rasagiline (CHEBI:63620)

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ChEBI Name	rasagiline

ChEBI ID	CHEBI:63620

Definition	An indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Anonymous

Supplier Information	ChemicalBook:CB2459598, eMolecules:2727012, ZINC000019875504

Download	Molfile XML SDF

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Formula

C12H13N

Net Charge

Average Mass

171.23830

Monoisotopic Mass

171.10480

InChI

InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1

InChIKey

RUOKEQAAGRXIBM-GFCCVEGCSA-N

SMILES

C#CCN[C@@H]1CCc2ccccc12

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	EC 1.4.3.4 (monoamine oxidase) inhibitor An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).

Application(s):	neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders.

ChEBI Ontology
Outgoing	rasagiline (CHEBI:63620) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623) rasagiline (CHEBI:63620) has role neuroprotective agent (CHEBI:63726) rasagiline (CHEBI:63620) is a indanes (CHEBI:46940) rasagiline (CHEBI:63620) is a secondary amine (CHEBI:32863) rasagiline (CHEBI:63620) is a terminal acetylenic compound (CHEBI:73477)

IUPAC Name

(1R)-N-(prop-2-yn-1-yl)indan-1-amine

INN	Source
rasagiline	KEGG DRUG

Citations

Last Modified

02 May 2013