Name: rs237889
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs237889

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr3:8760797 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: T>C
Variation Type: SNV Single Nucleotide Variation
Frequency: T=0.279791 (74058/264690, TOPMED)
T=0.357773 (72537/202746, ALFA)
T=0.288318 (40376/140040, GnomAD) (+ 21 more)
T=0.45732 (12923/28258, 14KJPN)
T=0.45758 (7669/16760, 8.3KJPN)
T=0.2906 (1861/6404, 1000G_30x)
T=0.2997 (1501/5008, 1000G)
T=0.3583 (1605/4480, Estonian)
T=0.3861 (1488/3854, ALSPAC)
T=0.3797 (1408/3708, TWINSUK)
T=0.4321 (1266/2930, KOREAN)
T=0.3129 (652/2084, HGDP_Stanford)
T=0.2868 (542/1890, HapMap)
T=0.4389 (804/1832, Korea1K)
T=0.4177 (472/1130, Daghestan)
T=0.399 (398/998, GoNL)
T=0.441 (348/790, PRJEB37584)
T=0.370 (222/600, NorthernSweden)
T=0.209 (103/492, SGDP_PRJ)
T=0.356 (77/216, Qatari)
T=0.322 (69/214, Vietnamese)
T=0.412 (42/102, Ancient Sardinia)
T=0.25 (12/48, Siberian)
T=0.33 (13/40, GENOME_DK)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: OXTR : Intron Variant
Publications: 15 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	202746	T=0.357773	C=0.642227
European	Sub	172816	T=0.374161	C=0.625839
African	Sub	9728	T=0.1372	C=0.8628
African Others	Sub	348	T=0.078	C=0.922
African American	Sub	9380	T=0.1394	C=0.8606
Asian	Sub	704	T=0.423	C=0.577
East Asian	Sub	558	T=0.423	C=0.577
Other Asian	Sub	146	T=0.425	C=0.575
Latin American 1	Sub	844	T=0.289	C=0.711
Latin American 2	Sub	6900	T=0.2242	C=0.7758
South Asian	Sub	5042	T=0.4284	C=0.5716
Other	Sub	6712	T=0.3415	C=0.6585

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	T=0.279791	C=0.720209
Allele Frequency Aggregator	Total	Global	202746	T=0.357773	C=0.642227
Allele Frequency Aggregator	European	Sub	172816	T=0.374161	C=0.625839
Allele Frequency Aggregator	African	Sub	9728	T=0.1372	C=0.8628
Allele Frequency Aggregator	Latin American 2	Sub	6900	T=0.2242	C=0.7758
Allele Frequency Aggregator	Other	Sub	6712	T=0.3415	C=0.6585
Allele Frequency Aggregator	South Asian	Sub	5042	T=0.4284	C=0.5716
Allele Frequency Aggregator	Latin American 1	Sub	844	T=0.289	C=0.711
Allele Frequency Aggregator	Asian	Sub	704	T=0.423	C=0.577
gnomAD - Genomes	Global	Study-wide	140040	T=0.288318	C=0.711682
gnomAD - Genomes	European	Sub	75828	T=0.36815	C=0.63185
gnomAD - Genomes	African	Sub	41968	T=0.13618	C=0.86382
gnomAD - Genomes	American	Sub	13650	T=0.25553	C=0.74447
gnomAD - Genomes	Ashkenazi Jewish	Sub	3320	T=0.3810	C=0.6190
gnomAD - Genomes	East Asian	Sub	3124	T=0.4267	C=0.5733
gnomAD - Genomes	Other	Sub	2150	T=0.3065	C=0.6935
14KJPN	JAPANESE	Study-wide	28258	T=0.45732	C=0.54268
8.3KJPN	JAPANESE	Study-wide	16760	T=0.45758	C=0.54242
1000Genomes_30x	Global	Study-wide	6404	T=0.2906	C=0.7094
1000Genomes_30x	African	Sub	1786	T=0.0918	C=0.9082
1000Genomes_30x	Europe	Sub	1266	T=0.3989	C=0.6011
1000Genomes_30x	South Asian	Sub	1202	T=0.4334	C=0.5666
1000Genomes_30x	East Asian	Sub	1170	T=0.4051	C=0.5949
1000Genomes_30x	American	Sub	980	T=0.201	C=0.799
1000Genomes	Global	Study-wide	5008	T=0.2997	C=0.7003
1000Genomes	African	Sub	1322	T=0.0923	C=0.9077
1000Genomes	East Asian	Sub	1008	T=0.4117	C=0.5883
1000Genomes	Europe	Sub	1006	T=0.4006	C=0.5994
1000Genomes	South Asian	Sub	978	T=0.434	C=0.566
1000Genomes	American	Sub	694	T=0.197	C=0.803
Genetic variation in the Estonian population	Estonian	Study-wide	4480	T=0.3583	C=0.6417
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.3861	C=0.6139
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.3797	C=0.6203
KOREAN population from KRGDB	KOREAN	Study-wide	2930	T=0.4321	C=0.5679
HGDP-CEPH-db Supplement 1	Global	Study-wide	2084	T=0.3129	C=0.6871
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	T=0.381	C=0.619
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	T=0.401	C=0.599
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	T=0.377	C=0.623
HGDP-CEPH-db Supplement 1	Europe	Sub	320	T=0.353	C=0.647
HGDP-CEPH-db Supplement 1	Africa	Sub	242	T=0.074	C=0.926
HGDP-CEPH-db Supplement 1	America	Sub	216	T=0.093	C=0.907
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	T=0.33	C=0.67
HapMap	Global	Study-wide	1890	T=0.2868	C=0.7132
HapMap	American	Sub	770	T=0.334	C=0.666
HapMap	African	Sub	690	T=0.146	C=0.854
HapMap	Asian	Sub	254	T=0.453	C=0.547
HapMap	Europe	Sub	176	T=0.392	C=0.608
Korean Genome Project	KOREAN	Study-wide	1832	T=0.4389	C=0.5611
Genome-wide autozygosity in Daghestan	Global	Study-wide	1130	T=0.4177	C=0.5823
Genome-wide autozygosity in Daghestan	Daghestan	Sub	626	T=0.431	C=0.569
Genome-wide autozygosity in Daghestan	Near_East	Sub	142	T=0.430	C=0.570
Genome-wide autozygosity in Daghestan	Central Asia	Sub	122	T=0.385	C=0.615
Genome-wide autozygosity in Daghestan	Europe	Sub	108	T=0.389	C=0.611
Genome-wide autozygosity in Daghestan	South Asian	Sub	96	T=0.36	C=0.64
Genome-wide autozygosity in Daghestan	Caucasus	Sub	36	T=0.47	C=0.53
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	T=0.399	C=0.601
CNV burdens in cranial meningiomas	Global	Study-wide	790	T=0.441	C=0.559
CNV burdens in cranial meningiomas	CRM	Sub	790	T=0.441	C=0.559
Northern Sweden	ACPOP	Study-wide	600	T=0.370	C=0.630
SGDP_PRJ	Global	Study-wide	492	T=0.209	C=0.791
Qatari	Global	Study-wide	216	T=0.356	C=0.644
A Vietnamese Genetic Variation Database	Global	Study-wide	214	T=0.322	C=0.678
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	102	T=0.412	C=0.588
Siberian	Global	Study-wide	48	T=0.25	C=0.75
The Danish reference pan genome	Danish	Study-wide	40	T=0.33	C=0.68

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 3	NC_000003.12:g.8760797T>C
GRCh37.p13 chr 3	NC_000003.11:g.8802483T>C
CAV3 RefSeqGene (LRG_329)	NG_008797.2:g.31988T>C

Gene: OXTR, oxytocin receptor (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
OXTR transcript variant 1	NM_000916.4:c.922+6469A>G	N/A	Intron Variant
OXTR transcript variant 2	NM_001354653.2:c.922+6469… NM_001354653.2:c.922+6469A>G	N/A	Intron Variant
OXTR transcript variant 3	NM_001354654.2:c.922+6469… NM_001354654.2:c.922+6469A>G	N/A	Intron Variant
OXTR transcript variant 4	NM_001354655.2:c.922+6469… NM_001354655.2:c.922+6469A>G	N/A	Intron Variant
OXTR transcript variant 5	NM_001354656.3:c.922+6469… NM_001354656.3:c.922+6469A>G	N/A	Intron Variant
OXTR transcript variant X1	XR_007095681.1:n.	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	T=	C
GRCh38.p14 chr 3	NC_000003.12:g.8760797=	NC_000003.12:g.8760797T>C
GRCh37.p13 chr 3	NC_000003.11:g.8802483=	NC_000003.11:g.8802483T>C
CAV3 RefSeqGene (LRG_329)	NG_008797.2:g.31988=	NG_008797.2:g.31988T>C
OXTR transcript variant 1	NM_000916.3:c.922+6469=	NM_000916.3:c.922+6469A>G
OXTR transcript variant 1	NM_000916.4:c.922+6469=	NM_000916.4:c.922+6469A>G
OXTR transcript variant 2	NM_001354653.2:c.922+6469=	NM_001354653.2:c.922+6469A>G
OXTR transcript variant 3	NM_001354654.2:c.922+6469=	NM_001354654.2:c.922+6469A>G
OXTR transcript variant 4	NM_001354655.2:c.922+6469=	NM_001354655.2:c.922+6469A>G
OXTR transcript variant 5	NM_001354656.3:c.922+6469=	NM_001354656.3:c.922+6469A>G

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

134 SubSNP, 24 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	KWOK	ss306655	Jul 12, 2000 (79)
2	KWOK	ss439095	Jul 12, 2000 (85)
3	SC_JCM	ss557637	Jul 16, 2000 (80)
4	KWOK	ss1014569	Oct 04, 2000 (86)
5	KWOK	ss1055344	Oct 04, 2000 (86)
6	KWOK	ss1652911	Oct 18, 2000 (87)
7	BCM_SSAHASNP	ss10078351	Jul 11, 2003 (116)
8	BCM_SSAHASNP	ss14176212	Dec 05, 2003 (119)
9	ABI	ss44467795	Mar 14, 2006 (126)
10	ILLUMINA	ss66837030	Nov 30, 2006 (127)
11	ILLUMINA	ss67250394	Nov 30, 2006 (127)
12	ILLUMINA	ss67648023	Nov 30, 2006 (127)
13	ILLUMINA	ss70728730	May 24, 2008 (130)
14	ILLUMINA	ss71297935	May 17, 2007 (127)
15	ILLUMINA	ss75911310	Dec 06, 2007 (129)
16	ILLUMINA	ss79132424	Dec 15, 2007 (130)
17	KRIBB_YJKIM	ss83397835	Dec 15, 2007 (130)
18	HGSV	ss85244424	Dec 15, 2007 (130)
19	HGSV	ss86195447	Dec 15, 2007 (130)
20	BCMHGSC_JDW	ss91992548	Mar 24, 2008 (129)
21	HUMANGENOME_JCVI	ss95983127	Feb 05, 2009 (130)
22	BGI	ss106240471	Feb 05, 2009 (130)
23	1000GENOMES	ss111225247	Jan 25, 2009 (130)
24	ILLUMINA-UK	ss116967898	Feb 14, 2009 (130)
25	ILLUMINA	ss122019970	Dec 01, 2009 (131)
26	ENSEMBL	ss133252764	Dec 01, 2009 (131)
27	ILLUMINA	ss153908096	Dec 01, 2009 (131)
28	GMI	ss155083168	Dec 01, 2009 (131)
29	ILLUMINA	ss159385957	Dec 01, 2009 (131)
30	ILLUMINA	ss160541693	Dec 01, 2009 (131)
31	COMPLETE_GENOMICS	ss161915041	Jul 04, 2010 (132)
32	COMPLETE_GENOMICS	ss163085937	Jul 04, 2010 (132)
33	COMPLETE_GENOMICS	ss166129332	Jul 04, 2010 (132)
34	ILLUMINA	ss171228792	Jul 04, 2010 (132)
35	ILLUMINA	ss173316551	Jul 04, 2010 (132)
36	BUSHMAN	ss202109369	Jul 04, 2010 (132)
37	BCM-HGSC-SUB	ss206177966	Jul 04, 2010 (132)
38	1000GENOMES	ss211134083	Jul 14, 2010 (132)
39	1000GENOMES	ss219970752	Jul 14, 2010 (132)
40	1000GENOMES	ss231700297	Jul 14, 2010 (132)
41	1000GENOMES	ss239135787	Jul 15, 2010 (132)
42	BL	ss252921830	May 09, 2011 (134)
43	GMI	ss277006564	May 04, 2012 (137)
44	GMI	ss284591701	Apr 25, 2013 (138)
45	PJP	ss292858687	May 09, 2011 (134)
46	ILLUMINA	ss480551111	May 04, 2012 (137)
47	ILLUMINA	ss480565160	May 04, 2012 (137)
48	ILLUMINA	ss481381202	Sep 08, 2015 (146)
49	ILLUMINA	ss485071263	May 04, 2012 (137)
50	ILLUMINA	ss537084146	Sep 08, 2015 (146)
51	TISHKOFF	ss556413324	Apr 25, 2013 (138)
52	SSMP	ss650078310	Apr 25, 2013 (138)
53	ILLUMINA	ss778867312	Sep 08, 2015 (146)
54	ILLUMINA	ss782981903	Sep 08, 2015 (146)
55	ILLUMINA	ss783942912	Sep 08, 2015 (146)
56	ILLUMINA	ss825462942	Apr 01, 2015 (144)
57	ILLUMINA	ss832238453	Sep 08, 2015 (146)
58	ILLUMINA	ss832897723	Jul 13, 2019 (153)
59	ILLUMINA	ss834328172	Sep 08, 2015 (146)
60	EVA-GONL	ss978252142	Aug 21, 2014 (142)
61	JMKIDD_LAB	ss1070160706	Aug 21, 2014 (142)
62	1000GENOMES	ss1302724932	Aug 21, 2014 (142)
63	HAMMER_LAB	ss1397329052	Sep 08, 2015 (146)
64	DDI	ss1429324844	Apr 01, 2015 (144)
65	EVA_GENOME_DK	ss1579837607	Apr 01, 2015 (144)
66	EVA_DECODE	ss1587712249	Apr 01, 2015 (144)
67	EVA_UK10K_ALSPAC	ss1606373011	Apr 01, 2015 (144)
68	EVA_UK10K_TWINSUK	ss1649367044	Apr 01, 2015 (144)
69	EVA_SVP	ss1712552154	Apr 01, 2015 (144)
70	ILLUMINA	ss1752486627	Sep 08, 2015 (146)
71	HAMMER_LAB	ss1798826749	Sep 08, 2015 (146)
72	WEILL_CORNELL_DGM	ss1921503700	Feb 12, 2016 (147)
73	GENOMED	ss1969318786	Jul 19, 2016 (147)
74	JJLAB	ss2021304659	Sep 14, 2016 (149)
75	USC_VALOUEV	ss2149371885	Dec 20, 2016 (150)
76	HUMAN_LONGEVITY	ss2248922594	Dec 20, 2016 (150)
77	SYSTEMSBIOZJU	ss2625152845	Nov 08, 2017 (151)
78	ILLUMINA	ss2633908603	Nov 08, 2017 (151)
79	GRF	ss2704730722	Nov 08, 2017 (151)
80	GNOMAD	ss2789316189	Nov 08, 2017 (151)
81	AFFY	ss2985865366	Nov 08, 2017 (151)
82	SWEGEN	ss2991798852	Nov 08, 2017 (151)
83	BIOINF_KMB_FNS_UNIBA	ss3024415271	Nov 08, 2017 (151)
84	CSHL	ss3344875978	Nov 08, 2017 (151)
85	ILLUMINA	ss3628585002	Oct 11, 2018 (152)
86	ILLUMINA	ss3631857433	Oct 11, 2018 (152)
87	ILLUMINA	ss3633281146	Oct 11, 2018 (152)
88	ILLUMINA	ss3633997567	Oct 11, 2018 (152)
89	ILLUMINA	ss3634878997	Oct 11, 2018 (152)
90	ILLUMINA	ss3635681785	Oct 11, 2018 (152)
91	ILLUMINA	ss3636575239	Oct 11, 2018 (152)
92	ILLUMINA	ss3637434082	Oct 11, 2018 (152)
93	ILLUMINA	ss3638395765	Oct 11, 2018 (152)
94	ILLUMINA	ss3639201676	Oct 11, 2018 (152)
95	ILLUMINA	ss3639618288	Oct 11, 2018 (152)
96	ILLUMINA	ss3640586300	Oct 11, 2018 (152)
97	ILLUMINA	ss3643354230	Oct 11, 2018 (152)
98	URBANLAB	ss3647336467	Oct 11, 2018 (152)
99	EGCUT_WGS	ss3659698778	Jul 13, 2019 (153)
100	EVA_DECODE	ss3708598180	Jul 13, 2019 (153)
101	ACPOP	ss3729615725	Jul 13, 2019 (153)
102	ILLUMINA	ss3745178808	Jul 13, 2019 (153)
103	EVA	ss3759636171	Jul 13, 2019 (153)
104	ILLUMINA	ss3772674613	Jul 13, 2019 (153)
105	PACBIO	ss3784229970	Jul 13, 2019 (153)
106	PACBIO	ss3789759443	Jul 13, 2019 (153)
107	PACBIO	ss3794633186	Jul 13, 2019 (153)
108	KHV_HUMAN_GENOMES	ss3802787938	Jul 13, 2019 (153)
109	EVA	ss3827651684	Apr 25, 2020 (154)
110	EVA	ss3837247594	Apr 25, 2020 (154)
111	EVA	ss3842671347	Apr 25, 2020 (154)
112	HGDP	ss3847697126	Apr 25, 2020 (154)
113	SGDP_PRJ	ss3855186505	Apr 25, 2020 (154)
114	KRGDB	ss3900953538	Apr 25, 2020 (154)
115	KOGIC	ss3950623457	Apr 25, 2020 (154)
116	EVA	ss3984502598	Apr 26, 2021 (155)
117	EVA	ss3984971603	Apr 26, 2021 (155)
118	EVA	ss4017063688	Apr 26, 2021 (155)
119	TOPMED	ss4553568166	Apr 26, 2021 (155)
120	TOMMO_GENOMICS	ss5157709886	Apr 26, 2021 (155)
121	1000G_HIGH_COVERAGE	ss5252980950	Oct 13, 2022 (156)
122	EVA	ss5314831929	Oct 13, 2022 (156)
123	EVA	ss5337766707	Oct 13, 2022 (156)
124	HUGCELL_USP	ss5452489423	Oct 13, 2022 (156)
125	1000G_HIGH_COVERAGE	ss5530780672	Oct 13, 2022 (156)
126	SANFORD_IMAGENETICS	ss5631504580	Oct 13, 2022 (156)
127	TOMMO_GENOMICS	ss5688951368	Oct 13, 2022 (156)
128	EVA	ss5799568963	Oct 13, 2022 (156)
129	YY_MCH	ss5803464041	Oct 13, 2022 (156)
130	EVA	ss5825319955	Oct 13, 2022 (156)
131	EVA	ss5853482336	Oct 13, 2022 (156)
132	EVA	ss5867551607	Oct 13, 2022 (156)
133	EVA	ss5959762298	Oct 13, 2022 (156)
134	EVA	ss5980129089	Oct 13, 2022 (156)
135	1000Genomes	NC_000003.11 - 8802483	Oct 11, 2018 (152)
136	1000Genomes_30x	NC_000003.12 - 8760797	Oct 13, 2022 (156)
137	The Avon Longitudinal Study of Parents and Children	NC_000003.11 - 8802483	Oct 11, 2018 (152)
138	Genome-wide autozygosity in Daghestan	NC_000003.10 - 8777483	Apr 25, 2020 (154)
139	Genetic variation in the Estonian population	NC_000003.11 - 8802483	Oct 11, 2018 (152)
140	The Danish reference pan genome	NC_000003.11 - 8802483	Apr 25, 2020 (154)
141	gnomAD - Genomes	NC_000003.12 - 8760797	Apr 26, 2021 (155)
142	Genome of the Netherlands Release 5	NC_000003.11 - 8802483	Apr 25, 2020 (154)
143	HGDP-CEPH-db Supplement 1	NC_000003.10 - 8777483	Apr 25, 2020 (154)
144	HapMap	NC_000003.12 - 8760797	Apr 25, 2020 (154)
145	KOREAN population from KRGDB	NC_000003.11 - 8802483	Apr 25, 2020 (154)
146	Korean Genome Project	NC_000003.12 - 8760797	Apr 25, 2020 (154)
147	Northern Sweden	NC_000003.11 - 8802483	Jul 13, 2019 (153)
148	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000003.11 - 8802483	Apr 26, 2021 (155)
149	CNV burdens in cranial meningiomas	NC_000003.11 - 8802483	Apr 26, 2021 (155)
150	Qatari	NC_000003.11 - 8802483	Apr 25, 2020 (154)
151	SGDP_PRJ	NC_000003.11 - 8802483	Apr 25, 2020 (154)
152	Siberian	NC_000003.11 - 8802483	Apr 25, 2020 (154)
153	8.3KJPN	NC_000003.11 - 8802483	Apr 26, 2021 (155)
154	14KJPN	NC_000003.12 - 8760797	Oct 13, 2022 (156)
155	TopMed	NC_000003.12 - 8760797	Apr 26, 2021 (155)
156	UK 10K study - Twins	NC_000003.11 - 8802483	Oct 11, 2018 (152)
157	A Vietnamese Genetic Variation Database	NC_000003.11 - 8802483	Jul 13, 2019 (153)
158	ALFA	NC_000003.12 - 8760797	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs345113	Sep 19, 2000 (85)
rs58435790	May 24, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss85244424, ss86195447, ss3639201676, ss3639618288	NC_000003.9:8777482:T:C	NC_000003.12:8760796:T:C	(self)
305165, 375018, ss91992548, ss111225247, ss116967898, ss161915041, ss163085937, ss166129332, ss202109369, ss206177966, ss211134083, ss252921830, ss277006564, ss284591701, ss292858687, ss480551111, ss825462942, ss1397329052, ss1587712249, ss1712552154, ss3643354230, ss3847697126	NC_000003.10:8777482:T:C	NC_000003.12:8760796:T:C	(self)
13867116, 7686098, 5437026, 6002546, 3375523, 8130932, 2900590, 197530, 51940, 3545630, 7203485, 1888239, 15679193, 7686098, 1673744, ss219970752, ss231700297, ss239135787, ss480565160, ss481381202, ss485071263, ss537084146, ss556413324, ss650078310, ss778867312, ss782981903, ss783942912, ss832238453, ss832897723, ss834328172, ss978252142, ss1070160706, ss1302724932, ss1429324844, ss1579837607, ss1606373011, ss1649367044, ss1752486627, ss1798826749, ss1921503700, ss1969318786, ss2021304659, ss2149371885, ss2625152845, ss2633908603, ss2704730722, ss2789316189, ss2985865366, ss2991798852, ss3344875978, ss3628585002, ss3631857433, ss3633281146, ss3633997567, ss3634878997, ss3635681785, ss3636575239, ss3637434082, ss3638395765, ss3640586300, ss3659698778, ss3729615725, ss3745178808, ss3759636171, ss3772674613, ss3784229970, ss3789759443, ss3794633186, ss3827651684, ss3837247594, ss3855186505, ss3900953538, ss3984502598, ss3984971603, ss4017063688, ss5157709886, ss5314831929, ss5337766707, ss5631504580, ss5799568963, ss5825319955, ss5959762298, ss5980129089	NC_000003.11:8802482:T:C	NC_000003.12:8760796:T:C	(self)
18306607, 98487470, 2299057, 7001458, 22788472, 390945721, 1666476366, ss2248922594, ss3024415271, ss3647336467, ss3708598180, ss3802787938, ss3842671347, ss3950623457, ss4553568166, ss5252980950, ss5452489423, ss5530780672, ss5688951368, ss5803464041, ss5853482336, ss5867551607	NC_000003.12:8760796:T:C	NC_000003.12:8760796:T:C	(self)
ss10078351	NT_005927.15:8731328:T:C	NC_000003.12:8760796:T:C	(self)
ss14176212	NT_022517.16:8742482:T:C	NC_000003.12:8760796:T:C	(self)
ss306655, ss439095, ss557637, ss1014569, ss1055344, ss1652911, ss44467795, ss66837030, ss67250394, ss67648023, ss70728730, ss71297935, ss75911310, ss79132424, ss83397835, ss95983127, ss106240471, ss122019970, ss133252764, ss153908096, ss155083168, ss159385957, ss160541693, ss171228792, ss173316551	NT_022517.18:8742482:T:C	NC_000003.12:8760796:T:C	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

15 citations for rs237889

PMID	Title	Author	Year	Journal
17668382	Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.	Salonen JT et al.	2007	American journal of human genetics
17893705	Association between the oxytocin receptor (OXTR) gene and autism: relationship to Vineland Adaptive Behavior Scales and cognition.	Lerer E et al.	2008	Molecular psychiatry
19461999	The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task.	Israel S et al.	2009	PloS one
21484202	Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder.	Campbell DB et al.	2011	Journal of neurodevelopmental disorders
21934640	Test of association between 10 single nucleotide polymorphisms in the oxytocin receptor gene and conduct disorder.	Sakai JT et al.	2012	Psychiatric genetics
23092589	Colorado Twin Registry: an update.	Rhea SA et al.	2013	Twin research and human genetics
24059750	Polymorphisms in the oxytocin receptor gene are associated with the development of psychopathy.	Dadds MR et al.	2014	Development and psychopathology
26788924	Meta-analysis and association of two common polymorphisms of the human oxytocin receptor gene in autism spectrum disorder.	Kranz TM et al.	2016	Autism research
27242401	Variants in Adjacent Oxytocin/Vasopressin Gene Region and Associations with ASD Diagnosis and Other Autism Related Endophenotypes.	Francis SM et al.	2016	Frontiers in neuroscience
27458336	Genetic Syndromes, Maternal Diseases and Antenatal Factors Associated with Autism Spectrum Disorders (ASD).	Ornoy A et al.	2016	Frontiers in neuroscience
27497314	Variation in the oxytocin receptor gene (OXTR) is associated with differences in moral judgment.	Bernhard RM et al.	2016	Social cognitive and affective neuroscience
27920663	ASD and Genetic Associations with Receptors for Oxytocin and Vasopressin-AVPR1A, AVPR1B, and OXTR.	Francis SM et al.	2016	Frontiers in neuroscience
30093869	Biological Predictors of Clozapine Response: A Systematic Review.	Samanaite R et al.	2018	Frontiers in psychiatry
34144447	Gene-environment interaction: Oxytocin receptor (OXTR) polymorphisms and parenting style as potential predictors for depressive symptoms.	Keijser R et al.	2021	Psychiatry research
35385511	Moral judgment and hormones: A systematic literature review.	Freitas CCMC et al.	2022	PloS one

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs237889