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Rnu12 RNA U12, small nuclear [ Mus musculus (house mouse) ]

Gene ID: 104307, updated on 8-Feb-2024

Summary

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Official Symbol
Rnu12provided by MGI
Official Full Name
RNA U12, small nuclearprovided by MGI
Primary source
MGI:MGI:1336893
See related
Ensembl:ENSMUSG00000065176 AllianceGenome:MGI:1336893
Gene type
snRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Is expressed in several structures, including branchial arch; limb; limb primordium; neural retina; and somite. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Rnu12 in Genome Data Viewer
Location:
15 E1; 15 39.4 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (83033846..83033995)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (83149645..83149794)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene serine hydrolase-like Neighboring gene ribosomal RNA processing 7 homolog A Neighboring gene polymerase (DNA-directed), delta interacting protein 3 Neighboring gene cytochrome b5 reductase 3 Neighboring gene STARR-positive B cell enhancer ABC_E4142 Neighboring gene STARR-seq mESC enhancer starr_39316 Neighboring gene STARR-seq mESC enhancer starr_39317 Neighboring gene STARR-seq mESC enhancer starr_39321 Neighboring gene alpha 1,4-galactosyltransferase Neighboring gene STARR-positive B cell enhancer ABC_E5503

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Minor splicing snRNAs are enriched in the developing mouse CNS and are crucial for survival of differentiating retinal neurons. Baumgartner M, et al. Dev Neurobiol, 2015 Sep. PMID 25492806
  2. U12 snRNA in vertebrates: evolutionary conservation of 5' sequences implicated in splicing of pre-mRNAs containing a minor class of introns. Tarn WY, et al. RNA, 1995 Aug. PMID 7489523, Free PMC Article
  3. The divergent U12-type spliceosome is required for pre-mRNA splicing and is essential for development in Drosophila. Otake LR, et al. Mol Cell, 2002 Feb. PMID 11864616
  4. Minor spliceosome components are predominantly localized in the nucleus. Pessa HK, et al. Proc Natl Acad Sci U S A, 2008 Jun 24. PMID 18559850, Free PMC Article
  5. Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Bizen N, et al. Cell Death Differ, 2022 May. PMID 34974536, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_004432.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL591952
    Related
    ENSMUST00000083242.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    83033846..83033995
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases