AmiGO 2: Term Details for "Cajal body" (GO:0015030)

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Term Information

Accession: GO:0015030
Name: Cajal body
Ontology: cellular_component
Synonyms: coiled body, Gemini of coiled bodies, Gems
Alternate IDs: None
Definition: A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. Source: PMID:11031238, PMID:10944589, PMID:7559785, NIF_Subcellular:nlx_subcell_090901
Comment: None
History: See term history for GO:0015030 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Cajal body (excluding "regulates").; Link to all direct and indirect annotations to Cajal body (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Cajal body (excluding "regulates").

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UBERON:0000061 anatomical structure
CARO:0030000 biological entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0043226 organelle
CARO:0000000 anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0031974 membrane-enclosed lumen
UBERON:0001062 anatomical entity
GO:0043231 intracellular membrane-bounded organelle
CARO:0000006 material anatomical entity
GO:0043233 organelle lumen
CARO:0000003 connected anatomical structure
GO:0070013 intracellular organelle lumen
UBERON:0000465 material anatomical entity
GO:0005634 nucleus
GO:0005575 cellular_component
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0016604 nuclear body
GO:0015030 Cajal body
GO:0072589 box H/ACA scaRNP complex

Parents of Cajal body (GO:0015030)

subject	relation	object
Cajal body	is_a	nuclear body (GO:0016604)

Children of Cajal body (GO:0015030)

subject	relation	object
protein localization to Cajal body (GO:1904867)	RO:0002339	Cajal body
Cajal body organization (GO:0030576)	RO:0002592	Cajal body
box H/ACA scaRNP complex (GO:0072589)	BFO:0000050	Cajal body
RNA localization to Cajal body (GO:0090670)	RO:0002339	Cajal body

NIF_Subcellular: nlx_subcell_090901
Wikipedia: Cajal_body