Camk2d calcium/calmodulin-dependent protein kinase II, delta [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Camk2dprovided by MGI
Official Full Name: calcium/calmodulin-dependent protein kinase II, deltaprovided by MGI
Primary source: MGI:MGI:1341265
See related: Ensembl:ENSMUSG00000053819 AllianceGenome:MGI:1341265
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: CaMK II; [d]-CaMKII; 2810011D23Rik; 8030469K03Rik
Summary: Enables protein serine/threonine kinase activity and transmembrane transporter binding activity. Involved in regulation of relaxation of cardiac muscle. Acts upstream of or within several processes, including G1/S transition of mitotic cell cycle; cardiac muscle contraction; and protein phosphorylation. Located in several cellular components, including T-tubule; axon initial segment; and intercalated disc. Is expressed in several structures, including central nervous system; heart ventricle; olfactory epithelium; renal vasculature; and retina. Orthologous to human CAMK2D (calcium/calmodulin dependent protein kinase II delta). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in bladder adult (RPKM 17.7), adrenal adult (RPKM 15.0) and 24 other tissues See more
Orthologs: human all
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Genomic context

Location:: 3 G1- G2; 3 55.97 cM

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (126389136..126639975)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (126595487..126846326)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Using CRISPR-Cas9/phosphoproteomics to identify substrates of calcium/calmodulin-dependent kinase 2delta.
Title: Using CRISPR-Cas9/phosphoproteomics to identify substrates of calcium/calmodulin-dependent kinase 2δ.
Researches of calcium-activated chloride channel ANO1 intervening amyotrophic lateral sclerosis progression by activating EGFR and CaMKII signaling.
Title: Researches of calcium-activated chloride channel ANO1 intervening amyotrophic lateral sclerosis progression by activating EGFR and CaMKII signaling.
Oxidative stress-induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain.
Title: Oxidative stress-induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain.
Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance.
Title: Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance.
Hyperglycemia regulates cardiac K(+) channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways.
Title: Hyperglycemia regulates cardiac K(+) channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways.
CaMKII exacerbates heart failure progression by activating class I HDACs.
Title: CaMKII exacerbates heart failure progression by activating class I HDACs.
CaMKII(delta) regulates osteoclastogenesis through ERK, JNK, and p38 MAPKs and CREB signalling pathway.
Title: CaMKII(δ) regulates osteoclastogenesis through ERK, JNK, and p38 MAPKs and CREB signalling pathway.
CaM Kinase II-delta Is Required for Diabetic Hyperglycemia and Retinopathy but Not Nephropathy.
Title: CaM Kinase II-δ Is Required for Diabetic Hyperglycemia and Retinopathy but Not Nephropathy.
Phosphorylation of T107 by CamKIIdelta Regulates the Detoxification Efficiency and Proteomic Integrity of Glyoxalase 1.
Title: Phosphorylation of T107 by CamKIIδ Regulates the Detoxification Efficiency and Proteomic Integrity of Glyoxalase 1.
Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-delta in sepsis-associated liver injury.
Title: Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-δ in sepsis-associated liver injury.

Submit: New GeneRIF Correction See all GeneRIFs (60)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (5) 1 citation
Endonuclease-mediated (4)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH126368 (e-PCR)
- UniSTS:163076

RH94737 (e-PCR)
- UniSTS:119984

12.MMHAP21FLD3.seq (e-PCR)
- UniSTS:123105

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables calmodulin binding	IBA Inferred from Biological aspect of Ancestor more info
enables calmodulin binding	ISO Inferred from Sequence Orthology more info
enables calmodulin-dependent protein kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables calmodulin-dependent protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables calmodulin-dependent protein kinase activity	ISO Inferred from Sequence Orthology more info
enables calmodulin-dependent protein kinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nitric-oxide synthase binding	ISO Inferred from Sequence Orthology more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein kinase activity	ISO Inferred from Sequence Orthology more info
enables protein serine/threonine kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein serine/threonine kinase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables protein serine/threonine kinase activity	ISO Inferred from Sequence Orthology more info
enables sodium channel inhibitor activity	ISO Inferred from Sequence Orthology more info
enables titin binding	ISO Inferred from Sequence Orthology more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables transmembrane transporter binding	IPI Inferred from Physical Interaction more info	PubMed
enables transmembrane transporter binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G1/S transition of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within calcium ion transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within calcium ion transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cardiac muscle cell contraction	ISO Inferred from Sequence Orthology more info
involved_in cardiac muscle cell contraction	ISS Inferred from Sequence or Structural Similarity more info	PubMed
acts_upstream_of_or_within cardiac muscle contraction	IDA Inferred from Direct Assay more info	PubMed
involved_in cell growth involved in cardiac muscle cell development	ISO Inferred from Sequence Orthology more info
involved_in endoplasmic reticulum calcium ion homeostasis	ISO Inferred from Sequence Orthology more info
involved_in intracellular potassium ion homeostasis	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of sodium ion transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of sodium ion transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within peptidyl-serine phosphorylation	IDA Inferred from Direct Assay more info	PubMed
involved_in peptidyl-serine phosphorylation	ISO Inferred from Sequence Orthology more info
involved_in peptidyl-threonine phosphorylation	ISO Inferred from Sequence Orthology more info
involved_in peptidyl-threonine phosphorylation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of DNA biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of ERK1 and ERK2 cascade	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of G2/M transition of mitotic cell cycle	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of Rac protein signal transduction	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cardiac muscle cell apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cardiac muscle hypertrophy	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of smooth muscle cell migration	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of vascular associated smooth muscle cell proliferation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein autophosphorylation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein autophosphorylation	ISO Inferred from Sequence Orthology more info
involved_in protein phosphorylation	ISO Inferred from Sequence Orthology more info
involved_in regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	ISO Inferred from Sequence Orthology more info
involved_in regulation of cardiac muscle cell action potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell communication by electrical coupling	ISO Inferred from Sequence Orthology more info
involved_in regulation of cellular localization	ISO Inferred from Sequence Orthology more info
involved_in regulation of membrane depolarization	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein localization to plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in regulation of relaxation of cardiac muscle	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of relaxation of cardiac muscle	ISO Inferred from Sequence Orthology more info
involved_in regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of sodium ion transport	IDA Inferred from Direct Assay more info	PubMed
involved_in relaxation of cardiac muscle	ISO Inferred from Sequence Orthology more info
involved_in relaxation of cardiac muscle	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in response to hypoxia	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in T-tubule	IDA Inferred from Direct Assay more info	PubMed
located_in axon initial segment	IDA Inferred from Direct Assay more info	PubMed
part_of calcium- and calmodulin-dependent protein kinase complex	ISO Inferred from Sequence Orthology more info
is_active_in cochlear hair cell ribbon synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in intercalated disc	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuromuscular junction	IDA Inferred from Direct Assay more info	PubMed
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in postsynaptic cytosol	IDA Inferred from Direct Assay more info	PubMed
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: calcium/calmodulin-dependent protein kinase type II subunit delta

Names: caM kinase II subunit delta; caMK-II subunit delta

NP_001020609.1

EC 2.7.11.17

NP_001020610.1

EC 2.7.11.17

NP_001280592.1

EC 2.7.11.17

NP_001280593.1

EC 2.7.11.17

NP_001280594.1

EC 2.7.11.17

NP_001280595.1

EC 2.7.11.17

NP_001333564.1

EC 2.7.11.17

NP_001333565.1

EC 2.7.11.17

NP_076302.1

EC 2.7.11.17

XP_006500881.1

EC 2.7.11.17

XP_006500882.1

EC 2.7.11.17

XP_006500883.1

EC 2.7.11.17

XP_006500885.1

EC 2.7.11.17

XP_006500886.1

EC 2.7.11.17

XP_006500887.1

EC 2.7.11.17

XP_006500888.1

EC 2.7.11.17

XP_006500889.1

EC 2.7.11.17

XP_006500892.1

EC 2.7.11.17

XP_006500896.1

EC 2.7.11.17

XP_006500897.1

EC 2.7.11.17

XP_006500898.1

EC 2.7.11.17

XP_006500899.1

EC 2.7.11.17

XP_006500902.1

EC 2.7.11.17

XP_017174904.1

EC 2.7.11.17

XP_017174905.1

EC 2.7.11.17

XP_017174906.1

EC 2.7.11.17

XP_017174907.1

EC 2.7.11.17

XP_017174908.1

EC 2.7.11.17

XP_017174909.1

EC 2.7.11.17

XP_017174911.1

EC 2.7.11.17

XP_030108200.1

EC 2.7.11.17

XP_030108201.1

EC 2.7.11.17

XP_030108202.1

EC 2.7.11.17

XP_030108203.1

EC 2.7.11.17

XP_030108204.1

EC 2.7.11.17

XP_030108205.1

EC 2.7.11.17

XP_030108206.1

EC 2.7.11.17

XP_036018696.1

EC 2.7.11.17

XP_036018697.1

EC 2.7.11.17

XP_036018698.1

EC 2.7.11.17

XP_036018699.1

EC 2.7.11.17

XP_036018700.1

EC 2.7.11.17

XP_036018701.1

EC 2.7.11.17

XP_036018702.1

EC 2.7.11.17

XP_036018703.1

EC 2.7.11.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025438.2 → NP_001020609.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 2

See identical proteins and their annotated locations for NP_001020609.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 3' UTR, and has multiple differences in the coding region, resulting in a frameshift compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter compared to isoform 1.

Source sequence(s)

AC102591, AC110174, BP761508

Consensus CDS

CCDS17823.1

UniProtKB/Swiss-Prot

Q3UF87, Q3UQH9, Q5DTK4, Q6PHZ2, Q8CAC5, Q9CZE2

Related

ENSMUSP00000143504.2, ENSMUST00000199300.5

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:346 → 473

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_001025439.2 → NP_001020610.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 1

See identical proteins and their annotated locations for NP_001020610.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes isoform (1).

Source sequence(s)

AC102591, AC110174, AK039076, BP761508

Consensus CDS

CCDS38624.1

UniProtKB/TrEMBL

E9Q1W0

Related

ENSMUSP00000102007.3, ENSMUST00000106399.8

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:380 → 507

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_001293663.1 → NP_001280592.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 4

See identical proteins and their annotated locations for NP_001280592.1

Status: VALIDATED

Description

Transcript Variant: This variant (4) lacks an alternate exon and contains an alternate exon but maintains the reading frame compared to variant 1. The encoded isoform (4) is the same length as isoform 1, but contains a distinct internal segment.

Source sequence(s)

AC102591, AC110174, BP761508

Consensus CDS

CCDS80015.1

UniProtKB/Swiss-Prot

Q6PHZ2

Related

ENSMUSP00000102010.2, ENSMUST00000106402.8

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:380 → 507

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_001293664.1 → NP_001280593.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 5

See identical proteins and their annotated locations for NP_001280593.1

Status: VALIDATED

Description

Transcript Variant: This variant (5) lacks two alternate exons and contains one alternate exon, but maintains the reading frame compared to variant 1. The encoded isoform (5) is shorter than isoform 1.

Source sequence(s)

AC102591, AC110174, AK148840, BP761508

Consensus CDS

CCDS80016.1

UniProtKB/Swiss-Prot

Q6PHZ2

Related

ENSMUSP00000063359.8, ENSMUST00000066466.13

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:360 → 487

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_001293665.1 → NP_001280594.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 6

Status: VALIDATED

Description

Transcript Variant: This variant (6) has multiple differences compared to variant 1. These differences result in a different 5' UTR, cause translation initiation at an alternate start codon and result in a frameshift compared to variant 1. The encoded isoform (6) has distinct N- and C- termini, and is shorter compared to isoform 1.

Source sequence(s)

AC102591, AC110174, BC057103, BP761508

Conserved Domains (2) summary

pfam08332
Location:214 → 341

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:6 → 171

PKc_like; Protein Kinases, catalytic domain
NM_001293666.1 → NP_001280595.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 7

See identical proteins and their annotated locations for NP_001280595.1

Status: VALIDATED

Description

Transcript Variant: This variant (7) lacks several alternate exons, and contains two alternate exons, resulting in a novel 3' coding region compared to variant 1. The encoded isoform (7) is shorter, and has a distinct C-terminus, compared to isoform 1.

Source sequence(s)

AC102591, AC110174, AK032524, BM899824

Consensus CDS

CCDS80017.1

UniProtKB/TrEMBL

Q8CCM0

Related

ENSMUSP00000133019.2, ENSMUST00000163226.8

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
NM_001346635.1 → NP_001333564.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 8

Status: VALIDATED

Source sequence(s)

AC102591, AC110174

Consensus CDS

CCDS84670.1

UniProtKB/TrEMBL

A0A0G2JGS4

Related

ENSMUSP00000143677.2, ENSMUST00000200171.5

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:380 → 507

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_001346636.1 → NP_001333565.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 9

Status: VALIDATED

Source sequence(s)

AC102591, AC110174

Consensus CDS

CCDS84671.1

UniProtKB/TrEMBL

E9Q1T1

Related

ENSMUSP00000129999.2, ENSMUST00000171289.8

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:380 → 507

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
NM_023813.4 → NP_076302.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform 3

See identical proteins and their annotated locations for NP_076302.1

Status: VALIDATED

Description

Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame compared to variant 1. The encoded isoform (3) is shorter than isoform 1.

Source sequence(s)

AC102591, AC110174, AK012702, BP761508

Consensus CDS

CCDS51065.1

UniProtKB/Swiss-Prot

Q6PHZ2

Related

ENSMUSP00000102008.3, ENSMUST00000106400.9

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:346 → 473

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000069.7 Reference GRCm39 C57BL/6J

Range

126389136..126639975

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030252342.1 → XP_030108202.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X20

Conserved Domains (2) summary

pfam08332
Location:251 → 378

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_030252344.1 → XP_030108204.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X25

Conserved Domains (2) summary

pfam08332
Location:251 → 378

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_030252343.1 → XP_030108203.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X24

Conserved Domains (2) summary

pfam08332
Location:231 → 358

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_030252346.1 → XP_030108206.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X30

Conserved Domains (2) summary

pfam08332
Location:231 → 358

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain
XM_006500823.4 → XP_006500886.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X10

See identical proteins and their annotated locations for XP_006500886.1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:357 → 484

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500829.4 → XP_006500892.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X17

Related

ENSMUSP00000102009.3, ENSMUST00000106401.8

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:357 → 484

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500819.4 → XP_006500882.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3

See identical proteins and their annotated locations for XP_006500882.1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:366 → 493

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500825.4 → XP_006500888.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X14

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:366 → 493

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500820.4 → XP_006500883.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X5

See identical proteins and their annotated locations for XP_006500883.1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:360 → 487

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500824.4 → XP_006500887.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X12

See identical proteins and their annotated locations for XP_006500887.1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:356 → 483

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500818.4 → XP_006500881.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1

See identical proteins and their annotated locations for XP_006500881.1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:379 → 506

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017319419.2 → XP_017174908.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X9

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:379 → 506

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017319416.2 → XP_017174905.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:365 → 492

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500822.4 → XP_006500885.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X7

See identical proteins and their annotated locations for XP_006500885.1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:359 → 486

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_030252340.1 → XP_030108200.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X16

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:359 → 486

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500826.4 → XP_006500889.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X15

See identical proteins and their annotated locations for XP_006500889.1

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:345 → 472

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017319420.2 → XP_017174909.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X11

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:357 → 484

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017319417.2 → XP_017174906.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:360 → 487

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036162803.1 → XP_036018696.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X13

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:346 → 473

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_036162804.1 → XP_036018697.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X18

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:346 → 473

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017319415.2 → XP_017174904.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:379 → 506

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017319418.2 → XP_017174907.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X8

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:359 → 486

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_017319422.2 → XP_017174911.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X36

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:366 → 493

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_030252341.1 → XP_030108201.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X19

Conserved Domains (2) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

pfam08332
Location:345 → 472

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
XM_006500834.5 → XP_006500897.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X23

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_006500833.4 → XP_006500896.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X22

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_006500835.4 → XP_006500898.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X26

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_030252345.1 → XP_030108205.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X28

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_006500839.5 → XP_006500902.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X32

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_036162809.1 → XP_036018702.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X34

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_036162808.1 → XP_036018701.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X33

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_036162807.1 → XP_036018700.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X31

Conserved Domains (1) summary

cd14086
Location:12 → 303

STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
XM_036162805.1 → XP_036018698.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X21

Conserved Domains (2) summary

pfam08332
Location:248 → 375

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:6 → 171

PKc_like; Protein Kinases, catalytic domain
XM_036162806.1 → XP_036018699.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X29

Conserved Domains (2) summary

pfam08332
Location:214 → 341

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:6 → 171

PKc_like; Protein Kinases, catalytic domain
XM_036162810.1 → XP_036018703.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X35

Conserved Domains (2) summary

pfam08332
Location:214 → 341

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:6 → 171

PKc_like; Protein Kinases, catalytic domain
XM_006500836.4 → XP_006500899.1 calcium/calmodulin-dependent protein kinase type II subunit delta isoform X27

Conserved Domains (2) summary

pfam08332
Location:217 → 344

CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

cl21453
Location:1 → 174

PKc_like; Protein Kinases, catalytic domain