AmiGO 2: Term Details for "cell surface receptor signaling pathway via STAT" (GO:0097696)

Term Information

Accession: GO:0097696
Name: cell surface receptor signaling pathway via STAT
Ontology: biological_process
Synonyms: STAT signalling pathway, kinase activated-STAT cascade, kinase-STAT cascade, receptor signaling pathway via STAT
Alternate IDs: None
Definition: An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins. Source: GOC:rjd, PMID:24587195, PMID:21534947
Comment: In most species, STAT proteins are activated by members of the JAK (Janus Activated Kinase) family of tyrosine kinases; the term GO:0007259 'JAK-STAT cascade' describes this specificity. In other cases, such as D. discoideum, no JAK orthologs are known, and STAT proteins are activated by tyrosine kinase-like proteins.
History: See term history for GO:0097696 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to cell surface receptor signaling pathway via STAT (excluding "regulates").; Link to all direct and indirect annotations to cell surface receptor signaling pathway via STAT (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cell surface receptor signaling pathway via STAT (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0050794 regulation of cellular process
GO:0023052 signaling
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0097696 cell surface receptor signaling pathway via STAT
GO:0007259 cell surface receptor signaling pathway via JAK-STAT
GO:1904893 negative regulation of receptor signaling pathway via STAT
GO:1904894 positive regulation of receptor signaling pathway via STAT
GO:1904892 regulation of receptor signaling pathway via STAT

Parents of cell surface receptor signaling pathway via STAT (GO:0097696)

subject	relation	object
cell surface receptor signaling pathway via STAT	is_a	cell surface receptor signaling pathway (GO:0007166)

Children of cell surface receptor signaling pathway via STAT (GO:0097696)

subject	relation	object
regulation of receptor signaling pathway via STAT (GO:1904892)	RO:0002211	cell surface receptor signaling pathway via STAT
negative regulation of receptor signaling pathway via STAT (GO:1904893)	RO:0002212	cell surface receptor signaling pathway via STAT
positive regulation of receptor signaling pathway via STAT (GO:1904894)	RO:0002213	cell surface receptor signaling pathway via STAT
cell surface receptor signaling pathway via JAK-STAT (GO:0007259)	is_a	cell surface receptor signaling pathway via STAT

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