AmiGO 2: Term Details for "eukaryotic translation initiation factor 2B complex" (GO:0005851)

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Term Information

Accession: GO:0005851
Name: eukaryotic translation initiation factor 2B complex
Ontology: cellular_component
Synonyms: eIF-2B, eif2B
Alternate IDs: None
Definition: A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon. Source: PMID:9438375
Comment: None
History: See term history for GO:0005851 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to eukaryotic translation initiation factor 2B complex (excluding "regulates").; Link to all direct and indirect annotations to eukaryotic translation initiation factor 2B complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for eukaryotic translation initiation factor 2B complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
GO:0003674 molecular_function
CARO:0000000 anatomical entity
GO:0098772 molecular function regulator activity
UBERON:0001062 anatomical entity
GO:0030234 enzyme regulator activity
CARO:0000006 material anatomical entity
UBERON:0000061 anatomical structure
GO:0005575 cellular_component
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0060589 nucleoside-triphosphatase regulator activity
CL:0000000 cell
GO:0110165 cellular anatomical structure
GO:0030695 GTPase regulator activity
GO:0032991 protein-containing complex
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005622 intracellular anatomical structure
GO:0140535 intracellular protein-containing complex
GO:0005737 cytoplasm
GO:0032045 guanyl-nucleotide exchange factor complex
GO:0005851 eukaryotic translation initiation factor 2B complex

Parents of eukaryotic translation initiation factor 2B complex (GO:0005851)

subject	relation	object
eukaryotic translation initiation factor 2B complex	BFO:0000050	cytoplasm (GO:0005737)
eukaryotic translation initiation factor 2B complex	is_a	guanyl-nucleotide exchange factor complex (GO:0032045)
eukaryotic translation initiation factor 2B complex	RO:0002162	Eukaryota (NCBITaxon:2759)

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