CHEBI:35374 - D-mannose 1-phosphate

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ChEBI Name D-mannose 1-phosphate ChEBI ID CHEBI:35374 ChEBI ASCII Name D-mannose 1-phosphate Definition A mannose phosphate that is D-mannose carrying a phosphate group at position 1. Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:21058, CHEBI:4210 Supplier Information ChemicalBook:CB4365169, eMolecules:499483 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins. Leucine is an α-amino acid, meaning it contains an α-amino group (which is in the protonated −NH3+ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and a side chain isobutyl group, making it a non-polar aliphatic amino acid. It is essential in humans, meaning the body cannot synthesize it; it must be obtained from the diet. Human dietary sources are foods that contain protein, such as meats, dairy products, soy products, and beans and other legumes. It is encoded by the codons UUA, UUG, CUU, CUC, CUA, and CUG. Leucine is named after the Greek word for "white": λευκός (leukós, "white"), after its common appearance as a white powder, a property it shares with many other amino acids. Like valine and isoleucine, leucine is a branched-chain amino acid. The primary metabolic end products of leucine metabolism are acetyl-CoA and acetoacetate; consequently, it is one of the two exclusively ketogenic amino acids, with lysine being the other. It is the most important ketogenic amino acid in humans. Leucine and β-hydroxy β-methylbutyric acid, a minor leucine metabolite, exhibit pharmacological activity in humans and have been demonstrated to promote protein biosynthesis via the phosphorylation of the mechanistic target of rapamycin (mTOR). Read full article at Wikipedia Formula C6H13O9P Net Charge 0 Average Mass 260.13578 Monoisotopic Mass 260.02972 InChI InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5+,6?/m1/s1 InChIKey HXXFSFRBOHSIMQ-QTVWNMPRSA-N SMILES OC[C@H]1OC(OP(O)(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O Metabolite of Species Details Saccharomyces cerevisiae (NCBI:txid4932) Source: yeast.sf.net See: PubMed Homo sapiens (NCBI:txid9606) See: DOI Roles Classification Biological Role(s): fundamental metabolite Any metabolite produced by all living cells. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). View more via ChEBI Ontology ChEBI Ontology Outgoing D-mannose 1-phosphate (CHEBI:35374) has functional parent D-mannopyranose (CHEBI:4208) D-mannose 1-phosphate (CHEBI:35374) has role fundamental metabolite (CHEBI:78675) D-mannose 1-phosphate (CHEBI:35374) has role human metabolite (CHEBI:77746) D-mannose 1-phosphate (CHEBI:35374) is a mannose phosphate (CHEBI:21060) Incoming α-D-mannose 1-phosphate (CHEBI:18205) is a D-mannose 1-phosphate (CHEBI:35374) IUPAC Name D-mannopyranose 1-(dihydrogen phosphate) Synonyms Sources D-Mannose 1-phosphate KEGG COMPOUND D-mannose 1-phosphates ChEBI Mannose 1-phosphate ChemIDplus Manual Xrefs Databases C00007389 KNApSAcK C00636 KEGG COMPOUND DB02867 DrugBank ECMDB01436 ECMDB HMDB0006330 HMDB Mannose_1-phosphate Wikipedia YMDB00386 YMDB View more database links Registry Number Type Source 27251-84-9 CAS Registry Number ChemIDplus Citation Last Modified 21 January 2016