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GSK3B glycogen synthase kinase 3 beta [ Pan troglodytes (chimpanzee) ]

Gene ID: 100616510, updated on 29-Mar-2024

Summary

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Official Symbol
GSK3Bprovided by VGNC
Official Full Name
glycogen synthase kinase 3 betaprovided by VGNC
Primary source
VGNC:VGNC:11406
Locus tag
CK820_G0023889
See related
Ensembl:ENSPTRG00000015264
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (123125881..123398322, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (123039975..123307699, complement)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107970736 Neighboring gene cilia and flagella associated protein 91 Neighboring gene prohibitin 1-like Neighboring gene nuclear receptor subfamily 1 group I member 2 Neighboring gene presenilin-associated rhomboid-like protein, mitochondrial Neighboring gene uncharacterized LOC134809471 Neighboring gene G protein-coupled receptor 156

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tau-protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of beta-catenin destruction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glycogen synthase kinase-3 beta
XP_016797209.1
XP_016797210.1
XP_016797211.1
XP_016797213.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    123125881..123398322 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016941724.4 → XP_016797213.1  glycogen synthase kinase-3 beta isoform X4

    UniProtKB/TrEMBL
    A0A2I3S1U3
    Conserved Domains (1) summary
    cd14137
    Location:51 → 343
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  2. XM_016941721.3 → XP_016797210.1  glycogen synthase kinase-3 beta isoform X2

    UniProtKB/TrEMBL
    A0A2I3SXI2, A0A2J8M3L0, A0A6D2WIC6, K7CFX8
    Related
    ENSPTRP00000074940.1
    Conserved Domains (1) summary
    cd14137
    Location:51 → 343
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  3. XM_016941720.3 → XP_016797209.1  glycogen synthase kinase-3 beta isoform X1

    UniProtKB/TrEMBL
    A0A2I3SXI2, A0A2J8M3J6, A0A6D2XM46, H2QN60, K7CFE4
    Related
    ENSPTRP00000026315.5
    Conserved Domains (1) summary
    cd14137
    Location:51 → 356
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  4. XM_016941722.4 → XP_016797211.1  glycogen synthase kinase-3 beta isoform X3

    UniProtKB/TrEMBL
    A0A2I3S1U3
    Related
    ENSPTRP00000070918.1
    Conserved Domains (1) summary
    cd14137
    Location:51 → 356
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
Nucleotide Protein
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