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> Main
CHEBI:2453 - acyclovir
Main
ChEBI Ontology
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ChEBI Name
acyclovir
ChEBI ID
CHEBI:2453
Definition
An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.
Stars
This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs
CHEBI:40459
Supplier Information
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Wikipedia
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Read full article at Wikipedia
Formula
C8H11N5O3
Net Charge
0
Average Mass
225.20460
Monoisotopic Mass
225.08619
InChI
InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChIKey
MKUXAQIIEYXACX-UHFFFAOYSA-N
SMILES
Nc1nc2n(COCCO)cnc2c(=O)[nH]1
Roles Classification
Biological Role
(s):
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
antimetabolite
A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
Application
(s):
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
acyclovir (
CHEBI:2453
)
has functional parent
guanine (
CHEBI:16235
)
acyclovir (
CHEBI:2453
)
has role
antimetabolite (
CHEBI:35221
)
acyclovir (
CHEBI:2453
)
has role
antiviral drug (
CHEBI:36044
)
acyclovir (
CHEBI:2453
)
is a
2-aminopurines (
CHEBI:20702
)
acyclovir (
CHEBI:2453
)
is a
oxopurine (
CHEBI:25810
)
IUPAC Name
2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6
H
-purin-6-one
INNs
Sources
aciclovir
ChEBI
aciclovirum
ChemIDplus
Synonym
Source
acycloguanosine
ChEBI
Brand Name
Source
Zovir
DrugBank
Manual Xrefs
Databases
85
DrugCentral
AC2
PDBeChem
Acyclovir
Wikipedia
C06810
KEGG COMPOUND
D00222
KEGG DRUG
DB00787
DrugBank
DE2539963
Patent
HMDB0014925
HMDB
LSM-5459
LINCS
US4199574
Patent
View more database links
Registry Numbers
Types
Sources
1219402
Reaxys Registry Number
Reaxys
1219402
Beilstein Registry Number
Beilstein
59277-89-3
CAS Registry Number
KEGG COMPOUND
59277-89-3
CAS Registry Number
ChemIDplus
Citations
Types
Sources
11687127
PubMed citation
Europe PMC
11994034
PubMed citation
Europe PMC
24346595
PubMed citation
Europe PMC
26024233
PubMed citation
Europe PMC
28166217
PubMed citation
Europe PMC
8308511
PubMed citation
Europe PMC
Last Modified
13 June 2017