CHEBI:50919 - antiemetic

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ChEBI Name antiemetic
ChEBI ID CHEBI:50919
Definition A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
Stars This entity has been manually annotated by the ChEBI Team.
Wikipedia License
Proton-pump inhibitors (PPIs) are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H+/K+ ATPase proton pump. The body eventually synthesizes new proton pumps to replace the irreversibly inhibited ones, a process driven by normal cellular turnover, which gradually restores acid production. Proton-pump inhibitors have largely superseded the H2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI. A newer PCAB vonoprazan with a faster and longer lasting action than revaprazan, and PPIs has been marketed in Japan (2013), Russia (2021), and the US (2023). PPIs are among the most widely sold medications in the world. The class of proton-pump inhibitor medications is on the World Health Organization's List of Essential Medicines. Omeprazole is the specific listed example.
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ChEBI Ontology
Outgoing antiemetic (CHEBI:50919) is a drug (CHEBI:23888)
Incoming (S)-(−)-sulpiride (CHEBI:64119) has role antiemetic (CHEBI:50919)
6α-methylprednisolone (CHEBI:6888) has role antiemetic (CHEBI:50919)
Akynzeo (CHEBI:85154) has role antiemetic (CHEBI:50919)
alosetron (CHEBI:253342) has role antiemetic (CHEBI:50919)
alosetron hydrochloride (CHEBI:53783) has role antiemetic (CHEBI:50919)
aprepitant (CHEBI:499361) has role antiemetic (CHEBI:50919)
benzquinamide (CHEBI:27662) has role antiemetic (CHEBI:50919)
buclizine (CHEBI:3205) has role antiemetic (CHEBI:50919)
buclizine dihydrochloride (CHEBI:61193) has role antiemetic (CHEBI:50919)
carfenazine (CHEBI:51235) has role antiemetic (CHEBI:50919)
carphenazine maleate (CHEBI:51241) has role antiemetic (CHEBI:50919)
chlorpromazine (CHEBI:3647) has role antiemetic (CHEBI:50919)
chlorprothixene (CHEBI:3651) has role antiemetic (CHEBI:50919)
chlorprothixene hydrochloride (CHEBI:180502) has role antiemetic (CHEBI:50919)
cinnarizine (CHEBI:31403) has role antiemetic (CHEBI:50919)
cyclizine (CHEBI:3994) has role antiemetic (CHEBI:50919)
cyclizine hydrochloride (CHEBI:51045) has role antiemetic (CHEBI:50919)
dexamethasone (CHEBI:41879) has role antiemetic (CHEBI:50919)
dimenhydrinate (CHEBI:4604) has role antiemetic (CHEBI:50919)
diphenhydramine (CHEBI:4636) has role antiemetic (CHEBI:50919)
diphenhydramine hydrochloride (CHEBI:4637) has role antiemetic (CHEBI:50919)
diphenhydramine salicylate (CHEBI:34720) has role antiemetic (CHEBI:50919)
diphenidol (CHEBI:4638) has role antiemetic (CHEBI:50919)
dithiadene (CHEBI:167625) has role antiemetic (CHEBI:50919)
domperidone (CHEBI:31515) has role antiemetic (CHEBI:50919)
domperidone maleate (CHEBI:59812) has role antiemetic (CHEBI:50919)
doxylamine (CHEBI:51380) has role antiemetic (CHEBI:50919)
droperidol (CHEBI:4717) has role antiemetic (CHEBI:50919)
fabesetron (CHEBI:31588) has role antiemetic (CHEBI:50919)
fosaprepitant (CHEBI:64321) has role antiemetic (CHEBI:50919)
fosaprepitant dimeglumine (CHEBI:64311) has role antiemetic (CHEBI:50919)
granisetron (CHEBI:5537) has role antiemetic (CHEBI:50919)
haloperidol (CHEBI:5613) has role antiemetic (CHEBI:50919)
metoclopramide (CHEBI:107736) has role antiemetic (CHEBI:50919)
metoclopramide dihydrochloride monohydrate (CHEBI:60906) has role antiemetic (CHEBI:50919)
metoclopramide hydrochloride (CHEBI:6899) has role antiemetic (CHEBI:50919)
netupitant (CHEBI:85155) has role antiemetic (CHEBI:50919)
olanzapine (CHEBI:7735) has role antiemetic (CHEBI:50919)
pacatal (CHEBI:59117) has role antiemetic (CHEBI:50919)
pachypodol (CHEBI:70007) has role antiemetic (CHEBI:50919)
palonosetron (CHEBI:85161) has role antiemetic (CHEBI:50919)
palonosetron hydrochloride (CHEBI:85157) has role antiemetic (CHEBI:50919)
perphenazine (CHEBI:8028) has role antiemetic (CHEBI:50919)
prochlorperazine (CHEBI:8435) has role antiemetic (CHEBI:50919)
promazine (CHEBI:8459) has role antiemetic (CHEBI:50919)
promethazine (CHEBI:8461) has role antiemetic (CHEBI:50919)
promethazine hydrochloride (CHEBI:8462) has role antiemetic (CHEBI:50919)
propofol (CHEBI:44915) has role antiemetic (CHEBI:50919)
rolapitant (CHEBI:90908) has role antiemetic (CHEBI:50919)
rolapitant hydrochloride (anhydrous) (CHEBI:90912) has role antiemetic (CHEBI:50919)
rolapitant hydrochloride hydrate (CHEBI:90911) has role antiemetic (CHEBI:50919)
scopolamine (CHEBI:16794) has role antiemetic (CHEBI:50919)
scopolamine hydrobromide trihydrate (CHEBI:61272) has role antiemetic (CHEBI:50919)
scopolamine methobromide (CHEBI:61276) has role antiemetic (CHEBI:50919)
sulpiride (CHEBI:32168) has role antiemetic (CHEBI:50919)
thalidomide (CHEBI:9513) has role antiemetic (CHEBI:50919)
thiethylperazine (CHEBI:9544) has role antiemetic (CHEBI:50919)
trifluoperazine (CHEBI:45951) has role antiemetic (CHEBI:50919)
triflupromazine (CHEBI:9711) has role antiemetic (CHEBI:50919)
trimethobenzamide (CHEBI:27796) has role antiemetic (CHEBI:50919)
tropisetron (CHEBI:32269) has role antiemetic (CHEBI:50919)
tropisetron hydrochloride (CHEBI:77570) has role antiemetic (CHEBI:50919)
zingerone (CHEBI:68657) has role antiemetic (CHEBI:50919)
Synonyms Sources
anti-emetic ChEBI
anti-emetics ChEBI
antiemético ChEBI
antiemetics ChEBI
Manual Xref Database
Antiemetic Wikipedia
View more database links
Last Modified
23 September 2021