KEGG   COMPOUND: C00064
Entry
C00064                      Compound                               
Name
L-Glutamine;
L-2-Aminoglutaramic acid
Formula
C5H10N2O3
Exact mass
146.0691
Mol weight
146.1445
Structure
Remark
Same as: D00015
Reaction
Pathway
map00220  Arginine biosynthesis
map00230  Purine metabolism
map00240  Pyrimidine metabolism
map00250  Alanine, aspartate and glutamate metabolism
map00470  D-Amino acid metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00750  Vitamin B6 metabolism
map00910  Nitrogen metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01230  Biosynthesis of amino acids
map01232  Nucleotide metabolism
map01240  Biosynthesis of cofactors
map02010  ABC transporters
map02020  Two-component system
map04724  Glutamatergic synapse
map04727  GABAergic synapse
map04964  Proximal tubule bicarbonate reclamation
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
M00916  Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P
Enzyme
1.4.1.13        1.4.1.14        1.4.7.1         2.3.1.14        
2.3.1.68        2.3.2.1         2.3.2.14        2.4.2.14        
2.6.1.15        2.6.1.16        2.6.1.50        2.6.1.64        
2.6.1.85        2.6.1.86        2.6.1.100       2.6.1.101       
2.6.1.117       2.6.1.123       2.7.3.13        3.5.1.2         
3.5.1.38        3.5.1.133       4.1.3.27        4.3.2.10        
4.3.3.6         5.1.1.10        6.1.1.18        6.3.1.2         
6.3.4.2         6.3.5.1         6.3.5.2         6.3.5.3         
6.3.5.4         6.3.5.5         6.3.5.6         6.3.5.7         
6.3.5.9         6.3.5.10        6.3.5.11        6.3.5.12        
6.3.5.13        6.3.5.-
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00064  Glutamine (Gln)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AA Amino acids and derivatives
     A16AA03 Glutamine
      D00015  Glutamine (USP) <JP/US>
USP drug classification [BR:br08302]
 Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
  Glutamine
   D00015  Glutamine (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   232  Peptic ulcer agents
    2322  Glutamines
     D00015  Glutamine (USP); L-Glutamine (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Glutamine
    D00015  Glutamine (USP)
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01975  Agents for peptic ulcer
   DG02008  Gastric mucosal protectant
    D00015  Glutamine
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00015  L-Glutamine
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D00015
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00015
Other DBs
CAS: 56-85-9
PubChem: 3364
ChEBI: 18050
KNApSAcK: C00001359
PDB-CCD: GLN[PDBj]
3DMET: B00017
NIKKAJI: J9.170G
LinkDB
KCF data

ATOM        10
            1   C1c C    23.8378  -17.4606
            2   C1b C    25.0254  -16.7178
            3   C6a C    22.6035  -16.7995
            4   N1a N    23.8787  -18.8587
            5   C1b C    26.2597  -17.3787
            6   O6a O    21.4451  -17.5952
            7   O6a O    22.6209  -15.4015
            8   C5a C    27.4472  -16.6416
            9   N1a N    28.6814  -17.3027
            10  O5a O    27.4704  -15.2435
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     8  10 2

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