H2-Ea-ps histocompatibility 2, class II antigen E alpha, pseudogene [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: H2-Ea-psprovided by MGI
Official Full Name: histocompatibility 2, class II antigen E alpha, pseudogeneprovided by MGI
Primary source: MGI:MGI:95900
Gene type: protein coding
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ia3; Ia-3; H-2Ea; H2-Ea; I-Ealpha; E-alpha-f
Summary: This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5' end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. [provided by RefSeq, Aug 2010]
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Names: histocompatibility 2, class II antigen E alpha, pseudogene; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H2-IE-alpha; I-E alpha MHC class II; MHC class II antigen E alpha; MHC class II protein

Nucleotide		Protein	Strain
Heading	Accession and Version	Protein	Strain