dbSNP Short Genetic Variations
Welcome to the Reference SNP (rs) Report
All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.
Reference SNP (rs) Report
This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.
rs53576
Current Build 156
Released September 21, 2022
- Organism
- Homo sapiens
- Position
-
chr3:8762685 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
- Alleles
- A>G / A>T
- Variation Type
- SNV Single Nucleotide Variation
- Frequency
-
A=0.306872 (81226/264690, TOPMED)A=0.309437 (43359/140122, GnomAD)A=0.32646 (24474/74968, ALFA) (+ 18 more)
- Clinical Significance
- Not Reported in ClinVar
- Gene : Consequence
- OXTR : Intron Variant
- Publications
- 234 citations
- Genomic View
- See rs on genome
ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.
Release Version: 20230706150541
| Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|
| Total | Global | 74968 | A=0.32646 | G=0.67354, T=0.00000 |
| European | Sub | 62252 | A=0.32577 | G=0.67423, T=0.00000 |
| African | Sub | 4144 | A=0.2379 | G=0.7621, T=0.0000 |
| African Others | Sub | 154 | A=0.214 | G=0.786, T=0.000 |
| African American | Sub | 3990 | A=0.2388 | G=0.7612, T=0.0000 |
| Asian | Sub | 188 | A=0.559 | G=0.441, T=0.000 |
| East Asian | Sub | 148 | A=0.581 | G=0.419, T=0.000 |
| Other Asian | Sub | 40 | A=0.47 | G=0.53, T=0.00 |
| Latin American 1 | Sub | 242 | A=0.256 | G=0.744, T=0.000 |
| Latin American 2 | Sub | 1236 | A=0.3657 | G=0.6343, T=0.0000 |
| South Asian | Sub | 4932 | A=0.3944 | G=0.6056, T=0.0000 |
| Other | Sub | 1974 | A=0.3262 | G=0.6738, T=0.0000 |
Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").
Download| Study | Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| TopMed | Global | Study-wide | 264690 | A=0.306872 | G=0.693128 |
| gnomAD - Genomes | Global | Study-wide | 140122 | A=0.309437 | G=0.690563 |
| gnomAD - Genomes | European | Sub | 75880 | A=0.33861 | G=0.66139 |
| gnomAD - Genomes | African | Sub | 41998 | A=0.22013 | G=0.77987 |
| gnomAD - Genomes | American | Sub | 13648 | A=0.34525 | G=0.65475 |
| gnomAD - Genomes | Ashkenazi Jewish | Sub | 3316 | A=0.2952 | G=0.7048 |
| gnomAD - Genomes | East Asian | Sub | 3128 | A=0.6541 | G=0.3459 |
| gnomAD - Genomes | Other | Sub | 2152 | A=0.3174 | G=0.6826 |
| Allele Frequency Aggregator | Total | Global | 74968 | A=0.32646 | G=0.67354, T=0.00000 |
| Allele Frequency Aggregator | European | Sub | 62252 | A=0.32577 | G=0.67423, T=0.00000 |
| Allele Frequency Aggregator | South Asian | Sub | 4932 | A=0.3944 | G=0.6056, T=0.0000 |
| Allele Frequency Aggregator | African | Sub | 4144 | A=0.2379 | G=0.7621, T=0.0000 |
| Allele Frequency Aggregator | Other | Sub | 1974 | A=0.3262 | G=0.6738, T=0.0000 |
| Allele Frequency Aggregator | Latin American 2 | Sub | 1236 | A=0.3657 | G=0.6343, T=0.0000 |
| Allele Frequency Aggregator | Latin American 1 | Sub | 242 | A=0.256 | G=0.744, T=0.000 |
| Allele Frequency Aggregator | Asian | Sub | 188 | A=0.559 | G=0.441, T=0.000 |
| 14KJPN | JAPANESE | Study-wide | 28258 | A=0.62658 | G=0.37342 |
| 8.3KJPN | JAPANESE | Study-wide | 16760 | A=0.62452 | G=0.37548 |
| 1000Genomes_30x | Global | Study-wide | 6404 | A=0.3784 | G=0.6216 |
| 1000Genomes_30x | African | Sub | 1786 | A=0.1870 | G=0.8130 |
| 1000Genomes_30x | Europe | Sub | 1266 | A=0.3428 | G=0.6572 |
| 1000Genomes_30x | South Asian | Sub | 1202 | A=0.4476 | G=0.5524 |
| 1000Genomes_30x | East Asian | Sub | 1170 | A=0.6573 | G=0.3427 |
| 1000Genomes_30x | American | Sub | 980 | A=0.355 | G=0.645 |
| 1000Genomes | Global | Study-wide | 5008 | A=0.3894 | G=0.6106 |
| 1000Genomes | African | Sub | 1322 | A=0.1936 | G=0.8064 |
| 1000Genomes | East Asian | Sub | 1008 | A=0.6498 | G=0.3502 |
| 1000Genomes | Europe | Sub | 1006 | A=0.3509 | G=0.6491 |
| 1000Genomes | South Asian | Sub | 978 | A=0.449 | G=0.551 |
| 1000Genomes | American | Sub | 694 | A=0.356 | G=0.644 |
| Genetic variation in the Estonian population | Estonian | Study-wide | 4480 | A=0.3641 | G=0.6359 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | A=0.3238 | G=0.6762 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | A=0.3223 | G=0.6777 |
| KOREAN population from KRGDB | KOREAN | Study-wide | 2930 | A=0.6628 | G=0.3372, T=0.0000 |
| Genome of the Netherlands Release 5 | Genome of the Netherlands | Study-wide | 998 | A=0.343 | G=0.657 |
| CNV burdens in cranial meningiomas | Global | Study-wide | 788 | A=0.687 | G=0.313 |
| CNV burdens in cranial meningiomas | CRM | Sub | 788 | A=0.687 | G=0.313 |
| Northern Sweden | ACPOP | Study-wide | 600 | A=0.340 | G=0.660 |
| SGDP_PRJ | Global | Study-wide | 426 | A=0.282 | G=0.718 |
| Qatari | Global | Study-wide | 216 | A=0.324 | G=0.676 |
| A Vietnamese Genetic Variation Database | Global | Study-wide | 216 | A=0.690 | G=0.310 |
| The Danish reference pan genome | Danish | Study-wide | 40 | A=0.35 | G=0.65 |
| Siberian | Global | Study-wide | 36 | A=0.36 | G=0.64 |
| Ancient Sardinia genome-wide 1240k capture data generation and analysis | Global | Study-wide | 28 | A=0.50 | G=0.50 |
Help
Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.
Genomic Placements
| Sequence name | Change |
|---|---|
| GRCh38.p14 chr 3 | NC_000003.12:g.8762685A>G |
| GRCh38.p14 chr 3 | NC_000003.12:g.8762685A>T |
| GRCh37.p13 chr 3 | NC_000003.11:g.8804371A>G |
| GRCh37.p13 chr 3 | NC_000003.11:g.8804371A>T |
| CAV3 RefSeqGene (LRG_329) | NG_008797.2:g.33876A>G |
| CAV3 RefSeqGene (LRG_329) | NG_008797.2:g.33876A>T |
Gene: OXTR, oxytocin receptor
(minus strand)
| Molecule type | Change | Amino acid[Codon] | SO Term |
|---|---|---|---|
| OXTR transcript variant 1 | NM_000916.4:c.922+4581T>C | N/A | Intron Variant |
| OXTR transcript variant 2 |
NM_001354653.2:c.922+4581… NM_001354653.2:c.922+4581T>C |
N/A | Intron Variant |
| OXTR transcript variant 3 |
NM_001354654.2:c.922+4581… NM_001354654.2:c.922+4581T>C |
N/A | Intron Variant |
| OXTR transcript variant 4 |
NM_001354655.2:c.922+4581… NM_001354655.2:c.922+4581T>C |
N/A | Intron Variant |
| OXTR transcript variant 5 |
NM_001354656.3:c.922+4581… NM_001354656.3:c.922+4581T>C |
N/A | Intron Variant |
| OXTR transcript variant X1 | XR_007095681.1:n. | N/A | Intron Variant |
Help
Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.
Not Reported in ClinVar
Help
Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".
| Placement | A= | G | T |
|---|---|---|---|
| GRCh38.p14 chr 3 | NC_000003.12:g.8762685= | NC_000003.12:g.8762685A>G | NC_000003.12:g.8762685A>T |
| GRCh37.p13 chr 3 | NC_000003.11:g.8804371= | NC_000003.11:g.8804371A>G | NC_000003.11:g.8804371A>T |
| CAV3 RefSeqGene (LRG_329) | NG_008797.2:g.33876= | NG_008797.2:g.33876A>G | NG_008797.2:g.33876A>T |
| OXTR transcript variant 1 | NM_000916.3:c.922+4581= | NM_000916.3:c.922+4581T>C | NM_000916.3:c.922+4581T>A |
| OXTR transcript variant 1 | NM_000916.4:c.922+4581= | NM_000916.4:c.922+4581T>C | NM_000916.4:c.922+4581T>A |
| OXTR transcript variant 2 | NM_001354653.2:c.922+4581= | NM_001354653.2:c.922+4581T>C | NM_001354653.2:c.922+4581T>A |
| OXTR transcript variant 3 | NM_001354654.2:c.922+4581= | NM_001354654.2:c.922+4581T>C | NM_001354654.2:c.922+4581T>A |
| OXTR transcript variant 4 | NM_001354655.2:c.922+4581= | NM_001354655.2:c.922+4581T>C | NM_001354655.2:c.922+4581T>A |
| OXTR transcript variant 5 | NM_001354656.3:c.922+4581= | NM_001354656.3:c.922+4581T>C | NM_001354656.3:c.922+4581T>A |
Help
Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.
103 SubSNP,
20 Frequency
submissions
| No | Submitter | Submission ID | Date (Build) |
|---|---|---|---|
| 1 | TSC-CSHL | ss59712 | Oct 04, 2000 (86) |
| 2 | KWOK | ss306658 | Jul 10, 2000 (79) |
| 3 | KWOK | ss439098 | Jul 12, 2000 (87) |
| 4 | SC_JCM | ss528564 | Jul 16, 2000 (87) |
| 5 | KWOK | ss1014572 | Oct 04, 2000 (86) |
| 6 | KWOK | ss1055347 | Oct 04, 2000 (86) |
| 7 | KWOK | ss1652914 | Oct 18, 2000 (87) |
| 8 | SC_JCM | ss5673592 | Feb 20, 2003 (111) |
| 9 | BCM_SSAHASNP | ss14183444 | Dec 05, 2003 (119) |
| 10 | CSHL-HAPMAP | ss16948813 | Feb 27, 2004 (120) |
| 11 | SSAHASNP | ss21950419 | Apr 05, 2004 (121) |
| 12 | ABI | ss44461127 | Mar 13, 2006 (126) |
| 13 | PERLEGEN | ss46541669 | Mar 13, 2006 (126) |
| 14 | RIKENSNPRC | ss49848815 | Mar 13, 2006 (126) |
| 15 | HGSV | ss78851103 | Dec 07, 2007 (129) |
| 16 | HGSV | ss84951144 | Dec 16, 2007 (130) |
| 17 | BCMHGSC_JDW | ss91992564 | Mar 24, 2008 (129) |
| 18 | HUMANGENOME_JCVI | ss99074608 | Feb 06, 2009 (130) |
| 19 | BGI | ss103897889 | Dec 01, 2009 (131) |
| 20 | 1000GENOMES | ss111225319 | Jan 25, 2009 (130) |
| 21 | 1000GENOMES | ss112052328 | Jan 25, 2009 (130) |
| 22 | ILLUMINA-UK | ss116967912 | Feb 14, 2009 (130) |
| 23 | ENSEMBL | ss135225564 | Dec 01, 2009 (131) |
| 24 | ENSEMBL | ss138713663 | Dec 01, 2009 (131) |
| 25 | ILLUMINA | ss154337722 | Dec 01, 2009 (131) |
| 26 | GMI | ss155083237 | Dec 01, 2009 (131) |
| 27 | ILLUMINA | ss159514304 | Dec 01, 2009 (131) |
| 28 | COMPLETE_GENOMICS | ss161915046 | Jul 04, 2010 (132) |
| 29 | COMPLETE_GENOMICS | ss163085984 | Jul 04, 2010 (132) |
| 30 | COMPLETE_GENOMICS | ss166129391 | Jul 04, 2010 (132) |
| 31 | ILLUMINA | ss173915915 | Jul 04, 2010 (132) |
| 32 | BUSHMAN | ss202109412 | Jul 04, 2010 (132) |
| 33 | BCM-HGSC-SUB | ss206134681 | Jul 04, 2010 (132) |
| 34 | 1000GENOMES | ss219970775 | Jul 14, 2010 (132) |
| 35 | 1000GENOMES | ss231700317 | Jul 14, 2010 (132) |
| 36 | 1000GENOMES | ss239135799 | Jul 15, 2010 (132) |
| 37 | BL | ss252921855 | May 09, 2011 (134) |
| 38 | GMI | ss277006576 | May 04, 2012 (137) |
| 39 | GMI | ss284591708 | Apr 25, 2013 (138) |
| 40 | PJP | ss292858691 | May 09, 2011 (134) |
| 41 | ILLUMINA | ss479382349 | May 04, 2012 (137) |
| 42 | ILLUMINA | ss484649902 | May 04, 2012 (137) |
| 43 | ILLUMINA | ss532941640 | Sep 08, 2015 (146) |
| 44 | TISHKOFF | ss556413349 | Apr 25, 2013 (138) |
| 45 | SSMP | ss650078333 | Apr 25, 2013 (138) |
| 46 | ILLUMINA | ss779576289 | Sep 08, 2015 (146) |
| 47 | ILLUMINA | ss780967562 | Sep 08, 2015 (146) |
| 48 | ILLUMINA | ss833025600 | Jul 13, 2019 (153) |
| 49 | ILLUMINA | ss835047738 | Sep 08, 2015 (146) |
| 50 | EVA-GONL | ss978252171 | Aug 21, 2014 (142) |
| 51 | JMKIDD_LAB | ss1070160726 | Aug 21, 2014 (142) |
| 52 | 1000GENOMES | ss1302725027 | Aug 21, 2014 (142) |
| 53 | DDI | ss1429324856 | Apr 01, 2015 (144) |
| 54 | EVA_GENOME_DK | ss1579837623 | Apr 01, 2015 (144) |
| 55 | EVA_DECODE | ss1587712276 | Apr 01, 2015 (144) |
| 56 | EVA_UK10K_ALSPAC | ss1606373064 | Apr 01, 2015 (144) |
| 57 | EVA_UK10K_TWINSUK | ss1649367097 | Apr 01, 2015 (144) |
| 58 | HAMMER_LAB | ss1798826805 | Sep 08, 2015 (146) |
| 59 | WEILL_CORNELL_DGM | ss1921503730 | Feb 12, 2016 (147) |
| 60 | GENOMED | ss1969318795 | Jul 19, 2016 (147) |
| 61 | JJLAB | ss2021304681 | Sep 14, 2016 (149) |
| 62 | USC_VALOUEV | ss2149371904 | Dec 20, 2016 (150) |
| 63 | HUMAN_LONGEVITY | ss2248922741 | Dec 20, 2016 (150) |
| 64 | SYSTEMSBIOZJU | ss2625152856 | Nov 08, 2017 (151) |
| 65 | ILLUMINA | ss2633908611 | Nov 08, 2017 (151) |
| 66 | GRF | ss2704730737 | Nov 08, 2017 (151) |
| 67 | GNOMAD | ss2789316395 | Nov 08, 2017 (151) |
| 68 | AFFY | ss2985865383 | Nov 08, 2017 (151) |
| 69 | SWEGEN | ss2991798893 | Nov 08, 2017 (151) |
| 70 | BIOINF_KMB_FNS_UNIBA | ss3024415283 | Nov 08, 2017 (151) |
| 71 | CSHL | ss3344875995 | Nov 08, 2017 (151) |
| 72 | ILLUMINA | ss3628585015 | Oct 11, 2018 (152) |
| 73 | ILLUMINA | ss3631857441 | Oct 11, 2018 (152) |
| 74 | ILLUMINA | ss3638395767 | Oct 11, 2018 (152) |
| 75 | ILLUMINA | ss3642232861 | Oct 11, 2018 (152) |
| 76 | URBANLAB | ss3647336470 | Oct 11, 2018 (152) |
| 77 | EGCUT_WGS | ss3659698815 | Jul 13, 2019 (153) |
| 78 | EVA_DECODE | ss3708598227 | Jul 13, 2019 (153) |
| 79 | ACPOP | ss3729615751 | Jul 13, 2019 (153) |
| 80 | EVA | ss3759636198 | Jul 13, 2019 (153) |
| 81 | PACBIO | ss3784229979 | Jul 13, 2019 (153) |
| 82 | PACBIO | ss3789759450 | Jul 13, 2019 (153) |
| 83 | PACBIO | ss3794633193 | Jul 13, 2019 (153) |
| 84 | KHV_HUMAN_GENOMES | ss3802787969 | Jul 13, 2019 (153) |
| 85 | EVA | ss3827651703 | Apr 25, 2020 (154) |
| 86 | SGDP_PRJ | ss3855186553 | Apr 25, 2020 (154) |
| 87 | KRGDB | ss3900953568 | Apr 25, 2020 (154) |
| 88 | EVA | ss3984502600 | Apr 26, 2021 (155) |
| 89 | EVA | ss3984971607 | Apr 26, 2021 (155) |
| 90 | TOPMED | ss4553568730 | Apr 26, 2021 (155) |
| 91 | TOMMO_GENOMICS | ss5157709959 | Apr 26, 2021 (155) |
| 92 | 1000G_HIGH_COVERAGE | ss5252981028 | Oct 13, 2022 (156) |
| 93 | EVA | ss5314831936 | Oct 13, 2022 (156) |
| 94 | EVA | ss5337766837 | Oct 13, 2022 (156) |
| 95 | HUGCELL_USP | ss5452489490 | Oct 13, 2022 (156) |
| 96 | 1000G_HIGH_COVERAGE | ss5530780795 | Oct 13, 2022 (156) |
| 97 | SANFORD_IMAGENETICS | ss5631504633 | Oct 13, 2022 (156) |
| 98 | TOMMO_GENOMICS | ss5688951462 | Oct 13, 2022 (156) |
| 99 | YY_MCH | ss5803464059 | Oct 13, 2022 (156) |
| 100 | EVA | ss5825319992 | Oct 13, 2022 (156) |
| 101 | EVA | ss5853482349 | Oct 13, 2022 (156) |
| 102 | EVA | ss5867551703 | Oct 13, 2022 (156) |
| 103 | EVA | ss5959762353 | Oct 13, 2022 (156) |
| 104 | 1000Genomes | NC_000003.11 - 8804371 | Oct 11, 2018 (152) |
| 105 | 1000Genomes_30x | NC_000003.12 - 8762685 | Oct 13, 2022 (156) |
| 106 | The Avon Longitudinal Study of Parents and Children | NC_000003.11 - 8804371 | Oct 11, 2018 (152) |
| 107 | Genetic variation in the Estonian population | NC_000003.11 - 8804371 | Oct 11, 2018 (152) |
| 108 | The Danish reference pan genome | NC_000003.11 - 8804371 | Apr 25, 2020 (154) |
| 109 | gnomAD - Genomes | NC_000003.12 - 8762685 | Apr 26, 2021 (155) |
| 110 | Genome of the Netherlands Release 5 | NC_000003.11 - 8804371 | Apr 25, 2020 (154) |
| 111 | KOREAN population from KRGDB | NC_000003.11 - 8804371 | Apr 25, 2020 (154) |
| 112 | Northern Sweden | NC_000003.11 - 8804371 | Jul 13, 2019 (153) |
| 113 | Ancient Sardinia genome-wide 1240k capture data generation and analysis | NC_000003.11 - 8804371 | Apr 26, 2021 (155) |
| 114 | CNV burdens in cranial meningiomas | NC_000003.11 - 8804371 | Apr 26, 2021 (155) |
| 115 | Qatari | NC_000003.11 - 8804371 | Apr 25, 2020 (154) |
| 116 | SGDP_PRJ | NC_000003.11 - 8804371 | Apr 25, 2020 (154) |
| 117 | Siberian | NC_000003.11 - 8804371 | Apr 25, 2020 (154) |
| 118 | 8.3KJPN | NC_000003.11 - 8804371 | Apr 26, 2021 (155) |
| 119 | 14KJPN | NC_000003.12 - 8762685 | Oct 13, 2022 (156) |
| 120 | TopMed | NC_000003.12 - 8762685 | Apr 26, 2021 (155) |
| 121 | UK 10K study - Twins | NC_000003.11 - 8804371 | Oct 11, 2018 (152) |
| 122 | A Vietnamese Genetic Variation Database | NC_000003.11 - 8804371 | Jul 13, 2019 (153) |
| 123 | ALFA | NC_000003.12 - 8762685 | Apr 26, 2021 (155) |
Help
History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).
| Associated ID | History Updated (Build) |
|---|---|
| rs345116 | Oct 23, 2000 (87) |
| rs61493474 | May 26, 2008 (130) |
Added to this RefSNP Cluster:
| Submission IDs | Observation SPDI | Canonical SPDI | Source RSIDs |
|---|---|---|---|
| ss78851103, ss84951144 | NC_000003.9:8779370:A:G | NC_000003.12:8762684:A:G | (self) |
| ss91992564, ss111225319, ss112052328, ss116967912, ss161915046, ss163085984, ss166129391, ss202109412, ss206134681, ss252921855, ss277006576, ss284591708, ss292858691, ss484649902, ss1587712276 | NC_000003.10:8779370:A:G | NC_000003.12:8762684:A:G | (self) |
| 13867212, 7686154, 5437063, 6002562, 3375552, 8130962, 2900616, 197534, 51942, 3545660, 7203533, 1888258, 15679266, 7686154, 1673758, ss219970775, ss231700317, ss239135799, ss479382349, ss532941640, ss556413349, ss650078333, ss779576289, ss780967562, ss833025600, ss835047738, ss978252171, ss1070160726, ss1302725027, ss1429324856, ss1579837623, ss1606373064, ss1649367097, ss1798826805, ss1921503730, ss1969318795, ss2021304681, ss2149371904, ss2625152856, ss2633908611, ss2704730737, ss2789316395, ss2985865383, ss2991798893, ss3344875995, ss3628585015, ss3631857441, ss3638395767, ss3642232861, ss3659698815, ss3729615751, ss3759636198, ss3784229979, ss3789759450, ss3794633193, ss3827651703, ss3855186553, ss3900953568, ss3984502600, ss3984971607, ss5157709959, ss5314831936, ss5337766837, ss5631504633, ss5825319992, ss5959762353 | NC_000003.11:8804370:A:G | NC_000003.12:8762684:A:G | (self) |
| 18306730, 98487949, 22788566, 390946285, 8607225291, ss2248922741, ss3024415283, ss3647336470, ss3708598227, ss3802787969, ss4553568730, ss5252981028, ss5452489490, ss5530780795, ss5688951462, ss5803464059, ss5853482349, ss5867551703 | NC_000003.12:8762684:A:G | NC_000003.12:8762684:A:G | (self) |
| ss14183444, ss16948813, ss21950419 | NT_022517.16:8744370:A:G | NC_000003.12:8762684:A:G | (self) |
| ss59712, ss306658, ss439098, ss528564, ss1014572, ss1055347, ss1652914, ss5673592, ss44461127, ss46541669, ss49848815, ss99074608, ss103897889, ss135225564, ss138713663, ss154337722, ss155083237, ss159514304, ss173915915 | NT_022517.18:8744370:A:G | NC_000003.12:8762684:A:G | (self) |
| 8130962, ss3900953568 | NC_000003.11:8804370:A:T | NC_000003.12:8762684:A:T | (self) |
| 8607225291 | NC_000003.12:8762684:A:T | NC_000003.12:8762684:A:T | (self) |
Help
Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.
234
citations for rs53576
| PMID | Title | Author | Year | Journal |
|---|---|---|---|---|
| 15992526 | Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. | Wu S et al. | 2005 | Biological psychiatry |
| 17383819 | Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism. | Jacob S et al. | 2007 | Neuroscience letters |
| 18687882 | Genetic correlates of adult attachment style. | Gillath O et al. | 2008 | Personality & social psychology bulletin |
| 19015103 | Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting. | Bakermans-Kranenburg MJ et al. | 2008 | Social cognitive and affective neuroscience |
| 19376182 | Associations between the oxytocin receptor gene (OXTR) and affect, loneliness and intelligence in normal subjects. | Lucht MJ et al. | 2009 | Progress in neuro-psychopharmacology & biological psychiatry |
| 19515497 | Oxytocin receptor polymorphisms and adult attachment style in patients with depression. | Costa B et al. | 2009 | Psychoneuroendocrinology |
| 19934046 | Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans. | Rodrigues SM et al. | 2009 | Proceedings of the National Academy of Sciences of the United States of America |
| 20347913 | Evidence that genetic variation in the oxytocin receptor (OXTR) gene influences social cognition in ADHD. | Park J et al. | 2010 | Progress in neuro-psychopharmacology & biological psychiatry |
| 20585395 | No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences. | Apicella CL et al. | 2010 | PloS one |
| 20647384 | A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function. | Tost H et al. | 2010 | Proceedings of the National Academy of Sciences of the United States of America |
| 20724662 | Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking. | Kim HS et al. | 2010 | Proceedings of the National Academy of Sciences of the United States of America |
| 21484202 | Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder. | Campbell DB et al. | 2011 | Journal of neurodevelopmental disorders |
| 21749372 | Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects. | Luijk MP et al. | 2011 | Journal of child psychology and psychiatry, and allied disciplines |
| 21896752 | Oxytocin receptor gene (OXTR) is related to psychological resources. | Saphire-Bernstein S et al. | 2011 | Proceedings of the National Academy of Sciences of the United States of America |
| 22015110 | Variation in the oxytocin receptor gene is associated with pair-bonding and social behavior. | Walum H et al. | 2012 | Biological psychiatry |
| 22069391 | Oxytocin receptor gene associated with the efficiency of social auditory processing. | Tops M et al. | 2011 | Frontiers in psychiatry |
| 22084107 | Thin-slicing study of the oxytocin receptor (OXTR) gene and the evaluation and expression of the prosocial disposition. | Kogan A et al. | 2011 | Proceedings of the National Academy of Sciences of the United States of America |
| 22123970 | Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans. | Chen FS et al. | 2011 | Proceedings of the National Academy of Sciences of the United States of America |
| 22357335 | The association between oxytocin receptor gene polymorphism (OXTR) and trait empathy. | Wu N et al. | 2012 | Journal of affective disorders |
| 22372486 | The role of oxytocin and oxytocin receptor gene variants in childhood-onset aggression. | Malik AI et al. | 2012 | Genes, brain, and behavior |
| 22487732 | Influence of COX-2 and OXTR polymorphisms on treatment outcome in treatment resistant depression. | Mendlewicz J et al. | 2012 | Neuroscience letters |
| 22563705 | Differential susceptibility in spillover between interparental conflict and maternal parenting practices: evidence for OXTR and 5-HTT genes. | Sturge-Apple ML et al. | 2012 | Journal of family psychology |
| 22580735 | Breastfeeding and its relation to maternal sensitivity and infant attachment. | Tharner A et al. | 2012 | Journal of developmental and behavioral pediatrics |
| 22615702 | Imaging-genetics in autism spectrum disorder: advances, translational impact, and future directions. | Ameis SH et al. | 2012 | Frontiers in psychiatry |
| 22763666 | The influence of oxytocin administration on responses to infant faces and potential moderation by OXTR genotype. | Marsh AA et al. | 2012 | Psychopharmacology |
| 22809402 | Associations between the oxytocin receptor gene (OXTR) and "mind-reading" in humans--an exploratory study. | Lucht MJ et al. | 2013 | Nordic journal of psychiatry |
| 22846218 | Sexually dimorphic effects of oxytocin receptor gene (OXTR ) variants on Harm Avoidance. | Stankova T et al. | 2012 | Biology of sex differences |
| 22939719 | Oxytocin and catechol-O-methyltransferase receptor genotype predict the length of the first stage of labor. | Terkawi AS et al. | 2012 | American journal of obstetrics and gynecology |
| 23087634 | DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli. | Jack A et al. | 2012 | Frontiers in human neuroscience |
| 23089921 | Common oxytocin receptor gene polymorphisms and the risk for preterm birth. | Kuessel L et al. | 2013 | Disease markers |
| 23284802 | Association between oxytocin receptor gene polymorphisms and self-rated 'empathic concern' in schizophrenia. | Montag C et al. | 2012 | PloS one |
| 23335876 | Sex, receptors, and attachment: a review of individual factors influencing response to oxytocin. | Macdonald KS et al. | 2012 | Frontiers in neuroscience |
| 23562248 | The association between the oxytocin receptor gene (OXTR) and hypnotizability. | Bryant RA et al. | 2013 | Psychoneuroendocrinology |
| 23684879 | Variant in OXTR gene and functional connectivity of the hypothalamus in normal subjects. | Wang J et al. | 2013 | NeuroImage |
| 23708061 | Neural mechanisms of oxytocin receptor gene mediating anxiety-related temperament. | Wang J et al. | 2014 | Brain structure & function |
| 23921259 | A sociability gene? Meta-analysis of oxytocin receptor genotype effects in humans. | Bakermans-Kranenburg MJ et al. | 2014 | Psychiatric genetics |
| 24209975 | Are genetic variations in OXTR, AVPR1A, and CD38 genes important to social integration? Results from two large U.S. cohorts. | Chang SC et al. | 2014 | Psychoneuroendocrinology |
| 24295535 | Oxytocin receptor gene variation predicts empathic concern and autonomic arousal while perceiving harm to others. | Smith KE et al. | 2014 | Social neuroscience |
| 24596569 | Gene-environment interactions and intermediate phenotypes: early trauma and depression. | Hornung OP et al. | 2014 | Frontiers in endocrinology |
| 24621832 | Oxytocin receptor gene polymorphism, perceived social support, and psychological symptoms in maltreated adolescents. | Hostinar CE et al. | 2014 | Development and psychopathology |
| 24703166 | Oxytocin receptor gene polymorphism (rs53576) moderates the intergenerational transmission of depression. | Thompson SM et al. | 2014 | Psychoneuroendocrinology |
| 24749639 | Motherhood and oxytocin receptor genetic variation are associated with selective changes in electrocortical responses to infant facial expressions. | Peltola MJ et al. | 2014 | Emotion (Washington, D.C.) |
| 24768649 | Salivary oxytocin mediates the association between emotional maltreatment and responses to emotional infant faces. | Bhandari R et al. | 2014 | Physiology & behavior |
| 24814480 | Social cognition, face processing, and oxytocin receptor single nucleotide polymorphisms in typically developing children. | Slane MM et al. | 2014 | Developmental cognitive neuroscience |
| 25001970 | Oxytocin receptor gene rs53576 polymorphism modulates oxytocin-dopamine interaction and neuroticism traits--a SPECT study. | Chang WH et al. | 2014 | Psychoneuroendocrinology |
| 25003328 | Social stress and the oxytocin receptor gene interact to predict antisocial behavior in an at-risk cohort. | Smearman EL et al. | 2015 | Development and psychopathology |
| 25009457 | Social bonding: regulation by neuropeptides. | Lieberwirth C et al. | 2014 | Frontiers in neuroscience |
| 25092315 | Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder. | Parker KJ et al. | 2014 | Proceedings of the National Academy of Sciences of the United States of America |
| 25405348 | Oxytocin and vasopressin receptor gene variation as a proximate base for inter- and intraspecific behavioral differences in bonobos and chimpanzees. | Staes N et al. | 2014 | PloS one |
| 25450139 | Preliminary evidence for the interaction of the oxytocin receptor gene (oxtr) and face processing in differentiating prenatal smoking patterns. | Massey SH et al. | 2015 | Neuroscience letters |
| 25564674 | Distress of ostracism: oxytocin receptor gene polymorphism confers sensitivity to social exclusion. | McQuaid RJ et al. | 2015 | Social cognitive and affective neuroscience |
| 25622005 | Sensitivity in detecting facial displays of emotion: Impact of maternal depression and oxytocin receptor genotype. | Burkhouse KL et al. | 2016 | Cognition & emotion |
| 25637390 | Oxytocin receptor gene and racial ingroup bias in empathy-related brain activity. | Luo S et al. | 2015 | NeuroImage |
| 25640833 | Religion priming and an oxytocin receptor gene (OXTR) polymorphism interact to affect self-control in a social context. | Sasaki JY et al. | 2015 | Development and psychopathology |
| 25680993 | Interaction between oxytocin receptor polymorphism and interdependent culture values on human empathy. | Luo S et al. | 2015 | Social cognitive and affective neuroscience |
| 25773927 | Association between the oxytocin receptor gene polymorphism (rs53576) and bulimia nervosa. | Kim YR et al. | 2015 | European eating disorders review |
| 25890851 | Methylation of the oxytocin receptor gene in clinically depressed patients compared to controls: The role of OXTR rs53576 genotype. | Reiner I et al. | 2015 | Journal of psychiatric research |
| 25935637 | The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576). | Weisman O et al. | 2015 | Psychoneuroendocrinology |
| 26106053 | Severity of eating disorder symptoms related to oxytocin receptor polymorphisms in anorexia nervosa. | Acevedo SF et al. | 2015 | Psychiatry research |
| 26121678 | Association of Oxytocin Receptor Gene (OXTR) rs53576 Polymorphism with Sociality: A Meta-Analysis. | Li J et al. | 2015 | PloS one |
| 26174935 | Oxytocin system social function impacts in children with attention-deficit/hyperactivity disorder. | Ayaz AB et al. | 2015 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 26175754 | DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women. | Chagnon YC et al. | 2015 | Frontiers in genetics |
| 26178189 | A common oxytocin receptor gene (OXTR) polymorphism modulates intranasal oxytocin effects on the neural response to social cooperation in humans. | Feng C et al. | 2015 | Genes, brain, and behavior |
| 26184070 | Gene-set and multivariate genome-wide association analysis of oppositional defiant behavior subtypes in attention-deficit/hyperactivity disorder. | Aebi M et al. | 2016 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 26228411 | Examining gene-environment interactions in comorbid depressive and disruptive behavior disorders using a Bayesian approach. | Adrian M et al. | 2015 | Journal of psychiatric research |
| 26241486 | Common oxytocin receptor gene variant interacts with rejection sensitivity to influence cortisol reactivity during negative evaluation. | Auer BJ et al. | 2015 | Hormones and behavior |
| 26253726 | Primate paternal care: Interactions between biology and social experience. | Storey AE et al. | 2016 | Hormones and behavior |
| 26257770 | Interaction between oxytocin receptor DNA methylation and genotype is associated with risk of postpartum depression in women without depression in pregnancy. | Bell AF et al. | 2015 | Frontiers in genetics |
| 26321972 | The moderating role of an oxytocin receptor gene polymorphism in the relation between unsupportive social interactions and coping profiles: implications for depression. | McInnis OA et al. | 2015 | Frontiers in psychology |
| 26322220 | A comprehensive meta-analysis of common genetic variants in autism spectrum conditions. | Warrier V et al. | 2015 | Molecular autism |
| 26389606 | Genetic moderation of stability in attachment security from early childhood to age 18 years: A replication study. | Raby KL et al. | 2015 | Developmental psychology |
| 26392129 | Oxytocin Pathway Genes: Evolutionary Ancient System Impacting on Human Affiliation, Sociality, and Psychopathology. | Feldman R et al. | 2016 | Biological psychiatry |
| 26441708 | Hypothesis-driven research for G × E interactions: the relationship between oxytocin, parental divorce during adolescence, and depression in young adulthood. | Windle M et al. | 2015 | Frontiers in psychology |
| 26444016 | Polymorphism of the Oxytocin Receptor Gene Modulates Behavioral and Attitudinal Trust among Men but Not Women. | Nishina K et al. | 2015 | PloS one |
| 26488131 | Attachment style and oxytocin receptor gene variation interact in influencing social anxiety. | Notzon S et al. | 2016 | The world journal of biological psychiatry |
| 26506050 | Genetic modulation of oxytocin sensitivity: a pharmacogenetic approach. | Chen FS et al. | 2015 | Translational psychiatry |
| 26599592 | Lack of Association between Oxytocin Receptor (OXTR) Gene Polymorphisms and Alexithymia: Evidence from Patients with Obsessive-Compulsive Disorder. | Koh MJ et al. | 2015 | PloS one |
| 26713079 | Is Oxytocin Application for Autism Spectrum Disorder Evidence-Based? | Lee SY et al. | 2015 | Experimental neurobiology |
| 26738630 | Polymorphisms of two loci at the oxytocin receptor gene in populations of Africa, Asia and South Europe. | Butovskaya PR et al. | 2016 | BMC genetics |
| 26787430 | Oxytocin receptor gene variation predicts subjective responses to MDMA. | Bershad AK et al. | 2016 | Social neuroscience |
| 26857197 | Sleep duration, depression, and oxytocinergic genotype influence prepulse inhibition of the startle reflex in postpartum women. | Comasco E et al. | 2016 | European neuropsychopharmacology |
| 26858213 | Disadvantage of Social Sensitivity: Interaction of Oxytocin Receptor Genotype and Child Maltreatment on Brain Structure. | Dannlowski U et al. | 2016 | Biological psychiatry |
| 26858594 | Oxytocin and Vasopressin Receptor Gene Polymorphisms: Role in Social and Psychiatric Traits. | Aspé-Sánchez M et al. | 2015 | Frontiers in neuroscience |
| 26869977 | The Adapting Mind in the Genomic Era. | Fieder M et al. | 2016 | Frontiers in psychology |
| 26901829 | BDNF Val66Met Polymorphism Is Associated with Self-Reported Empathy. | Taschereau-Dumouchel V et al. | 2016 | PloS one |
| 26903384 | Oxytocin receptor gene polymorphism modulates the effects of social support on heart rate variability. | Kanthak MK et al. | 2016 | Biological psychology |
| 26903639 | Delay discounting, genetic sensitivity, and leukocyte telomere length. | Yim OS et al. | 2016 | Proceedings of the National Academy of Sciences of the United States of America |
| 26998571 | Oxytocin and parent-child interaction in the development of empathy among children at risk for autism. | McDonald NM et al. | 2016 | Developmental psychology |
| 27015428 | The Idea Is Good, but…: Failure to Replicate Associations of Oxytocinergic Polymorphisms with Face-Inversion in the N170. | Munk AJ et al. | 2016 | PloS one |
| 27036876 | An oxytocin receptor polymorphism predicts amygdala reactivity and antisocial behavior in men. | Waller R et al. | 2016 | Social cognitive and affective neuroscience |
| 27109357 | Oxytocin receptor polymorphism and childhood social experiences shape adult personality, brain structure and neural correlates of mentalizing. | Schneider-Hassloff H et al. | 2016 | NeuroImage |
| 27292275 | Youth temperament, harsh parenting, and variation in the oxytocin receptor gene forecast allostatic load during emerging adulthood. | Brody GH et al. | 2017 | Development and psychopathology |
| 27317929 | Effects of oxytocin administration on spirituality and emotional responses to meditation. | Van Cappellen P et al. | 2016 | Social cognitive and affective neuroscience |
| 27467763 | Association of a Common Oxytocin Receptor Gene Polymorphism with Self-Reported 'Empathic Concern' in a Large Population of Healthy Volunteers. | Huetter FK et al. | 2016 | PloS one |
| 27497314 | Variation in the oxytocin receptor gene (OXTR) is associated with differences in moral judgment. | Bernhard RM et al. | 2016 | Social cognitive and affective neuroscience |
| 27520745 | Prenatal stress exposure, oxytocin receptor gene (OXTR) methylation, and child autistic traits: The moderating role of OXTR rs53576 genotype. | Rijlaarsdam J et al. | 2017 | Autism research |
| 27552585 | Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial. | Kosaka H et al. | 2016 | Translational psychiatry |
| 27650102 | Implicit association to infant faces: Genetics, early care experiences, and cultural factors influence caregiving propensities. | Senese VP et al. | 2017 | Behavioural brain research |
| 27693815 | Congenital prosopagnosia is associated with a genetic variation in the oxytocin receptor (OXTR) gene: An exploratory study. | Cattaneo Z et al. | 2016 | Neuroscience |
| 27713694 | Variation in the Oxytocin Receptor Gene Is Associated with Face Recognition and its Neural Correlates. | Westberg L et al. | 2016 | Frontiers in behavioral neuroscience |
| 27766960 | Spontaneous preterm birth and single nucleotide gene polymorphisms: a recent update. | Sheikh IA et al. | 2016 | BMC genomics |
| 27818356 | Association between oxytocin and receptor genetic polymorphisms and aggression in a northern Chinese Han population with alcohol dependence. | Yang L et al. | 2017 | Neuroscience letters |
| 27842184 | Socioeconomic Disparities in Childhood Obesity Risk: Association With an Oxytocin Receptor Polymorphism. | Bush NR et al. | 2017 | JAMA pediatrics |
| 27847593 | Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders. | Haram M et al. | 2016 | BJPsych open |
| 27862641 | Association Between Oxytocin Receptor Genotype, Maternal Care, and Eating Disorder Behaviours in a Community Sample of Women. | Micali N et al. | 2017 | European eating disorders review |
| 27872764 | Genetic Regulation of Maternal Oxytocin Response and Its Influences on Maternal Behavior. | Mehta D et al. | 2016 | Neural plasticity |
| 27920663 | ASD and Genetic Associations with Receptors for Oxytocin and Vasopressin-AVPR1A, AVPR1B, and OXTR. | Francis SM et al. | 2016 | Frontiers in neuroscience |
| 28069897 | Impact of estrogen receptor α gene and oxytocin receptor gene polymorphisms on female sexuality. | Armeni AK et al. | 2017 | Endocrine connections |
| 28126018 | Associations between the oxytocin receptor gene (OXTR) rs53576 polymorphism and emotional processing of social and nonsocial cues: an event-related potential (ERP) study. | Choi D et al. | 2017 | Journal of physiological anthropology |
| 28235397 | Unsupportive social interactions and affective states: examining associations of two oxytocin-related polymorphisms. | McInnis OA et al. | 2017 | Stress (Amsterdam, Netherlands) |
| 28341538 | The differential impact of oxytocin receptor gene in violence-exposed boys and girls. | Merrill LC et al. | 2017 | International journal of developmental neuroscience |
| 28343138 | Revisiting the impact of OXTR rs53576 on empathy: A population-based study and a meta-analysis. | Gong P et al. | 2017 | Psychoneuroendocrinology |
| 28353027 | The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene. | Tollenaar MS et al. | 2017 | European archives of psychiatry and clinical neuroscience |
| 28471218 | Change in parenting, change in student-teacher relationships, and oxytocin receptor gene (OXTR): Testing a gene-×-environment (G×E) hypothesis in two samples. | Hygen BW et al. | 2017 | Developmental psychology |
| 28499211 | Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety. | Costa B et al. | 2017 | Journal of affective disorders |
| 28530679 | Polymorphisms of the oxytocin receptor gene and overeating: the intermediary role of endophenotypic risk factors. | Davis C et al. | 2017 | Nutrition & diabetes |
| 28566712 | Developmental changes in social attention and oxytocin levels in infants and children. | Nishizato M et al. | 2017 | Scientific reports |
| 28715704 | Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study. | Sippel LM et al. | 2017 | Journal of psychiatric research |
| 28748210 | Dataset on genetic and physiological adults׳ responses to social distress. | Bonassi A et al. | 2017 | Data in brief |
| 28865941 | A field study of the association between CD38 gene and altruistic behavior: Empathic response as a mediator. | Liu J et al. | 2017 | Psychoneuroendocrinology |
| 28868757 | Depression in early adolescence: Contributions from relational aggression and variation in the oxytocin receptor gene. | Kushner SC et al. | 2018 | Aggressive behavior |
| 28912494 | Oxytocin Receptor Polymorphisms are Differentially Associated with Social Abilities across Neurodevelopmental Disorders. | Baribeau DA et al. | 2017 | Scientific reports |
| 29027364 | A functional polymorphism of the OXTR gene is associated with autistic traits in Caucasian and Asian populations. | Montag C et al. | 2017 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 29033100 | Oxytocin receptors (OXTR) and early parental care: An interaction that modulates psychiatric disorders. | Cataldo I et al. | 2018 | Research in developmental disabilities |
| 29312041 | Gaze-Following and Reaction to an Aversive Social Interaction Have Corresponding Associations with Variation in the OXTR Gene in Dogs but Not in Human Infants. | Oláh K et al. | 2017 | Frontiers in psychology |
| 29355918 | Oxytocin receptor gene polymorphisms (rs53576) and early paternal care sensitize males to distressing female vocalizations. | Truzzi A et al. | 2018 | Developmental psychobiology |
| 29623035 | Maltreatment, the Oxytocin Receptor Gene, and Conduct Problems Among Male and Female Teenagers. | Andreou D et al. | 2018 | Frontiers in human neuroscience |
| 29673618 | Association between maternal childhood maltreatment and mother-infant attachment disorganization: Moderation by maternal oxytocin receptor gene and cortisol secretion. | Ludmer JA et al. | 2018 | Hormones and behavior |
| 29674985 | Dog-Owner Attachment Is Associated With Oxytocin Receptor Gene Polymorphisms in Both Parties. A Comparative Study on Austrian and Hungarian Border Collies. | Kovács K et al. | 2018 | Frontiers in psychology |
| 29680729 | Oxytocin receptor gene (OXTR) variant rs1042778 moderates the influence of family environment on changes in perceived social support over time. | Dobewall H et al. | 2018 | Journal of affective disorders |
| 29688369 | The SNPcurator: literature mining of enriched SNP-disease associations. | Tawfik NS et al. | 2018 | Database |
| 29704085 | Associations between Oxytocin Receptor (OXTR) Genotype and Elementary School Children's Likability, Dis-likability and Friendship among Classroom Peers: A Longitudinal Study. | He J et al. | 2018 | Journal of youth and adolescence |
| 29858823 | Evidence for Association Between OXTR Gene and ASD Clinical Phenotypes. | de Oliveira Pereira Ribeiro L et al. | 2018 | Journal of molecular neuroscience |
| 29860184 | Attempted suicide and oxytocin-related gene polymorphisms. | Parris MS et al. | 2018 | Journal of affective disorders |
| 29890447 | Effect of the interaction between oxytocin receptor gene polymorphism (rs53576) and stressful life events on aggression in Chinese Han adolescents. | Shao D et al. | 2018 | Psychoneuroendocrinology |
| 29899398 | Touch-induced face conditioning is mediated by genetic variation in opioid but not oxytocin receptors. | Fu Y et al. | 2018 | Scientific reports |
| 29900533 | Relations between early maternal sensitivity and toddler self-regulation: Exploring variation by oxytocin and dopamine D2 receptor genes. | Augustine ME et al. | 2018 | Developmental psychobiology |
| 29912955 | Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects. | Vizeli P et al. | 2018 | PloS one |
| 29927293 | Oxytocin-related single-nucleotide polymorphisms, family environment, and psychopathic traits. | Verona E et al. | 2018 | Personality disorders |
| 29958244 | The late positive potential and subjective arousal ratings evoked by negative images vary as a function of oxytocin receptor genotype SNP rs53576. | Fowler JJ et al. | 2018 | Neuroreport |
| 29992684 | A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults. | Kim J et al. | 2018 | The American journal on addictions |
| 30135663 | The OXTR Single-Nucleotide Polymorphism rs53576 Moderates the Impact of Childhood Maltreatment on Empathy for Social Pain in Female Participants: Evidence for Differential Susceptibility. | Flasbeck V et al. | 2018 | Frontiers in psychiatry |
| 30202991 | Association of the oxytocin receptor gene with attitudinal trust: role of amygdala volume. | Nishina K et al. | 2018 | Social cognitive and affective neuroscience |
| 30233440 | Children's Relationship With Their Pet Dogs and OXTR Genotype Predict Child-Pet Interaction in an Experimental Setting. | Kertes DA et al. | 2018 | Frontiers in psychology |
| 30243577 | Intranasal oxytocin and OXTR genotype effects on resting state functional connectivity: A systematic review. | Seeley SH et al. | 2018 | Neuroscience and biobehavioral reviews |
| 30384146 | Interaction effects of oxytocin receptor gene polymorphism and depression on hippocampal volume. | Na KS et al. | 2018 | Psychiatry research. Neuroimaging |
| 30405505 | A Longitudinal Multilevel Study of the "Social" Genotype and Diversity of the Phenotype. | Oksman E et al. | 2018 | Frontiers in psychology |
| 30529717 | Child's oxytocin response to mother-child interaction: The contribution of child genetics and maternal behavior. | Baião R et al. | 2019 | Psychoneuroendocrinology |
| 30542304 | Oxytocin Receptor Polymorphism Decreases Midline Neural Activations to Social Stimuli in Anorexia Nervosa. | Sala M et al. | 2018 | Frontiers in psychology |
| 30572177 | Genetic and peripheral markers of the oxytocin system and parental care jointly support the cross-generational transmission of bonding across three generations. | Fujiwara T et al. | 2019 | Psychoneuroendocrinology |
| 30592969 | Implicit associations to infant cry: Genetics and early care experiences influence caregiving propensities. | Senese VP et al. | 2019 | Hormones and behavior |
| 30605805 | OXTR rs53576 polymorphism impacts interpersonal adaptability: Dispositional forgiveness as a mediator. | Zhao J et al. | 2019 | Psychoneuroendocrinology |
| 30618969 | The Oxytocin Receptor Gene (OXTR) Variant rs53576 Is Not Related to Emotional Traits or States in Young Adults. | Conner TS et al. | 2018 | Frontiers in psychology |
| 30624029 | OXTR methylation modulates exogenous oxytocin effects on human brain activity during social interaction. | Chen X et al. | 2020 | Genes, brain, and behavior |
| 30806136 | Childhood emotional neglect and oxytocin receptor variants: Association with limbic brain volumes. | Womersley JS et al. | 2020 | The world journal of biological psychiatry |
| 30818381 | Associations between spouses' oxytocin receptor gene polymorphism, attachment security, and marital satisfaction. | Monin JK et al. | 2019 | PloS one |
| 30873056 | Affective Language, Interpretation Bias and Its Molecular Genetic Variations: Exploring the Relationship Between Genetic Variations of the OXTR Gene (rs53576 and rs2268498) and the Emotional Evaluation of Words Related to the Self or the Other. | Meixner F et al. | 2019 | Frontiers in psychology |
| 30877985 | Maternal childhood adversity, OXTR genotype and cognitive load impact on perceptual and behavioral responses to infant crying. | Hiraoka D et al. | 2019 | Psychoneuroendocrinology |
| 30917144 | Caring helps: Trait empathy is related to better coping strategies and differs in the poor versus the rich. | Sun R et al. | 2019 | PloS one |
| 30918622 | The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism. | Uzefovsky F et al. | 2019 | Molecular autism |
| 30928624 | Oxytocin receptor gene (OXTR) and father support interact to predict depressive symptoms postpartum. | Bhatti P et al. | 2019 | Biological psychology |
| 31021112 | Common variants of the oxytocin receptor gene do not predict the positive mood benefits of prosocial spending. | Whillans AV et al. | 2020 | Emotion (Washington, D.C.) |
| 31025834 | Cumulative Risk of the Oxytocin Receptor Gene Interacts with Prenatal Exposure to Oxytocin Receptor Antagonist to Predict Children's Social Communication Development. | Friedlander E et al. | 2019 | Autism research |
| 31030321 | Association of OXTR rs53576 with the Developmental Trajectories of Callous-Unemotional Traits and Stressful Life Events in 3- to 9-Year-Old Community Children. | Ezpeleta L et al. | 2019 | Journal of abnormal child psychology |
| 31065789 | Maternal verbal aggression in early infancy and child's internalizing symptoms: interaction by common oxytocin polymorphisms. | Smarius LJCA et al. | 2020 | European archives of psychiatry and clinical neuroscience |
| 31070227 | Interactions between oxytocin receptor gene and intergroup relationship on empathic neural responses to others' pain. | Luo S et al. | 2019 | Social cognitive and affective neuroscience |
| 31098723 | Childhood adversity and parenting behavior: the role of oxytocin receptor gene polymorphisms. | Reichl C et al. | 2019 | Journal of neural transmission (Vienna, Austria |
| 31118457 | Interaction effect of oxytocin receptor (OXTR) rs53576 genotype and maternal postpartum depression on child behavioural problems. | Choi D et al. | 2019 | Scientific reports |
| 31133673 | Voluntary upregulation of heart rate variability through biofeedback is improved by mental contemplative training. | Bornemann B et al. | 2019 | Scientific reports |
| 31202819 | The role of oxytocinergic genes in the intergenerational transmission of parent-child relationship qualities. | Savelieva K et al. | 2019 | Hormones and behavior |
| 31233509 | Common oxytocin polymorphisms interact with maternal verbal aggression in early infancy impacting blood pressure at age 5-6: The ABCD study. | Smarius LJCA et al. | 2019 | PloS one |
| 31282733 | Associations between oxytocin receptor gene (OXTR) polymorphisms, childhood trauma, and parenting behavior. | Julian MM et al. | 2019 | Developmental psychology |
| 31291229 | Genetic Susceptibility to Posttraumatic Stress Disorder: Analyses of the Oxytocin Receptor, Retinoic Acid Receptor-Related Orphan Receptor A and Cannabinoid Receptor 1 Genes. | Kučukalić S et al. | 2019 | Psychiatria Danubina |
| 31385420 | Interaction between polymorphisms of the oxytocinergic system genes and emotion perception in inpatients with anorexia nervosa. | Kucharska K et al. | 2019 | European eating disorders review |
| 31415827 | Oxytocin modulation of self-referential processing is partly replicable and sensitive to oxytocin receptor genotype. | Zhao W et al. | 2020 | Progress in neuro-psychopharmacology & biological psychiatry |
| 31493633 | Oxytocin receptor gene polymorphisms moderate the relationship between job stress and general trust in Chinese Han university teachers. | Fang Y et al. | 2020 | Journal of affective disorders |
| 31521905 | Examining the link between emotional childhood abuse and social relationships in midlife: The moderating role of the oxytocin receptor gene. | Ebbert AM et al. | 2019 | Child abuse & neglect |
| 31587084 | A common variant in OXTR rs53576 impacts topological patterns of brain functional networks. | Wang J et al. | 2020 | European child & adolescent psychiatry |
| 31604456 | Oxytocin levels in low-risk primiparas following breast stimulation for spontaneous onset of labor: a quasi-experimental study. | Takahata K et al. | 2019 | BMC pregnancy and childbirth |
| 31718582 | Influence of oxytocin receptor single nucleotide sequence variants on contractility of human myometrium: an in vitro functional study. | Füeg F et al. | 2019 | BMC medical genetics |
| 31771350 | Association between the OXTR rs53576 genotype and latent profiles of post-traumatic stress disorder and depression symptoms in a representative sample of earthquake survivors. | Cao C et al. | 2020 | Anxiety, stress, and coping |
| 31801286 | Association Analysis of 14 Candidate Gene Polymorphism with Depression and Stress among Gestational Diabetes Mellitus. | Lee KW et al. | 2019 | Genes |
| 31908511 | The OXTR Polymorphism Stratified the Correlation of Oxytocin and Glucose Homeostasis in Non-Diabetic Subjects. | Chang HH et al. | 2019 | Diabetes, metabolic syndrome and obesity |
| 31928145 | Resting-state brain network properties mediate the association between the oxytocin receptor gene and interdependence. | Luo S et al. | 2020 | Social neuroscience |
| 32093796 | The role of schizotypal traits and the OXTR gene in theory of mind in schizophrenia: A family-based study. | Giralt-López M et al. | 2020 | European psychiatry |
| 32199286 | Interactions of OXTR rs53576 and emotional trauma on hippocampal volumes and perceived social support in adolescent girls. | Malhi GS et al. | 2020 | Psychoneuroendocrinology |
| 32227088 | Oxytocin and the stress buffering effect of social company: a genetic study in daily life. | Sicorello M et al. | 2020 | Social cognitive and affective neuroscience |
| 32291754 | Adrenocortical attunement, reactivity, and potential genetic correlates among parent-daughter dyads from low-income families. | Byrd-Craven J et al. | 2020 | Developmental psychobiology |
| 32387223 | A genetic profile of oxytocin receptor improves moral acceptability of outcome-maximizing harm in male insurance brokers. | Palumbo S et al. | 2020 | Behavioural brain research |
| 32444796 | Oxytocin receptor gene and parental bonding modulate prefrontal responses to cries: a NIRS Study. | Cataldo I et al. | 2020 | Scientific reports |
| 32457675 | After the Honeymoon: Neural and Genetic Correlates of Romantic Love in Newlywed Marriages. | Acevedo BP et al. | 2020 | Frontiers in psychology |
| 32463265 | The etiology of maternal postpartum depressive symptoms: Childhood emotional maltreatment, couple relationship satisfaction, and genes. | Cao H et al. | 2021 | Journal of family psychology |
| 32535602 | Polymorphism of the Oxytocin Receptor (OXTR) Gene Affects the Circulating Oxytocin Receptor Levels in Late-Term Pregnancy in a Turkish Population. | Akdemir N et al. | 2020 | Gynecologic and obstetric investigation |
| 32553369 | Work Stress and General Trust: The Mediating Effect of Depression and the Moderating Effect of the OXTR Gene rs53576. | Yu X et al. | 2020 | Journal of affective disorders |
| 32580785 | Oxytocin receptor gene, childhood maltreatment and borderline personality disorder features among male inmates in China. | Zhang M et al. | 2020 | BMC psychiatry |
| 32602428 | A systematic review of gene-by-intervention studies of alcohol and other substance use. | Neale ZE et al. | 2021 | Development and psychopathology |
| 32607757 | Influence of Two Single-Nucleotide Polymorphisms of the Oxytocin Receptor Gene (OXTR) on Empathy: the Mediation Role of a Primary Emotion, CARE. | Liu J et al. | 2021 | Journal of molecular neuroscience |
| 32634747 | The OXTR polymorphisms are not associated with attachment dimensions: A three-approach study. | Gong P et al. | 2020 | Psychoneuroendocrinology |
| 32693857 | An interaction between early threat exposure and the oxytocin receptor in females: Disorder-specific versus general risk for psychopathology and social-emotional mediators. | Byrd AL et al. | 2021 | Development and psychopathology |
| 32795360 | Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups. | Butovskaya M et al. | 2020 | Journal of physiological anthropology |
| 32866773 | Oxytocin Receptor Gene (OXTR) and Childhood Adversity Influence Trust. | Zheng S et al. | 2020 | Psychoneuroendocrinology |
| 32957930 | Genetic risk-factors for anxiety in healthy individuals: polymorphisms in genes important for the HPA axis. | Lindholm H et al. | 2020 | BMC medical genetics |
| 33022913 | Oxytocin Receptor Gene Polymorphisms and Early Parental Bonding Interact in Shaping Instagram Social Behavior. | Bonassi A et al. | 2020 | International journal of environmental research and public health |
| 33083876 | Strategies for Sharing Limited Resources among Children and Adolescents in Three Traditional Societies of East Africa: Sociocultural and Genetic Factors. | Butovskaya ML et al. | 2020 | Doklady biological sciences |
| 33168330 | A variation in the infant oxytocin receptor gene modulates infant hippocampal volumes in association with sex and prenatal maternal anxiety. | Acosta H et al. | 2021 | Psychiatry research. Neuroimaging |
| 33272333 | A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin. | Kou J et al. | 2022 | Psychological medicine |
| 33303340 | OXTR rs53576 Variation with Breast and Nipple Pain in Breastfeeding Women. | Lucas R et al. | 2021 | Pain management nursing |
| 33666309 | No links between genetic variation and developing theory of mind: A preregistered replication attempt of candidate gene studies. | Opitz T et al. | 2021 | Developmental science |
| 33863620 | Oxytocin receptor variant rs53576 genotype is associated with dysphoric arousal symptoms of DSM-5 posttraumatic stress disorder in Chinese earthquake survivors. | Cao CQ et al. | 2021 | Chinese journal of traumatology = Zhonghua chuang shang za zhi |
| 33866050 | Oxytocin system dysfunction in patients with treatment-resistant schizophrenia: Alterations of blood oxytocin levels and effect of a genetic variant of OXTR. | Nakata Y et al. | 2021 | Journal of psychiatric research |
| 33892530 | The influence of rs53576 polymorphism in the oxytocin receptor (OXTR) gene on empathy in healthy adults by subtype and ethnicity: a systematic review and meta-analysis. | Chander RJ et al. | 2022 | Reviews in the neurosciences |
| 33919740 | Recalled Parental Bonding Interacts with Oxytocin Receptor Gene Polymorphism in Modulating Anxiety and Avoidance in Adult Relationships. | Cataldo I et al. | 2021 | Brain sciences |
| 34023733 | Associations between oxytocin and empathy in humans: A systematic literature review. | Barchi-Ferreira AM et al. | 2021 | Psychoneuroendocrinology |
| 34091593 | Oxytocin receptor gene polymorphism and low serum oxytocin level are associated with hyperphagia and obesity in adolescents. | Çatli G et al. | 2021 | International journal of obesity (2005) |
| 34118640 | OXTR moderates adverse childhood experiences on depressive symptoms among incarcerated males. | Zhang J et al. | 2021 | Journal of psychiatric research |
| 34144447 | Gene-environment interaction: Oxytocin receptor (OXTR) polymorphisms and parenting style as potential predictors for depressive symptoms. | Keijser R et al. | 2021 | Psychiatry research |
| 34256847 | Review of eating disorders and oxytocin receptor polymorphisms. | Burmester V et al. | 2021 | Journal of eating disorders |
| 34301983 | Randomized clinical trial shows no substantial modulation of empathy-related neural activation by intranasal oxytocin in autism. | Mayer AV et al. | 2021 | Scientific reports |
| 34371296 | Genetic markers of the stress generation model: A systematic review. | Bahji A et al. | 2021 | Psychiatry research |
| 34611556 | The relation between oxytocin receptor gene polymorphisms, adult attachment and Instagram sociability: An exploratory analysis. | Carollo A et al. | 2021 | Heliyon |
| 34661982 | Oxytocin receptor polymorphism influences characterization of harm avoidance by moderating susceptibility to affectionless control parenting. | Noto K et al. | 2021 | Brain and behavior |
| 34839083 | Oxytocin receptor expression and epigenetic regulation in the anterior cingulate cortex of individuals with a history of severe childhood abuse. | Almeida D et al. | 2022 | Psychoneuroendocrinology |
| 35063684 | Oxytocin receptor genotype moderates the association between maternal prenatal stress and infant early self-regulation. | Kajanoja J et al. | 2022 | Psychoneuroendocrinology |
| 35146961 | Associations between alcohol use and peripheral, genetic, and epigenetic markers of oxytocin in a general sample of young and older adults. | Rung JM et al. | 2022 | Brain and behavior |
| 35149102 | Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: A systematic narrative review. | Kohlhoff J et al. | 2022 | Neuroscience and biobehavioral reviews |
| 35222513 | Impact of OXTR Polymorphisms on Subjective Well-Being: The Intermediary Role of Attributional Style. | Ji L et al. | 2021 | Frontiers in genetics |
| 35275212 | The OXTR rs53576 impacts moral permissibility of attempted but failed harms in populations of students and prisoners. | He L et al. | 2022 | Social cognitive and affective neuroscience |
| 35314247 | Oxytocin receptor genes moderate BDNF epigenetic methylation by childhood trauma. | Lee HS et al. | 2022 | Journal of affective disorders |
| 35462200 | Oxytocin modulates sensitivity to acculturation and discrimination stress in pregnancy. | Rodriguez ACI et al. | 2022 | Psychoneuroendocrinology |
| 35564961 | The Interaction Effect of Parental Rejection and Oxytocin Receptor Gene Polymorphism on Depression: A Cross-Cultural Study in Non-Clinical Samples. | Senese VP et al. | 2022 | International journal of environmental research and public health |
| 35756198 | Gene-Environment Interactions in Face Categorization: Oxytocin Receptor Genotype x Childcare Experience Shortens Reaction Time. | Neoh MJY et al. | 2022 | Frontiers in psychology |
| 35905808 | Physical activity associates empathy in Japanese young adults with specific gene variations of oxytocin receptor and vasopressin V1B receptor. | Shima T et al. | 2022 | Physiology & behavior |
| 35995218 | Associations of air PM(2.5) level with gut microbiota in Chinese Han preschoolers and effect modification by oxytocin receptor gene polymorphism. | Sun Y et al. | 2022 | Environmental research |
| 36098825 | Joint Roles of Oxytocin- and Dopamine-Related Genes and Childhood Parenting Experience in Maternal Supportive Social Network. | Koyama Y et al. | 2024 | Child psychiatry and human development |
Help
The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.
Genome context:
Select flank length:
Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.