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wnt7bb wingless-type MMTV integration site family, member 7Bb [ Danio rerio (zebrafish) ]

Gene ID: 100148840, updated on 11-Apr-2024

Summary

Official Symbol
wnt7bbprovided by ZNC
Official Full Name
wingless-type MMTV integration site family, member 7Bbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-081006-1
See related
Ensembl:ENSDARG00000071107 AllianceGenome:ZFIN:ZDB-GENE-081006-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wnt7b-like
Summary
Predicted to enable cytokine activity and frizzled binding activity. Predicted to be involved in several processes, including canonical Wnt signaling pathway; neuron differentiation; and positive regulation of JNK cascade. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain; midbrain neural rod; presumptive diencephalon; and presumptive telencephalon. Orthologous to human WNT7B (Wnt family member 7B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 25
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (2003183..2081346, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (1911947..1990124, complement)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 13 Neighboring gene fibulin 1 Neighboring gene si:ch211-218p2.3 Neighboring gene uncharacterized LOC101886390

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables frizzled binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell fate commitment IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of JNK cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within swim bladder formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in tissue development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    2003183..2081346 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017354279.2XP_017209768.1  protein Wnt-7b isoform X2

    UniProtKB/TrEMBL
    A0A8M6YYK6
  2. XM_001920184.7XP_001920219.1  protein Wnt-7b isoform X1

    UniProtKB/TrEMBL
    A0A8M1QHC7, X1WEJ5
    Related
    ENSDARP00000128646.1, ENSDART00000156925.3
    Conserved Domains (1) summary
    pfam00110
    Location:48352
    wnt; wnt family