AmiGO 2: Term Details for "intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" (GO:0042771)

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Term Information

Accession: GO:0042771
Name: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Ontology: biological_process
Synonyms: DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
Alternate IDs: None
Definition: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. Source: GOC:go_curators, GOC:mtg_apoptosis
Comment: None
History: See term history for GO:0042771 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (excluding "regulates").; Link to all direct and indirect annotations to intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
GO:0009987 cellular process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0008219 cell death
GO:0005575 cellular_component
GO:0050789 regulation of biological process
CL:0000000 cell
GO:0007154 cell communication
GO:0110165 cellular anatomical structure
GO:0051716 cellular response to stimulus
GO:0012501 programmed cell death
GO:0050794 regulation of cellular process
GO:0050896 response to stimulus
GO:0023052 signaling
GO:0006915 apoptotic process
GO:0005622 intracellular anatomical structure
GO:0006950 response to stress
GO:0007165 signal transduction
GO:0097190 apoptotic signaling pathway
GO:0033554 cellular response to stress
GO:0035556 intracellular signal transduction
GO:0006974 DNA damage response
GO:0097193 intrinsic apoptotic signaling pathway
GO:0072331 signal transduction by p53 class mediator
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Parents of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)

subject	relation	object
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	RO:0002162	Eumetazoa (NCBITaxon:6072)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	is_a	intrinsic apoptotic signaling pathway in response to DNA damage (GO:0008630)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	is_a	intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332)

Children of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)

subject	relation	object
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902167)	RO:0002213	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902166)	RO:0002212	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902165)	RO:0002211	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

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