CHEBI:81564 - resolvin D1

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ChEBI Name resolvin D1
ChEBI ID CHEBI:81564
Definition A resolvin that is docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid which is substituted by hydroxy groups at the 7, 8, and 17 positions (the 7S,8R,17S-stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB3326778, eMolecules:518114, eMolecules:1844537, ZINC000000388081
Download Molfile XML SDF
Formula C22H32O5
Net Charge 0
Average Mass 376.487
Monoisotopic Mass 376.22497
InChI InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20+,21-/m0/s1
InChIKey OIWTWACQMDFHJG-CCFUIAGSSA-N
SMILES C(\CCC(O)=O)=C\C[C@@H]([C@@H](\C=C\C=C\C=C/C=C/[C@H](C/C=C\CC)O)O)O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) Found in blood (UBERON:0000178). See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing resolvin D1 (CHEBI:81564) has role anti-inflammatory agent (CHEBI:67079)
resolvin D1 (CHEBI:81564) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
resolvin D1 (CHEBI:81564) is a resolvin (CHEBI:132120)
resolvin D1 (CHEBI:81564) is a triol (CHEBI:27136)
resolvin D1 (CHEBI:81564) is conjugate acid of resolvin D1(1−) (CHEBI:132079)
Incoming resolvin D1(1−) (CHEBI:132079) is conjugate base of resolvin D1 (CHEBI:81564)
IUPAC Name
(4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
Synonyms Sources
7S,8,17S-Trihydroxy-docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoate HMDB
7S,8,17S-Trihydroxy-docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid HMDB
7S,8R,17S-Trihydroxydocosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid KEGG COMPOUND
RvD1 HMDB
Manual Xrefs Databases
C18178 KEGG COMPOUND
CPD66-64 MetaCyc
HMDB0003733 HMDB
LMFA04000006 LIPID MAPS
View more database links
Registry Number Type Source
20871109 Reaxys Registry Number Reaxys
Citations Types Sources
17090225 PubMed citation Europe PMC
17244615 PubMed citation Europe PMC
21359215 PubMed citation Europe PMC
26462421 PubMed citation Europe PMC
26531230 PubMed citation Europe PMC
26597784 PubMed citation Europe PMC
26630551 PubMed citation Europe PMC
26702138 PubMed citation Europe PMC
26808633 PubMed citation Europe PMC
26843331 PubMed citation Europe PMC
26878867 PubMed citation Europe PMC
26969756 PubMed citation Europe PMC
27009328 PubMed citation Europe PMC
27056390 PubMed citation Europe PMC
27098797 PubMed citation Europe PMC
27133431 PubMed citation Europe PMC
27145782 PubMed citation Europe PMC
Last Modified
05 March 2018