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mt-atp6 ATP synthase 6, mitochondrial [ Danio rerio (zebrafish) ]

Gene ID: 140519, updated on 27-Mar-2024

Summary

Official Symbol
mt-atp6provided by ZNC
Official Full Name
ATP synthase 6, mitochondrialprovided by ZNC
Primary source
ZFIN:ZDB-GENE-011205-18
See related
AllianceGenome:ZFIN:ZDB-GENE-011205-18
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
mtatp6; ATP6
Summary
Predicted to enable proton transmembrane transporter activity. Predicted to be involved in ATP synthesis coupled proton transport. Predicted to act upstream of or within ATP biosynthetic process and ion transport. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. Is expressed in female organism. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; NARP syndrome; Parkinson's disease; multiple sclerosis; and systemic lupus erythematosus. Orthologous to human MT-ATP6 (mitochondrially encoded ATP synthase membrane subunit 6). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) MT (non-nuclear) NC_002333.2 (9052..9735)
105 previous assembly GRCz10 (GCF_000002035.5) MT (non-nuclear) NC_002333.2 (9052..9735)

Chromosome MT - NC_002333.2Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit II Neighboring gene tRNA-Lys Neighboring gene ATP synthase 8 Neighboring gene cytochrome c oxidase subunit III Neighboring gene tRNA-Gly Neighboring gene NADH dehydrogenase subunit 3 Neighboring gene tRNA-Arg

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

  • zgc:85637

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within ATP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in proton motive force-driven ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
part_of mitochondrial proton-transporting ATP synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ATP synthase 6
Names
ATP synthase F0 subunit 6

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002333.2 Reference assembly

    Range
    9052..9735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_059336.1 ATP synthase F0 subunit 6 (mitochondrion) [Danio rerio]

    See identical proteins and their annotated locations for NP_059336.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9MIY5
    UniProtKB/TrEMBL
    A0A0A0VDB1
    Related
    ENSDARP00000087874.3
    Conserved Domains (1) summary
    MTH00132
    Location:1227
    ATP6; ATP synthase F0 subunit 6; Provisional