AmiGO 2: Term Details for "COP9 signalosome" (GO:0008180)

Accession: GO:0008180
Name: COP9 signalosome
Ontology: cellular_component
Synonyms: COP9 complex, CSN, signalosome
Alternate IDs: None
Definition: A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. Source: PMID:12186635, PMID:14570571, PMID:11019806
Comment: None
History: See term history for GO:0008180 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to COP9 signalosome (excluding "regulates").; Link to all direct and indirect annotations to COP9 signalosome (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for COP9 signalosome (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
COP9 signalosome	is_a	nuclear protein-containing complex (GO:0140513)
COP9 signalosome	RO:0002215	protein deneddylation (GO:0000338)
COP9 signalosome	RO:0002162	Eukaryota (NCBITaxon:2759)

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