitter receptor internalization NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in synaptic vesicle endocytosis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in synaptic vesicle endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ventricular septum development IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of AP-2 adaptor complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of AP-2 adaptor complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of AP-2 adaptor complex NAS
Non-traceable Author Statement
more info
 PubMed 
part_of AP-2 adaptor complex TAS
Traceable Author Statement
more info
 PubMed 
part_of clathrin adaptor complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in clathrin-coated endocytic vesicle NAS
Non-traceable Author Statement
more info
 PubMed 
located_in clathrin-coated endocytic vesicle membrane TAS
Traceable Author Statement
more info
  
located_in cytoplasmic side of plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in endocytic vesicle membrane TAS
Traceable Author Statement
more info
  
located_in endolysosome membrane TAS
Traceable Author Statement
more info
  
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
  
located_in membrane HDA PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
  
located_in presynapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AP-2 complex subunit beta
Names
adapter-related protein complex 2 beta subunit
adapter-related protein complex 2 subunit beta
adaptin, beta 2 (beta)
adaptor protein complex AP-2 subunit beta
adaptor related protein complex 2 beta 1 subunit
adaptor-related protein complex 2 subunit beta
beta-2-adaptin
beta-adaptin
beta2-adaptin
clathrin assembly protein complex 2 beta large chain
clathrin-associated/assembly/adaptor protein, large, beta 1
plasma membrane adaptor HA2/AP2 adaptin beta subunit
testicular tissue protein Li 22

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030006.2 → NP_001025177.1  AP-2 complex subunit beta isoform a

    See identical proteins and their annotated locations for NP_001025177.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AI691147, BC006201, BC012150, BQ421703, BX643620, M34175
    Consensus CDS
    CCDS32621.1
    UniProtKB/TrEMBL
    A0A140VJE8, A8K0G3
    Related
    ENSP00000483185.1, ENST00000610402.5
    Conserved Domains (4) summary
    smart00809
    Location:731 → 831
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:840 → 950
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  2. NM_001282.3 → NP_001273.1  AP-2 complex subunit beta isoform b

    See identical proteins and their annotated locations for NP_001273.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AI691147, BQ421703, BX643620, M34175
    Consensus CDS
    CCDS32622.1
    UniProtKB/Swiss-Prot
    A6NJP3, P21851, P63010, Q7Z451, Q96J19
    UniProtKB/TrEMBL
    A8K0G3
    Related
    ENSP00000482315.1, ENST00000621914.4
    Conserved Domains (4) summary
    smart00809
    Location:717 → 817
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:826 → 936
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    35587322..35726413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524450.3 → XP_011522752.1  AP-2 complex subunit beta isoform X1

    See identical proteins and their annotated locations for XP_011522752.1

    UniProtKB/TrEMBL
    A8K0G3
    Conserved Domains (4) summary
    smart00809
    Location:731 → 825
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:872 → 982
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  2. XM_005257938.4 → XP_005257995.1  AP-2 complex subunit beta isoform X3

    See identical proteins and their annotated locations for XP_005257995.1

    UniProtKB/TrEMBL
    A0A140VJE8, A8K0G3
    Related
    ENSP00000482835.1, ENST00000618940.4
    Conserved Domains (4) summary
    smart00809
    Location:731 → 831
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:840 → 950
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  3. XM_047435509.1 → XP_047291465.1  AP-2 complex subunit beta isoform X2

  4. XM_047435510.1 → XP_047291466.1  AP-2 complex subunit beta isoform X4

    UniProtKB/Swiss-Prot
    A6NJP3, P21851, P63010, Q7Z451, Q96J19

  5. XM_011524449.4 → XP_011522751.1  AP-2 complex subunit beta isoform X1

    See identical proteins and their annotated locations for XP_011522751.1

    UniProtKB/TrEMBL
    A8K0G3
    Conserved Domains (4) summary
    smart00809
    Location:731 → 825
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:872 → 982
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  6. XM_005257937.5 → XP_005257994.1  AP-2 complex subunit beta isoform X3

    See identical proteins and their annotated locations for XP_005257994.1

    UniProtKB/TrEMBL
    A0A140VJE8, A8K0G3
    Conserved Domains (4) summary
    smart00809
    Location:731 → 831
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:840 → 950
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  7. XM_047435508.1 → XP_047291464.1  AP-2 complex subunit beta isoform X2

  8. XM_017024284.3 → XP_016879773.1  AP-2 complex subunit beta isoform X4

    UniProtKB/Swiss-Prot
    A6NJP3, P21851, P63010, Q7Z451, Q96J19
    UniProtKB/TrEMBL
    A8K0G3
    Conserved Domains (4) summary
    smart00809
    Location:717 → 817
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:826 → 936
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  9. XM_011524448.3 → XP_011522750.1  AP-2 complex subunit beta isoform X1

    See identical proteins and their annotated locations for XP_011522750.1

    UniProtKB/TrEMBL
    A8K0G3
    Conserved Domains (4) summary
    smart00809
    Location:731 → 825
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:872 → 982
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  10. XM_011524451.3 → XP_011522753.1  AP-2 complex subunit beta isoform X2

    UniProtKB/TrEMBL
    A8K0G3
    Conserved Domains (4) summary
    smart00809
    Location:717 → 811
    Alpha_adaptinC2; Adaptin C-terminal domain
    smart01020
    Location:858 → 968
    B2-adapt-app_C; Beta2-adaptin appendage, C-terminal sub-domain
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region

  11. XM_047435512.1 → XP_047291468.1  AP-2 complex subunit beta isoform X6

    Related
    ENSP00000478115.1, ENST00000612116.5

  12. XM_017024287.3 → XP_016879776.1  AP-2 complex subunit beta isoform X6

    UniProtKB/TrEMBL
    A0A087WU93
    Related
    ENSP00000479691.1, ENST00000614600.4
    Conserved Domains (3) summary
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region
    pfam12717
    Location:99 → 268
    Cnd1; non-SMC mitotic condensation complex subunit 1
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]

  13. XM_005257941.4 → XP_005257998.1  AP-2 complex subunit beta isoform X6

    UniProtKB/TrEMBL
    A0A087WU93
    Related
    ENSP00000478471.1, ENST00000616784.4
    Conserved Domains (3) summary
    pfam01602
    Location:11 → 534
    Adaptin_N; Adaptin N terminal region
    pfam12717
    Location:99 → 268
    Cnd1; non-SMC mitotic condensation complex subunit 1
    sd00044
    Location:51 → 75
    HEAT; HEAT repeat [structural motif]

  14. XM_047435511.1 → XP_047291467.1  AP-2 complex subunit beta isoform X5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    36535193..36674326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054315296.1 → XP_054171271.1  AP-2 complex subunit beta isoform X6

  2. XM_054315295.1 → XP_054171270.1  AP-2 complex subunit beta isoform X6

  3. XM_054315284.1 → XP_054171259.1  AP-2 complex subunit beta isoform X1

  4. XM_054315287.1 → XP_054171262.1  AP-2 complex subunit beta isoform X2

  5. XM_054315290.1 → XP_054171265.1  AP-2 complex subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A140VJE8

  6. XM_054315292.1 → XP_054171267.1  AP-2 complex subunit beta isoform X4

    UniProtKB/Swiss-Prot
    A6NJP3, P21851, P63010, Q7Z451, Q96J19

  7. XM_054315289.1 → XP_054171264.1  AP-2 complex subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A140VJE8

  8. XM_054315291.1 → XP_054171266.1  AP-2 complex subunit beta isoform X4

    UniProtKB/Swiss-Prot
    A6NJP3, P21851, P63010, Q7Z451, Q96J19

  9. XM_054315283.1 → XP_054171258.1  AP-2 complex subunit beta isoform X1

  10. XM_054315286.1 → XP_054171261.1  AP-2 complex subunit beta isoform X2

  11. XM_054315294.1 → XP_054171269.1  AP-2 complex subunit beta isoform X6

  12. XM_054315285.1 → XP_054171260.1  AP-2 complex subunit beta isoform X1

  13. XM_054315288.1 → XP_054171263.1  AP-2 complex subunit beta isoform X2

  14. XM_054315293.1 → XP_054171268.1  AP-2 complex subunit beta isoform X5

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P63010.1 GenPept UniProtKB/Swiss-Prot:P63010

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