AmiGO 2: Term Details for "histone binding" (GO:0042393)

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Term Information

Accession: GO:0042393
Name: histone binding
Ontology: molecular_function
Synonyms: histone-specific chaperone activity
Alternate IDs: None
Definition: Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription. Source: PMID:9305837, PMID:16209651, GOC:jl, PMID:30212449
Comment: None
History: See term history for GO:0042393 at QuickGO
Chem. react.: None
Subset: goslim_drosophila; goslim_chembl; goslim_generic; goslim_yeast; goslim_prokaryote
Related: Link to all genes and gene products annotated to histone binding (excluding "regulates").; Link to all direct and indirect annotations to histone binding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for histone binding (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
GO:0042393 histone binding
GO:0070577 lysine-acetylated histone binding
GO:0035064 methylated histone binding
GO:0106153 phosphorylated histone binding

Parents of histone binding (GO:0042393)

subject	relation	object
histone binding	is_a	protein binding (GO:0005515)
histone binding	RO:0004009	histone (CHEBI:15358)

Children of histone binding (GO:0042393)

subject	relation	object
histone reader activity (GO:0140566)	BFO:0000051	histone binding
histone chaperone activity (GO:0140713)	BFO:0000051	histone binding
phosphorylated histone binding (GO:0106153)	is_a	histone binding
methylated histone binding (GO:0035064)	is_a	histone binding
lysine-acetylated histone binding (GO:0070577)	is_a	histone binding

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