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Gpr83 G protein-coupled receptor 83 [ Rattus norvegicus (Norway rat) ]

Gene ID: 140595, updated on 4-Jan-2025

Summary

Official Symbol
Gpr83provided by RGD
Official Full Name
G protein-coupled receptor 83provided by RGD
Primary source
RGD:619891
See related
EnsemblRapid:ENSRNOG00000030318 AllianceGenome:RGD:619891
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gir
Summary
Predicted to enable neuropeptide receptor activity. Predicted to be involved in feeding behavior; neuropeptide signaling pathway; and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within response to glucocorticoid. Predicted to be located in non-motile cilium. Predicted to be active in plasma membrane. Orthologous to human GPR83 (G protein-coupled receptor 83). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Adrenal (RPKM 51.5), Brain (RPKM 23.9) and 1 other tissue See more
Orthologs
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Genomic context

See Gpr83 in Genome Data Viewer
Location:
8q12
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (19974995..19985483)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (11693540..11704028)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (13365583..13376071)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 11 open reading frame 97 Neighboring gene MRE11 homolog, double strand break repair nuclease Neighboring gene ankyrin repeat domain 49 Neighboring gene uncharacterized LOC102549408 Neighboring gene dipeptidylpeptidase 3, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity  
enables G protein-coupled receptor activity  
enables neuropeptide Y receptor activity  
enables neuropeptide receptor activity  
enables neuropeptide receptor activity  
Component Evidence Code Pubs
located_in cilium  
located_in non-motile cilium  
located_in non-motile cilium  
is_active_in plasma membrane  
located_in plasma membrane  
located_in plasma membrane  

General protein information

Preferred Names
G-protein coupled receptor 83
Names
glucocorticoid-induced receptor
probable G-protein coupled receptor 83

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080411.2NP_536336.1  G-protein coupled receptor 83 precursor

    See identical proteins and their annotated locations for NP_536336.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    Q8VHD7
    UniProtKB/TrEMBL
    A0A8I5ZSC1
    Related
    ENSRNOP00000043707.1, ENSRNOT00000044945.4
    Conserved Domains (2) summary
    pfam00001
    Location:87344
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:77224
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    19974995..19985483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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