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Taf9 TATA-box binding protein associated factor 9 [ Mus musculus (house mouse) ]

Gene ID: 108143, updated on 5-Mar-2024

Summary

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Official Symbol
Taf9provided by MGI
Official Full Name
TATA-box binding protein associated factor 9provided by MGI
Primary source
MGI:MGI:1888697
See related
Ensembl:ENSMUSG00000052293 Ensembl:ENSMUSG00000078941 AllianceGenome:MGI:1888697
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Taf2g; TAFII31; TAFII32; 2310012M09Rik
Summary
Enables DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in brain; genitourinary system; limb; tail; and thymus primordium. Orthologous to human TAF9 (TATA-box binding protein associated factor 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 265.3), CNS E14 (RPKM 68.0) and 18 other tissues See more
Orthologs
human all
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Genomic context

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Location:
13 D1; 13 53.23 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (100787851..100792568)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (100651343..100656060)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene MARVEL (membrane-associating) domain containing 2 Neighboring gene predicted gene, 24261 Neighboring gene RAD17 checkpoint clamp loader component Neighboring gene STARR-positive B cell enhancer ABC_E7268 Neighboring gene adenylate kinase 6 Neighboring gene STARR-seq mESC enhancer starr_35476 Neighboring gene coiled-coil domain containing 125 Neighboring gene cyclin dependent kinase 7 Neighboring gene STARR-seq mESC enhancer starr_35477 Neighboring gene STARR-positive B cell enhancer ABC_E7269 Neighboring gene STARR-positive B cell enhancer mm9_chr13:101513935-101514236 Neighboring gene mitochondrial ribosomal protein S36

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Distinct modes of gene regulation by a cell-specific transcriptional activator. Sengupta T, et al. Proc Natl Acad Sci U S A, 2009 Mar 17. PMID 19251649, Free PMC Article
  2. Neural activity- and development-dependent expression and distribution of CASK interacting nucleosome assembly protein in mouse brain. Lin CW, et al. J Comp Neurol, 2006 Feb 1. PMID 16374801
  3. Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation. Nagy Z, et al. Oncogene, 2007 Aug 13. PMID 17694077
  4. Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates. Schiltz RL, et al. J Biol Chem, 1999 Jan 15. PMID 9880483
  5. Histone-like TAFs within the PCAF histone acetylase complex. Ogryzko VV, et al. Cell, 1998 Jul 10. PMID 9674425

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC117979

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATPase binding ISO
Inferred from Sequence Orthology
more info
  
enables C2H2 zinc finger domain binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
  
contributes_to RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to histone acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables p53 binding ISO
Inferred from Sequence Orthology
more info
  
enables transcription cis-regulatory region binding ISO
Inferred from Sequence Orthology
more info
  
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in RNA polymerase II preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in RNA polymerase II preinitiation complex assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in box C/D snoRNP assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in mRNA transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of DNA-templated transcription NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of response to cytokine stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription initiation by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of DNA repair NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of DNA-templated transcription NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of RNA splicing NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in response to interleukin-1 ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of MLL1 complex ISO
Inferred from Sequence Orthology
more info
  
part_of SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAGA complex ISO
Inferred from Sequence Orthology
more info
  
part_of SAGA complex NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
part_of pre-snoRNP complex ISO
Inferred from Sequence Orthology
more info
  
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIID complex ISO
Inferred from Sequence Orthology
more info
  
part_of transcription factor TFTC complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFTC complex ISO
Inferred from Sequence Orthology
more info
  
part_of transcription factor TFTC complex NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
transcription initiation factor TFIID subunit 9
Names
RNA polymerase II TBP-associated factor subunit G
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32 kDa
transcription initiation factor TFIID 31 kDa subunit
transcription initiation factor TFIID 32 kDa subunit
NP_001015889.1
NP_081415.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015889.2 → NP_001015889.1  transcription initiation factor TFIID subunit 9

    See identical proteins and their annotated locations for NP_001015889.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longer transcript. Variants 1 and 3 encode the same protein.
    Source sequence(s)
    BC096683, BQ839921, BY108476
    Consensus CDS
    CCDS26735.1
    UniProtKB/Swiss-Prot
    Q32P09, Q80XS3, Q8VI33, Q9CV61
    Related
    ENSMUSP00000132143.2, ENSMUST00000167256.8
    Conserved Domains (1) summary
    pfam02291
    Location:9 → 130
    TFIID-31kDa; Transcription initiation factor IID, 31kD subunit

  2. NM_027139.5 → NP_081415.1  transcription initiation factor TFIID subunit 9

    See identical proteins and their annotated locations for NP_081415.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1 and 3 encode the same protein.
    Source sequence(s)
    BC096683, BY108476
    Consensus CDS
    CCDS26735.1
    UniProtKB/Swiss-Prot
    Q32P09, Q80XS3, Q8VI33, Q9CV61
    Related
    ENSMUSP00000081772.7, ENSMUST00000084721.8
    Conserved Domains (1) summary
    pfam02291
    Location:9 → 130
    TFIID-31kDa; Transcription initiation factor IID, 31kD subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    100787851..100792568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VI33.1 GenPept UniProtKB/Swiss-Prot:Q8VI33

Gene LinkOut

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