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LOC102723407 immunoglobulin heavy variable 4-38-2-like [ Homo sapiens (human) ]

Gene ID: 102723407, updated on 10-Mar-2024

Summary

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Gene symbol
LOC102723407
Gene description
immunoglobulin heavy variable 4-38-2-like
Gene type
protein coding
RefSeq status
MODEL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IGH; IgA; IgT; IGH@; IGVH; ighv; IGHV4; IGVH4b; IGHV4-b; IGVH4-b; IGHV4-30; IGHV4-39; IGVH4-39; IGHV4-38-2
Orthologs
all
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Genomic context

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See LOC102723407 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 Unlocalized Scaffold NT_187381.1 (41382..43488)

NT_187381.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905324 Neighboring gene uncharacterized LOC105379527 Neighboring gene immunoglobulin heavy variable 3-9

Genomic regions, transcripts, and products

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Genomic Sequence:
NT_187381 Chromosome 14 Unlocalized Scaffold Reference GRCh38.p14 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen. Ahmed R, et al. Cell, 2019 May 30. PMID 31150624, Free PMC Article
  2. Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Goodwin E, et al. Immunity, 2018 Feb 20. PMID 29396163, Free PMC Article
  3. Chronic lymphocytic leukemia cells diversify and differentiate in vivo via a nonclassical Th1-dependent, Bcl-6-deficient process. Patten PE, et al. JCI Insight, 2016 Apr 7. PMID 27158669, Free PMC Article
  4. Torque teno virus 10 isolated by genome amplification techniques from a patient with concomitant chronic lymphocytic leukemia and polycythemia vera. Chu CC, et al. Mol Med, 2011. PMID 21953418, Free PMC Article
  5. Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation. Catera R, et al. Mol Med, 2008 Nov-Dec. PMID 19009014, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TLR4, IgA and EpCAM Expression in Colorectal Cancer and Their Possible Association with Microbiota as a Pathogenic Factor; An Immunohistochemical and Genetic Study.
    Title: TLR4, IgA and EpCAM Expression in Colorectal Cancer and Their Possible Association with Microbiota as a Pathogenic Factor; An Immunohistochemical and Genetic Study.
  2. Collagen IV and Podocyte-Related Gene Variants in Patients with Concurrent IgA Nephropathy and Thin Basement Membrane Nephropathy.
    Title: Collagen IV and Podocyte-Related Gene Variants in Patients with Concurrent IgA Nephropathy and Thin Basement Membrane Nephropathy.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
immunoglobulin heavy variable 4-38-2-like
Names
Ig heavy chain variable region (VDJ)
IgM rheumatoid factor immunoglobulin heavy chain
anti-SARS-CoV-2 immunoglobulin heavy chain variable region
anti-cardiolipin immunoglobulin heavy chain
anti-peanut 2S albumin immunoglobulin heavy chain variable region
anti-thrombospondin immunoglobulin heavy chain variable region
hybrid Ig/T-cell receptor precursor VH-DJ
immunglobulin heavy chain variable region
immunoglobulin E heavy chain variable region
immunoglobulin alpha heavy chain variable region
immunoglobulin heavy chain CDR3
immunoglobulin heavy chain variable region
immunoglobulin mu heavy chain variable region
immunoglobulin variable region
non-productive immunoglobulin heavy chain CDR3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NT_187381.1 Reference GRCh38.p14 Primary Assembly

    Range
    41382..43488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011546198.2 → XP_011544500.1  immunoglobulin heavy variable 4-38-2-like

    Conserved Domains (2) summary
    smart00410
    Location:33 → 123
    IG_like; Immunoglobulin like
    cl11960
    Location:30 → 125
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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