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Epb41l1 erythrocyte membrane protein band 4.1 like 1 [ Mus musculus (house mouse) ]

Gene ID: 13821, updated on 21-Apr-2024

Summary

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Official Symbol
Epb41l1provided by MGI
Official Full Name
erythrocyte membrane protein band 4.1 like 1provided by MGI
Primary source
MGI:MGI:103010
See related
Ensembl:ENSMUSG00000027624 AllianceGenome:MGI:103010
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4.1N; NBL1; Epb4.1l1; mKIAA0338
Summary
Predicted to enable signaling receptor binding activity. Predicted to be involved in actomyosin structure organization. Located in postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and respiratory system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 11. Orthologous to human EPB41L1 (erythrocyte membrane protein band 4.1 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cortex adult (RPKM 33.4), cerebellum adult (RPKM 32.7) and 20 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 H1; 2 77.39 cM
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (156255918..156385134)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (156417595..156543214)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 14170 Neighboring gene non-coding RNA activated by DNA damage Neighboring gene ribosomal protein L37a pseudogene Neighboring gene STARR-seq mESC enhancer starr_06170 Neighboring gene STARR-seq mESC enhancer starr_06171 Neighboring gene predicted gene, 33977 Neighboring gene STARR-seq mESC enhancer starr_06172 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:156373177-156373360 Neighboring gene AAR2 splicing factor homolog Neighboring gene predicted gene 14169

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems. Wang H, et al. Sci Rep, 2020 Oct 12. PMID 33046791, Free PMC Article
  2. Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance. Wang D, et al. Protein Cell, 2021 Feb. PMID 32448967, Free PMC Article
  3. 4.1N binding regions of inositol 1,4,5-trisphosphate receptor type 1. Fukatsu K, et al. Biochem Biophys Res Commun, 2006 Apr 7. PMID 16487933
  4. The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression. Wozny C, et al. J Cell Sci, 2009 Mar 1. PMID 19225127
  5. A novel neuron-enriched homolog of the erythrocyte membrane cytoskeletal protein 4.1. Walensky LD, et al. J Neurosci, 1999 Aug 1. PMID 10414974, Free PMC Article

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance.
    Title: Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance.
  2. Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems.
    Title: Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems.
  3. study describes a previously unknown mechanism that governs activity-dependent GluR1 trafficking, reveals an interaction between AMPAR palmitoylation and phosphorylation, and underscores the importance of 4.1N in AMPAR trafficking and synaptic plasticity.
    Title: Regulation of AMPA receptor extrasynaptic insertion by 4.1N, phosphorylation and palmitoylation.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (4)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables cytoskeletal protein binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
  
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in actomyosin structure organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  
located_in synaptic membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
band 4.1-like protein 1
Names
erythrocyte protein band 4.1 like 1
neuronal protein 4.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006664.3 → NP_001006665.1  band 4.1-like protein 1 isoform a

    See identical proteins and their annotated locations for NP_001006665.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 3 and 4 all encode isoform a.
    Source sequence(s)
    AL929153, BF464311, CJ113617
    Consensus CDS
    CCDS16966.1
    UniProtKB/TrEMBL
    A2AUK5, B6ZHC9
    Related
    ENSMUSP00000029155.9, ENSMUST00000029155.16
    Conserved Domains (7) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam00373
    Location:183 → 288
    FERM_M; FERM central domain
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:741 → 866
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 425
    FA; FERM adjacent (FA)
    pfam09379
    Location:101 → 164
    FERM_N; FERM N-terminal domain

  2. NM_001291120.1 → NP_001278049.1  band 4.1-like protein 1 isoform a

    See identical proteins and their annotated locations for NP_001278049.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 3 and 4 all encode isoform a.
    Source sequence(s)
    AK147611, AL929153, BF464311
    Consensus CDS
    CCDS16966.1
    UniProtKB/TrEMBL
    A2AUK5, B6ZHC9
    Related
    ENSMUSP00000099426.4, ENSMUST00000103137.10
    Conserved Domains (7) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam00373
    Location:183 → 288
    FERM_M; FERM central domain
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:741 → 866
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 425
    FA; FERM adjacent (FA)
    pfam09379
    Location:101 → 164
    FERM_N; FERM N-terminal domain

  3. NM_001291121.1 → NP_001278050.1  band 4.1-like protein 1 isoform c

    See identical proteins and their annotated locations for NP_001278050.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a.
    Source sequence(s)
    AK147611, AL929153, BF464311
    Consensus CDS
    CCDS71169.1
    UniProtKB/TrEMBL
    A2AUK8, B6ZHC9
    Related
    ENSMUSP00000105205.3, ENSMUST00000109577.9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:482 → 512
    SAB; SAB domain
    pfam05902
    Location:730 → 854
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  4. NM_001291122.1 → NP_001278051.1  band 4.1-like protein 1 isoform d

    See identical proteins and their annotated locations for NP_001278051.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and lacks two alternate in-frame exons in the central coding region, compared to variant 1. The encoded isoform (d) is shorter than isoform a.
    Source sequence(s)
    AK147611, AL929153, BF464311
    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:482 → 512
    SAB; SAB domain
    pfam05902
    Location:594 → 718
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  5. NM_001291123.1 → NP_001278052.1  band 4.1-like protein 1 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, and uses an alternate in-frame splice site and lacks two in-frame exons in the central coding region, compared to variant 1. The encoded isoform (e) is shorter than isoform a.
    Source sequence(s)
    AK147272, AK147611, AL929153, BF464311
    Consensus CDS
    CCDS71170.1
    UniProtKB/TrEMBL
    A2AUK7, B6ZHC9
    Related
    ENSMUSP00000105202.2, ENSMUST00000109574.8
    Conserved Domains (7) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam00373
    Location:183 → 288
    FERM_M; FERM central domain
    pfam04382
    Location:481 → 511
    SAB; SAB domain
    pfam05902
    Location:592 → 717
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 425
    FA; FERM adjacent (FA)
    pfam09379
    Location:101 → 164
    FERM_N; FERM N-terminal domain

  6. NM_001368800.1 → NP_001355729.1  band 4.1-like protein 1 isoform f

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) encodes the longest isoform (f).
    Source sequence(s)
    AL928935, AL929153
    Consensus CDS
    CCDS89573.1
    UniProtKB/TrEMBL
    E9PV14
    Related
    ENSMUSP00000121161.4, ENSMUST00000125153.10
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:492 → 523
    SAB; SAB domain
    pfam05902
    Location:1419 → 1543
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  7. NM_001368801.1 → NP_001355730.1  band 4.1-like protein 1 isoform g

    Status: VALIDATED

    Source sequence(s)
    AL928935, AL929153
    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:486 → 516
    SAB; SAB domain
    pfam05902
    Location:734 → 858
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  8. NM_001368802.1 → NP_001355731.1  band 4.1-like protein 1 isoform h

    Status: VALIDATED

    Source sequence(s)
    AL929153
    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (6) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    PRK08691
    Location:396 → 598
    PRK08691; DNA polymerase III subunits gamma and tau; Validated
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 523
    SAB; SAB domain
    pfam05902
    Location:741 → 865
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  9. NM_001368803.1 → NP_001355732.1  band 4.1-like protein 1 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variant 12, encodes isoform i.
    Source sequence(s)
    AL928935, AL929153
    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (6) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    PRK08691
    Location:396 → 599
    PRK08691; DNA polymerase III subunits gamma and tau; Validated
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:494 → 524
    SAB; SAB domain
    pfam05902
    Location:756 → 809
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  10. NM_001368804.1 → NP_001355733.1  band 4.1-like protein 1 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), as well as variant 11, encodes isoform i.
    Source sequence(s)
    AL929153
    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (6) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    PRK08691
    Location:396 → 599
    PRK08691; DNA polymerase III subunits gamma and tau; Validated
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:494 → 524
    SAB; SAB domain
    pfam05902
    Location:756 → 809
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  11. NM_013510.4 → NP_038538.1  band 4.1-like protein 1 isoform a

    See identical proteins and their annotated locations for NP_038538.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform (a). Variants 1, 3 and 4 all encode isoform a.
    Source sequence(s)
    AK147611, AL929153, BF464311
    Consensus CDS
    CCDS16966.1
    UniProtKB/TrEMBL
    A2AUK5, B6ZHC9
    Related
    ENSMUSP00000099425.2, ENSMUST00000103136.8
    Conserved Domains (7) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam00373
    Location:183 → 288
    FERM_M; FERM central domain
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:741 → 866
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 425
    FA; FERM adjacent (FA)
    pfam09379
    Location:101 → 164
    FERM_N; FERM N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    156255918..156385134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498711.5 → XP_006498774.1  band 4.1-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_006498774.1

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:1453 → 1577
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

  2. XM_030247282.2 → XP_030103142.1  band 4.1-like protein 1 isoform X14

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (6) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    PRK08691
    Location:396 → 599
    PRK08691; DNA polymerase III subunits gamma and tau; Validated
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:494 → 524
    SAB; SAB domain
    pfam05902
    Location:756 → 809
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  3. XM_011239275.4 → XP_011237577.1  band 4.1-like protein 1 isoform X5

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 523
    SAB; SAB domain
    pfam05902
    Location:1452 → 1576
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  4. XM_030247271.2 → XP_030103131.1  band 4.1-like protein 1 isoform X10

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (6) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    PRK08691
    Location:396 → 598
    PRK08691; DNA polymerase III subunits gamma and tau; Validated
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 523
    SAB; SAB domain
    pfam05902
    Location:741 → 865
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  5. XM_030247268.2 → XP_030103128.1  band 4.1-like protein 1 isoform X7

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:486 → 516
    SAB; SAB domain
    pfam05902
    Location:1445 → 1569
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  6. XM_030247284.2 → XP_030103144.1  band 4.1-like protein 1 isoform X15

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:486 → 516
    SAB; SAB domain
    pfam05902
    Location:748 → 801
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  7. XM_030247286.2 → XP_030103146.1  band 4.1-like protein 1 isoform X17

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:486 → 516
    SAB; SAB domain
    pfam05902
    Location:598 → 722
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  8. XM_006498714.4 → XP_006498777.1  band 4.1-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_006498777.1

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:1453 → 1577
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

  9. XM_030247275.2 → XP_030103135.1  band 4.1-like protein 1 isoform X10

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (6) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    PRK08691
    Location:396 → 598
    PRK08691; DNA polymerase III subunits gamma and tau; Validated
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 523
    SAB; SAB domain
    pfam05902
    Location:741 → 865
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  10. XM_006498713.4 → XP_006498776.1  band 4.1-like protein 1 isoform X4

    See identical proteins and their annotated locations for XP_006498776.1

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:1453 → 1577
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

  11. XM_036158182.1 → XP_036014075.1  band 4.1-like protein 1 isoform X4

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:1453 → 1577
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

  12. XM_036158177.1 → XP_036014070.1  band 4.1-like protein 1 isoform X4

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:1453 → 1577
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

  13. XM_030247281.2 → XP_030103141.1  band 4.1-like protein 1 isoform X13

    UniProtKB/TrEMBL
    A2AUK8, B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:482 → 512
    SAB; SAB domain
    pfam05902
    Location:730 → 854
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  14. XM_030247288.2 → XP_030103148.1  band 4.1-like protein 1 isoform X18

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:482 → 512
    SAB; SAB domain
    pfam05902
    Location:594 → 718
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  15. XM_011239276.3 → XP_011237578.1  band 4.1-like protein 1 isoform X7

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:486 → 516
    SAB; SAB domain
    pfam05902
    Location:1445 → 1569
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  16. XM_030247277.2 → XP_030103137.1  band 4.1-like protein 1 isoform X12

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:486 → 516
    SAB; SAB domain
    pfam05902
    Location:734 → 858
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  17. XM_030247290.2 → XP_030103150.1  band 4.1-like protein 1 isoform X19

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:474 → 504
    SAB; SAB domain
    pfam05902
    Location:586 → 710
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  18. XM_006498708.4 → XP_006498771.1  band 4.1-like protein 1 isoform X1

    Conserved Domains (5) summary
    smart00295
    Location:111 → 300
    B41; Band 4.1 homologues
    cd13184
    Location:295 → 388
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:506 → 536
    SAB; SAB domain
    pfam05902
    Location:1465 → 1589
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:397 → 438
    FA; FERM adjacent (FA)

  19. XM_011239279.1 → XP_011237581.1  band 4.1-like protein 1 isoform X8

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:494 → 524
    SAB; SAB domain
    pfam05902
    Location:1467 → 1520
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  20. XM_011239281.1 → XP_011237583.1  band 4.1-like protein 1 isoform X16

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:494 → 524
    SAB; SAB domain
    pfam05902
    Location:606 → 730
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  21. XM_036158201.1 → XP_036014094.1  band 4.1-like protein 1 isoform X20

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:493 → 524
    SAB; SAB domain
    pfam05902
    Location:620 → 673
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

  22. XM_011239277.1 → XP_011237579.1  band 4.1-like protein 1 isoform X2

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:482 → 512
    SAB; SAB domain
    pfam05902
    Location:1441 → 1565
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  23. XM_030247261.1 → XP_030103121.1  band 4.1-like protein 1 isoform X3

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:481 → 511
    SAB; SAB domain
    pfam05902
    Location:1440 → 1564
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  24. XM_036158191.1 → XP_036014084.1  band 4.1-like protein 1 isoform X9

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:481 → 511
    SAB; SAB domain
    pfam05902
    Location:729 → 853
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

  25. XM_011239278.1 → XP_011237580.1  band 4.1-like protein 1 isoform X6

    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:474 → 504
    SAB; SAB domain
    pfam05902
    Location:1433 → 1557
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 426
    FA; FERM adjacent (FA)

  26. XM_036158196.1 → XP_036014089.1  band 4.1-like protein 1 isoform X11

    UniProtKB/TrEMBL
    B6ZHC9
    Conserved Domains (5) summary
    smart00295
    Location:99 → 288
    B41; Band 4.1 homologues
    cd13184
    Location:283 → 376
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:474 → 504
    SAB; SAB domain
    pfam05902
    Location:722 → 846
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:385 → 428
    FA; FERM adjacent (FA)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001003815.2: Suppressed sequence

    Description
    NM_001003815.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Z2H5.2 GenPept UniProtKB/Swiss-Prot:Q9Z2H5

Gene LinkOut

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