Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

Configure this page

Share this page

Bookmark this page

.

Gene: PSEN2 ENSPTRG00000002052

.

Description

presenilin 2 [Source:VGNC Symbol;Acc:VGNC:1474]

Location

Chromosome 1: 205,919,664-205,945,445 forward strand.

Pan_tro_3.0:CM000314.3

About this gene

This gene has 3 transcripts (splice variants), 205 orthologues and 1 paralogue.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSPTRT00000058137.4	PSEN2-203	1458	485aa	ENSPTRP00000051089.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	H2R821	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical,
ENSPTRT00000089414.1	PSEN2-201	2558	448aa	ENSPTRP00000081085.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3SVT3 A0A6D2VWH0	APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,
ENSPTRT00000103545.1	PSEN2-202	2337	447aa	ENSPTRP00000076556.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3SHN4 A0A6D2WI11	APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,

.

Summary

.

.