CHEBI:28300 - glutamine

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ChEBI Name glutamine ChEBI ID CHEBI:28300 Definition An α-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4. Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:5432, CHEBI:24316 Supplier Information ChemicalBook:CB6705020, eMolecules:518145, eMolecules:883971, ZINC000006661227 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License l-DOPA, also known as l-3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants and animals, including humans. Humans, as well as a portion of the other animals that utilize l-DOPA, make it via biosynthesis from the amino acid l-tyrosine. l-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. Furthermore, l-DOPA itself mediates neurotrophic factor release by the brain and CNS. In some plant families (of the order Caryophyllales), l-DOPA is the central precursor of a biosynthetic pathway that produces a class of pigments called betalains. l-DOPA can be manufactured and in its pure form is sold as a drug with the INNTooltip International Nonproprietary Name levodopa. Trade names include Sinemet, Pharmacopa, Atamet, and Stalevo. As a drug, it is used in the treatment of Parkinson's disease and dopamine-responsive dystonia, as well as restless leg syndrome. l-DOPA has a counterpart with opposite chirality, d-DOPA. As is true for many molecules, the human body produces only one of these isomers (the l-DOPA form). The enantiomeric purity of l-DOPA may be analyzed by determination of the optical rotation or by chiral thin-layer chromatography. Read full article at Wikipedia Formula C5H10N2O3 Net Charge 0 Average Mass 146.14458 Monoisotopic Mass 146.06914 InChI InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10) InChIKey ZDXPYRJPNDTMRX-UHFFFAOYSA-N SMILES NC(CCC(N)=O)C(O)=O Metabolite of Species Details Daphnia magna (NCBI:txid35525) See: PubMed Arabidopsis thaliana (NCBI:txid3702) See: PubMed Homo sapiens (NCBI:txid9606) See: PubMed Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid ) Biological Role(s): fundamental metabolite Any metabolite produced by all living cells. View more via ChEBI Ontology ChEBI Ontology Outgoing glutamine (CHEBI:28300) has part 3-amino-3-oxopropyl group (CHEBI:50331) glutamine (CHEBI:28300) has role fundamental metabolite (CHEBI:78675) glutamine (CHEBI:28300) is a α-amino acid (CHEBI:33704) glutamine (CHEBI:28300) is a polar amino acid (CHEBI:26167) glutamine (CHEBI:28300) is conjugate acid of glutaminate (CHEBI:32678) glutamine (CHEBI:28300) is conjugate base of glutaminium (CHEBI:32679) Incoming N2-phenylacetylglutamine (CHEBI:8087) has functional parent glutamine (CHEBI:28300) glutamine derivative (CHEBI:70813) has functional parent glutamine (CHEBI:28300) D-glutamine (CHEBI:17061) is a glutamine (CHEBI:28300) L-glutamine (CHEBI:18050) is a glutamine (CHEBI:28300) glutaminium (CHEBI:32679) is conjugate acid of glutamine (CHEBI:28300) glutaminate (CHEBI:32678) is conjugate base of glutamine (CHEBI:28300) N2-glutamino group (CHEBI:21816) is substituent group from glutamine (CHEBI:28300) N5-glutamino group (CHEBI:21847) is substituent group from glutamine (CHEBI:28300) glutamine residue (CHEBI:32677) is substituent group from glutamine (CHEBI:28300) glutaminyl group (CHEBI:24320) is substituent group from glutamine (CHEBI:28300) IUPAC Name glutamine Synonyms Sources 2,5-diamino-5-oxopentanoic acid IUPAC 2-amino-4-carbamoylbutanoic acid JCBN 2-Aminoglutaramic acid KEGG COMPOUND glutamic acid γ-amide ChEBI Glutamin ChEBI Glutamine KEGG COMPOUND Glutaminsäure-5-amid ChEBI Hgln IUPAC Manual Xrefs Databases C00001359 KNApSAcK C00303 KEGG COMPOUND Glutamine Wikipedia View more database links Registry Numbers Types Sources 1723795 Reaxys Registry Number Reaxys 27318 Gmelin Registry Number Gmelin 585-21-7 CAS Registry Number ChemIDplus 6899-04-3 CAS Registry Number ChemIDplus Last Modified 06 July 2021