| Entry |
|
|---|
| Name |
Aldosterone;
11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al
|
|---|
| Formula |
C21H28O5
|
|---|
| Exact mass |
360.1937
|
|---|
| Mol weight |
360.444
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Reaction |
|
|---|
| Pathway |
| map04925 | Aldosterone synthesis and secretion |
| map04960 | Aldosterone-regulated sodium reabsorption |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
|---|
| Module |
| M00108 | C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone |
|
|---|
| Network |
nt06019 Steroid hormone biosynthesis nt06310 CRH-ACTH-cortisol signaling nt06316 Renin-angiotensin-aldosterone signaling |
|---|
| Enzyme |
|
|---|
| Brite |
Compounds with biological roles [BR:br08001]
Steroids
21-Carbon atoms
Pregnane derivatives
C01780 Aldosterone
Hormones and transmitters
Steroid hormones
Mineralocorticoids
C01780 Aldosterone
Lipids [BR:br08002]
ST Sterol lipids
ST02 Steroids
ST0203 C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives
C01780 Aldosterone
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AA Mineralocorticoids
H02AA01 Aldosterone
D10528 Aldosterone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
D10528 Aldosterone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C2 (MR)
D10528 Aldosterone (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C1z C 27.5594 -21.6461
2 C1y C 27.5594 -23.0076
3 C1y C 28.7457 -20.9622
4 C1x C 26.3790 -20.9622
5 C4a C 27.5537 -20.2843
6 C1y C 26.3790 -23.6855
7 C1x C 29.9204 -23.0076
8 C1x C 29.9204 -21.6461
9 C5a C 28.7517 -19.5714
10 C1y C 25.1927 -21.6461
11 O4a O 26.3497 -19.5891
12 C1y C 25.1927 -23.0076
13 C1x C 26.3731 -25.0530
14 C1b C 29.9555 -18.8818
15 O5a O 27.5477 -18.8761
16 O1a O 24.0121 -20.9622
17 C1z C 24.0064 -23.6855
18 C1x C 25.1927 -25.7369
19 O1a O 31.1594 -19.5774
20 C2y C 24.0064 -25.0530
21 C1x C 22.8375 -23.0076
22 C1a C 23.9947 -22.3240
23 C2x C 22.8375 -25.7369
24 C1x C 21.6511 -23.6855
25 C5x C 21.6511 -25.0530
26 O5x O 20.4707 -25.7369
BOND 29
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 2
11 6 12 1
12 6 13 1
13 9 14 1
14 9 15 2
15 10 16 1 #Up
16 12 17 1
17 13 18 1
18 14 19 1
19 17 20 1
20 17 21 1
21 17 22 1 #Up
22 20 23 2
23 21 24 1
24 23 25 1
25 25 26 2
26 7 8 1
27 10 12 1
28 18 20 1
29 24 25 1
|
|---|
