| tolvaptan |
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| CHEBI:32246 |
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| A racemate comprising of equimolar amounts of (R)- and (S)-tolvaptan. It is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency. |
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This entity has been manually annotated by the ChEBI Team.
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vasopressin receptor antagonist
Any drug which blocks vasopressin receptors.
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aquaretic
A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
vasopressin receptor antagonist
Any drug which blocks vasopressin receptors.
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View more via ChEBI Ontology
rac- N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
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tolvaptán
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WHO MedNet
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tolvaptan
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WHO MedNet
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tolvaptan
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WHO MedNet
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tolvaptanum
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WHO MedNet
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(±)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide
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ChEBI
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(±)-tolvaptan
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ChEBI
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(RS)-tolvaptan
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ChEBI
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N-(4-{[(5RS)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide
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IUPAC
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OPC 41061
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DrugCentral
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OPC-41061
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DrugCentral
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RS-tolvaptan
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ChEBI
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Jinarc
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DrugBank
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Jynarque
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DrugBank
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Samsca
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KEGG DRUG
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150683-30-0
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CAS Registry Number
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ChemIDplus
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