3-Methoxy-4-hydroxyphenylglycol (MHPG, MOPEG) is a metabolite of norepinephrine degradation. In the brain, it is the principal norepinephrine metabolite. It is released into the blood and cerebrospinal fluid, and a blood sample of it may therefore be an indication of recent sympathetic nervous system activity.
Low levels of MHPG in the blood and cerebrospinal fluid are associated with anorexia nervosa and pathological gambling, indicating that norepinephrine may play a role in these behaviors. |
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InChI=1S/C24H34O9/c1- 12(2) 7- 18(27) 32- 16- 9- 23(10- 29- 14(4) 25) 17(8- 13(16) 3) 33- 21- 19(28) 20(31- 15(5) 26) 22(23,6) 24(21) 11- 30- 24/h8,12,16- 17,19- 21,28H,7,9- 11H2,1- 6H3/t16- ,17+,19+,20+,21+,22+,23+,24- /m0/s1 |
BXFOFFBJRFZBQZ-QYWOHJEZSA-N |
[H] [C@@] 12O[C@] 3([H] ) C=C(C) [C@H] (C[C@] 3(COC(C) =O) [C@@] (C) ([C@H] (OC(C) =O) [C@H] 1O) [C@] 21CO1) OC(=O) CC(C) C |
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Fusarium sp.rotrichioides
(NCBI:txid5514)
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of strain
NRRL3299
See:
PubMed
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Fusarium graminearum
(NCBI:txid5518)
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of strain
Z-3639
See:
PubMed
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environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
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DNA synthesis inhibitor
Any substance that inhibits the synthesis of DNA.
fungal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
mycotoxin
Poisonous substance produced by fungi.
(via trichothecene )
cardiotoxic agent
A role played by a chemical compound exhibiting itself through the ability to induce damage to the heart and cardiomyocytes.
neurotoxin
A poison that interferes with the functions of the nervous system.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
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View more via ChEBI Ontology
4β,15-bis(acetyloxy)-3α-hydroxy-12,13-epoxytrichothec-9-en-8α-yl 3-methylbutanoate
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(3α,4β,8α)- 12,13- epoxy- 4,15- diacetate 8- (3- methylbutanoate)trichothec- 9- ene- 3,4,8,15- tetrol
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ChEBI
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3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-δ-9-trichothecene
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ChemIDplus
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4β,15-diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
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ChEBI
|
fusariotoxin T 2
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ChemIDplus
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fusariotoxin T-2
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ChEBI
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fusariotoxine T2
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ChemIDplus
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insariotoxin
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ChemIDplus
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isaritoxin
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ChemIDplus
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mycotoxin T-2
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ChemIDplus
|
T-2 mycotoxin
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ChemIDplus
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T2 toxin
|
ChemIDplus
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T2-trichothecene
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ChemIDplus
|
toxin T2
|
ChemIDplus
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21259-20-1
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CAS Registry Number
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ChemIDplus
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21259-20-1
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CAS Registry Number
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NIST Chemistry WebBook
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3575695
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Reaxys Registry Number
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Reaxys
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16604118
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PubMed citation
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Europe PMC
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22069741
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PubMed citation
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Europe PMC
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28430618
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PubMed citation
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Europe PMC
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29433086
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Europe PMC
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31570981
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Europe PMC
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31653066
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31886226
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Europe PMC
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31895560
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PubMed citation
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Europe PMC
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31981685
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Europe PMC
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32214355
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PubMed citation
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Europe PMC
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32229328
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Europe PMC
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32451776
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Europe PMC
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32545742
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Europe PMC
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Europe PMC
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Europe PMC
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Europe PMC
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Europe PMC
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Europe PMC
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32798696
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Europe PMC
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Europe PMC
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PubMed citation
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Europe PMC
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32839860
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Europe PMC
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Europe PMC
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32910237
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Europe PMC
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32928346
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Europe PMC
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32990831
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PubMed citation
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Europe PMC
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IND606948730
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Agricola citation
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