AmiGO 2: Term Details for "COP9 signalosome" (GO:0008180)

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Term Information

Accession: GO:0008180
Name: COP9 signalosome
Ontology: cellular_component
Synonyms: COP9 complex, CSN, signalosome
Alternate IDs: None
Definition: A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. Source: PMID:12186635, PMID:14570571, PMID:11019806
Comment: None
History: See term history for GO:0008180 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to COP9 signalosome (excluding "regulates").; Link to all direct and indirect annotations to COP9 signalosome (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for COP9 signalosome (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0008152 metabolic process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0071704 organic substance metabolic process
UBERON:0000061 anatomical structure
GO:0005575 cellular_component
GO:0043170 macromolecule metabolic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0043412 macromolecule modification
GO:0019538 protein metabolic process
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0036211 protein modification process
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0043687 post-translational protein modification
GO:0043231 intracellular membrane-bounded organelle
GO:0070647 protein modification by small protein conjugation or removal
PR:000050567 protein-containing material entity
GO:0005634 nucleus
GO:0070646 protein modification by small protein removal
GO:0032991 protein-containing complex
GO:0140513 nuclear protein-containing complex
GO:0000338 protein deneddylation
GO:0008180 COP9 signalosome

Parents of COP9 signalosome (GO:0008180)

subject	relation	object
COP9 signalosome	RO:0002215	protein deneddylation (GO:0000338)
COP9 signalosome	is_a	nuclear protein-containing complex (GO:0140513)

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