AmiGO 2: Term Details for "error-free translesion synthesis" (GO:0070987)

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Term Information

Accession: GO:0070987
Name: error-free translesion synthesis
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level. Source: GOC:elh
Comment: Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication.
History: See term history for GO:0070987 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to error-free translesion synthesis (excluding "regulates").; Link to all direct and indirect annotations to error-free translesion synthesis (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for error-free translesion synthesis (excluding "regulates").

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0050896 response to stimulus
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0051716 cellular response to stimulus
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044238 primary metabolic process
GO:0006950 response to stress
GO:0044249 cellular biosynthetic process
GO:0033554 cellular response to stress
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0006974 DNA damage response
GO:0006259 DNA metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0071897 DNA biosynthetic process
GO:0006281 DNA repair
GO:0000731 DNA synthesis involved in DNA repair
GO:0006301 postreplication repair
GO:0019985 translesion synthesis
GO:0070987 error-free translesion synthesis

Parents of error-free translesion synthesis (GO:0070987)

subject	relation	object
error-free translesion synthesis	is_a	translesion synthesis (GO:0019985)

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