| Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas, nitrous, or factitious air, among others, is a chemical compound, an oxide of nitrogen with the formula N2O. At room temperature, it is a colourless non-flammable gas, and has a slightly sweet scent and taste. At elevated temperatures, nitrous oxide is a powerful oxidiser similar to molecular oxygen.
Nitrous oxide has significant medical uses, especially in surgery and dentistry, for its anaesthetic and pain-reducing effects, and it is on the World Health Organization's List of Essential Medicines. Its colloquial name, "laughing gas", coined by Humphry Davy, describes the euphoric effects upon inhaling it, which cause it to be used as a recreational drug inducing a brief "high". When abused chronically, it may cause neurological damage through inactivation of vitamin B12. It is also used as an oxidiser in rocket propellants and motor racing fuels, and as a frothing gas for whipped cream.
Nitrous oxide is also an atmospheric pollutant, with a concentration of 333 parts per billion (ppb) in 2020, increasing at 1 ppb annually. It is a major scavenger of stratospheric ozone, with an impact comparable to that of CFCs. About 40% of human-caused emissions are from agriculture, as nitrogen fertilisers are digested into nitrous oxide by soil micro-organisms. As the third most important greenhouse gas, nitrous oxide substantially contributes to global warming. Reduction of emissions is an important goal in the politics of climate change.
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InChI=1S/C21H24F3N3S/c1- 25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 |
| ZEWQUBUPAILYHI-UHFFFAOYSA-N |
| CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 |
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Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
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dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
calmodulin antagonist
An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin.
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12).
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
An EC 5.3.3.* (intramolecular oxidase transposing C2C bonds) inhibitor that interferes with the action of a cholestenol Delta-isomerase (EC 5.3.3.5).
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dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
phenothiazine antipsychotic drug
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View more via ChEBI Ontology
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10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
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trifluoperazina
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ChemIDplus
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trifluoperazine
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KEGG DRUG
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trifluopérazine
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ChEBI
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trifluoperazinum
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ChemIDplus
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10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
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NIST Chemistry WebBook
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10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE
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PDBeChem
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Trifluoperazine
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KEGG COMPOUND
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trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine
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NIST Chemistry WebBook
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trifluoroperazine
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NIST Chemistry WebBook
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trifluperazine
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ChemIDplus
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117-89-5
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CAS Registry Number
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KEGG COMPOUND
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117-89-5
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CAS Registry Number
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ChemIDplus
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117-89-5
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CAS Registry Number
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NIST Chemistry WebBook
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2415561
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Gmelin Registry Number
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Gmelin
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57272
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Beilstein Registry Number
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Beilstein
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57272
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Reaxys Registry Number
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Reaxys
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11121417
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PubMed citation
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Europe PMC
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14974020
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PubMed citation
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Europe PMC
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15722405
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PubMed citation
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Europe PMC
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1650428
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PubMed citation
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Europe PMC
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19277699
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PubMed citation
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Europe PMC
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19747949
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PubMed citation
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Europe PMC
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20544963
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PubMed citation
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Europe PMC
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7404501
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PubMed citation
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Europe PMC
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9730919
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PubMed citation
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Europe PMC
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2014-07-14
