AmiGO 2: Term Details for "execution phase of apoptosis" (GO:0097194)

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Term Information

Accession: GO:0097194
Name: execution phase of apoptosis
Ontology: biological_process
Synonyms: execution phase of apoptotic process, apoptosis
Alternate IDs: None
Definition: A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. Source: PMID:21760595, GOC:mtg_apoptosis
Comment: None
History: See term history for GO:0097194 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to execution phase of apoptosis (excluding "regulates").; Link to all direct and indirect annotations to execution phase of apoptosis (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for execution phase of apoptosis (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0009987 cellular process
GO:0008219 cell death
GO:0008150 biological_process
GO:0012501 programmed cell death
GO:0006915 apoptotic process
GO:0097194 execution phase of apoptosis
GO:0006921 cellular component disassembly involved in execution phase of apoptosis
GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1900118 negative regulation of execution phase of apoptosis
GO:0070782 phosphatidylserine exposure on apoptotic cell surface
GO:1900119 positive regulation of execution phase of apoptosis
GO:1900117 regulation of execution phase of apoptosis

Parents of execution phase of apoptosis (GO:0097194)

subject	relation	object
execution phase of apoptosis	BFO:0000051	bleb assembly (GO:0032060)
execution phase of apoptosis	is_a	cellular process (GO:0009987)
execution phase of apoptosis	RO:0002162	Opisthokonta (NCBITaxon:33154)
execution phase of apoptosis	BFO:0000050	apoptotic process (GO:0006915)

Children of execution phase of apoptosis (GO:0097194)

subject	relation	object
regulation of execution phase of apoptosis (GO:1900117)	RO:0002211	execution phase of apoptosis
negative regulation of execution phase of apoptosis (GO:1900118)	RO:0002212	execution phase of apoptosis
phosphatidylserine exposure on apoptotic cell surface (GO:0070782)	BFO:0000050	execution phase of apoptosis
cellular component disassembly involved in execution phase of apoptosis (GO:0006921)	BFO:0000050	execution phase of apoptosis
positive regulation of execution phase of apoptosis (GO:1900119)	RO:0002213	execution phase of apoptosis
apoptotic process (GO:0006915)	RO:0002230	execution phase of apoptosis
cysteine-type endopeptidase activity involved in execution phase of apoptosis (GO:0097200)	BFO:0000050	execution phase of apoptosis

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