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LOC1276976 2-oxoglutarate dehydrogenase complex component E1 [ Anopheles gambiae (African malaria mosquito) ]

Gene ID: 1276976, updated on 31-Jan-2024

Summary

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Gene symbol
LOC1276976
Gene description
2-oxoglutarate dehydrogenase complex component E1
Gene type
protein coding
RefSeq status
MODEL
Organism
Anopheles gambiae
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
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Genomic context

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Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (99379589..99403443, complement)

Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene vitamin K-dependent gamma-carboxylase Neighboring gene SET domain-containing protein 4 Neighboring gene iron-sulfur clusters transporter ABCB7, mitochondrial Neighboring gene RNA-binding protein 8A Neighboring gene E3 ubiquitin-protein ligase TRAIP Neighboring gene general odorant-binding protein 70

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Anopheles gambiae genome: an update. Mongin E, et al. Trends Parasitol, 2004 Feb. PMID 14747013
  2. The genome sequence of the malaria mosquito Anopheles gambiae. Holt RA, et al. Science, 2002 Oct 4. PMID 12364791

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of oxoglutarate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
2-oxoglutarate dehydrogenase complex component E1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference idAnoGambNW_F1_1 Primary Assembly

Genomic

  1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

    Range
    99379589..99403443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_061648813.1 → XP_061504797.1  2-oxoglutarate dehydrogenase complex component E1 isoform X4

  2. XM_061648811.1 → XP_061504795.1  2-oxoglutarate dehydrogenase complex component E1 isoform X3

  3. XM_061648804.1 → XP_061504788.1  2-oxoglutarate dehydrogenase complex component E1 isoform X1

  4. XM_061648809.1 → XP_061504793.1  2-oxoglutarate dehydrogenase complex component E1 isoform X2

  5. XM_061648819.1 → XP_061504803.1  2-oxoglutarate dehydrogenase complex component E1 isoform X7

    UniProtKB/TrEMBL
    A7UU86

  6. XM_061648816.1 → XP_061504800.1  2-oxoglutarate dehydrogenase complex component E1 isoform X6

  7. XM_061648824.1 → XP_061504808.1  2-oxoglutarate dehydrogenase complex component E1 isoform X10

    UniProtKB/TrEMBL
    A7UU84

  8. XM_061648820.1 → XP_061504804.1  2-oxoglutarate dehydrogenase complex component E1 isoform X8

    UniProtKB/TrEMBL
    A7UU87

  9. XM_061648822.1 → XP_061504806.1  2-oxoglutarate dehydrogenase complex component E1 isoform X9

    UniProtKB/TrEMBL
    Q7PIB4

  10. XM_001688806.2 → XP_001688858.1  2-oxoglutarate dehydrogenase complex component E1 isoform X8

    See identical proteins and their annotated locations for XP_001688858.1

    UniProtKB/TrEMBL
    A7UU87
    Conserved Domains (1) summary
    PRK09404
    Location:52 → 1033
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  11. XM_061648814.1 → XP_061504798.1  2-oxoglutarate dehydrogenase complex component E1 isoform X5

  12. XM_061648805.1 → XP_061504789.1  2-oxoglutarate dehydrogenase complex component E1 isoform X1

  13. XM_001688807.2 → XP_001688859.1  2-oxoglutarate dehydrogenase complex component E1 isoform X10

    See identical proteins and their annotated locations for XP_001688859.1

    UniProtKB/TrEMBL
    A7UU84
    Conserved Domains (1) summary
    PRK09404
    Location:52 → 1013
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  14. XM_061648818.1 → XP_061504802.1  2-oxoglutarate dehydrogenase complex component E1 isoform X7

    UniProtKB/TrEMBL
    A7UU86

  15. XM_061648808.1 → XP_061504792.1  2-oxoglutarate dehydrogenase complex component E1 isoform X3

  16. XM_316396.5 → XP_316396.4  2-oxoglutarate dehydrogenase complex component E1 isoform X9

    See identical proteins and their annotated locations for XP_316396.4

    UniProtKB/TrEMBL
    Q7PIB4
    Conserved Domains (5) summary
    PRK09404
    Location:52 → 1018
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:271 → 533
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:654 → 868
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:50 → 85
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:875 → 1017
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  17. XM_061648815.1 → XP_061504799.1  2-oxoglutarate dehydrogenase complex component E1 isoform X6

  18. XM_061648807.1 → XP_061504791.1  2-oxoglutarate dehydrogenase complex component E1 isoform X2

  19. XM_061648825.1 → XP_061504809.1  2-oxoglutarate dehydrogenase complex component E1 isoform X10

    UniProtKB/TrEMBL
    A7UU84

  20. XM_061648812.1 → XP_061504796.1  2-oxoglutarate dehydrogenase complex component E1 isoform X3

  21. XM_061648821.1 → XP_061504805.1  2-oxoglutarate dehydrogenase complex component E1 isoform X8

    UniProtKB/TrEMBL
    A7UU87

  22. XM_061648806.1 → XP_061504790.1  2-oxoglutarate dehydrogenase complex component E1 isoform X1

  23. XM_061648823.1 → XP_061504807.1  2-oxoglutarate dehydrogenase complex component E1 isoform X9

    UniProtKB/TrEMBL
    Q7PIB4

  24. XM_061648810.1 → XP_061504794.1  2-oxoglutarate dehydrogenase complex component E1 isoform X2

Nucleotide Protein Strain
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