CHEBI:78741 - oxidopamine

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ChEBI Name oxidopamine ChEBI ID CHEBI:78741 Definition A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). Stars This entity has been manually annotated by the ChEBI Team. Supplier Information ZINC000004096188 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C8H11NO3 Net Charge 0 Average Mass 169.17780 Monoisotopic Mass 169.07389 InChI InChI=1S/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2 InChIKey DIVDFFZHCJEHGG-UHFFFAOYSA-N SMILES NCCc1cc(O)c(O)cc1O Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): neurotoxin A poison that interferes with the functions of the nervous system. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). drug metabolite molecular messenger (via monoamine molecular messenger ) View more via ChEBI Ontology ChEBI Ontology Outgoing oxidopamine (CHEBI:78741) has functional parent dopamine (CHEBI:18243) oxidopamine (CHEBI:78741) has role drug metabolite (CHEBI:49103) oxidopamine (CHEBI:78741) has role human metabolite (CHEBI:77746) oxidopamine (CHEBI:78741) has role neurotoxin (CHEBI:50910) oxidopamine (CHEBI:78741) is a benzenetriol (CHEBI:22707) oxidopamine (CHEBI:78741) is a catecholamine (CHEBI:33567) oxidopamine (CHEBI:78741) is a primary amino compound (CHEBI:50994) IUPAC Name 5-(2-aminoethyl)benzene-1,2,4-triol INNs Sources oxidopamina ChemIDplus oxidopamine WHO MedNet oxidopamine ChemIDplus oxidopaminum ChemIDplus Synonyms Sources 2,4,5-trihydroxyphenethylamine ChemIDplus 6-hydroxydopamine ChemIDplus 6-OHDA ChemIDplus hydroxydopamine MetaCyc topamine ChEBI Manual Xrefs Databases CPD-7666 MetaCyc D05294 KEGG DRUG HMDB0001537 HMDB LSM-37081 LINCS Oxidopamine Wikipedia View more database links Registry Number Type Source 2211011 Reaxys Registry Number Reaxys Citations Types Sources 12486162 PubMed citation Europe PMC 22789904 PubMed citation Europe PMC 23358137 PubMed citation Europe PMC 23670213 PubMed citation Europe PMC 23959789 PubMed citation Europe PMC 24277157 PubMed citation Europe PMC 24333330 PubMed citation Europe PMC 24885281 PubMed citation Europe PMC 8255370 PubMed citation Europe PMC Last Modified 26 February 2016