CHEBI:68844 - phosphodiesterase IV inhibitor

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ChEBI Name phosphodiesterase IV inhibitor ChEBI ID CHEBI:68844 Definition An EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor that specifically blocks the action of phosphodiesterase IV. Stars This entity has been manually annotated by the ChEBI Team. Wikipedia License A phosphodiesterase-4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine monophosphate (cAMP). It is a member of the larger family of PDE inhibitors. The PDE4 family of enzymes are the most prevalent PDE in immune cells. They are predominantly responsible for hydrolyzing cAMP within both immune cells and cells in the central nervous system. Read full article at Wikipedia ChEBI Ontology Outgoing phosphodiesterase IV inhibitor (CHEBI:68844) is a EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor (CHEBI:77758) Incoming apremilast (CHEBI:78540) has role phosphodiesterase IV inhibitor (CHEBI:68844) crisaborole (CHEBI:134677) has role phosphodiesterase IV inhibitor (CHEBI:68844) etazolate (CHEBI:138502) has role phosphodiesterase IV inhibitor (CHEBI:68844) piclamilast (CHEBI:47619) has role phosphodiesterase IV inhibitor (CHEBI:68844) roflumilast (CHEBI:47657) has role phosphodiesterase IV inhibitor (CHEBI:68844) SCH-351591 (CHEBI:77774) has role phosphodiesterase IV inhibitor (CHEBI:68844) Synonyms Sources PDE4 inhibitor ChEBI PDE4 inhibitors ChEBI phosphodiesterase 4 inhibitor ChEBI phosphodiesterase 4 inhibitors ChEBI phosphodiesterase IV inhibitors ChEBI type 4 phosphodiesterase inhibitor ChEBI type 4 phosphodiesterase inhibitors ChEBI Manual Xref Database Phosphodiesterase-4_inhibitor Wikipedia View more database links Last Modified 22 February 2017