CHEBI:81565 - resolvin D2

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ChEBI Name resolvin D2
ChEBI ID CHEBI:81565
Definition A member of the class of resolvins that is (4Z,8E,10Z,12E,14E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 7, 16 and 17 (the 7S,16R,17S-stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB5235360, eMolecules:524685
Download Molfile XML SDF
Formula C22H32O5
Net Charge 0
Average Mass 376.487
Monoisotopic Mass 376.22497
InChI InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20+,21-/m1/s1
InChIKey IKFAUGXNBOBQDM-XFMPMKITSA-N
SMILES C(C/C=C\C[C@@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](C/C=C\CC)O)O)O)C(O)=O
Metabolite of Species Details
Rattus norvegicus (NCBI:txid10116) See: PubMed
Homo Sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
estrogen receptor agonist
An agonist at the estrogen receptor.
anti-obesity agent
Any substance which is used to reduce or control weight.
rat metabolite
Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus).
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing resolvin D2 (CHEBI:81565) has role anti-inflammatory agent (CHEBI:67079)
resolvin D2 (CHEBI:81565) has role anti-obesity agent (CHEBI:74518)
resolvin D2 (CHEBI:81565) has role estrogen receptor agonist (CHEBI:63951)
resolvin D2 (CHEBI:81565) has role human xenobiotic metabolite (CHEBI:76967)
resolvin D2 (CHEBI:81565) has role rat metabolite (CHEBI:86264)
resolvin D2 (CHEBI:81565) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
resolvin D2 (CHEBI:81565) is a resolvin (CHEBI:132120)
resolvin D2 (CHEBI:81565) is a secondary allylic alcohol (CHEBI:134396)
resolvin D2 (CHEBI:81565) is a triol (CHEBI:27136)
resolvin D2 (CHEBI:81565) is conjugate acid of resolvin D2(1−) (CHEBI:133367)
Incoming resolvin D2(1−) (CHEBI:133367) is conjugate base of resolvin D2 (CHEBI:81565)
IUPAC Name
(4Z,7R,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid
Synonyms Sources
7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid LIPID MAPS
RVD2 HMDB
Manual Xrefs Databases
C18179 KEGG COMPOUND
CPD66-65 MetaCyc
HMDB0002294 HMDB
LMFA04000007 LIPID MAPS
View more database links
Registry Numbers Types Sources
82864-77-5 CAS Registry Number HMDB
9876619 Reaxys Registry Number Reaxys
Citations Types Sources
19865173 PubMed citation Europe PMC
21724996 PubMed citation Europe PMC
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27531933 PubMed citation Europe PMC
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27619672 PubMed citation Europe PMC
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28063958 PubMed citation Europe PMC
28086928 PubMed citation Europe PMC
Last Modified
05 March 2018