icosanoid (CHEBI:23899)

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CHEBI:23899 - icosanoid

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ChEBI Name	icosanoid

ChEBI ID	CHEBI:23899

Definition	Any member of the group of signalling molecules arising from oxidation of the three C₂₀ essential fatty acids (EFAs) icosapentaenoic acid (EPA), arachidonic acid (AA) and dihomo-gamma-linolenic acid (DGLA).

Stars	This entity has been manually annotated by the ChEBI Team.

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ChEBI Ontology
Outgoing	icosanoid (CHEBI:23899) is a fatty acid derivative (CHEBI:61697) icosanoid (CHEBI:23899) is conjugate acid of icosanoid anion (CHEBI:62937)

Incoming	(+/-)11-HEDE (CHEBI:183029) is a icosanoid (CHEBI:23899) (15E,17E)-9,10,12,13-tetrahydroxyhenicosa-15,17-dienoic acid (CHEBI:206022) is a icosanoid (CHEBI:23899) (2R)-2-Hydroxy-3-(icosanoyloxy)propyl (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoate (CHEBI:185216) is a icosanoid (CHEBI:23899) (5Z,9E,12S,14Z)-8,11,12,20-tetrahydroxyicosa-5,9,14-trienoic acid (CHEBI:83782) is a icosanoid (CHEBI:23899) (6E,8Z,10E,12S,14Z)-12-hydroxy-5-oxoicosatetraenoic acid (CHEBI:137749) is a icosanoid (CHEBI:23899) (6E,8Z,11Z,13E,15S)-15-hydroxy-5-oxoicosatetraenoic acid (CHEBI:137746) is a icosanoid (CHEBI:23899) (6E,8Z,11Z,14Z,17Z)-5-oxoicosapentaenoic acid (CHEBI:140244) is a icosanoid (CHEBI:23899) (7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoic acid (CHEBI:75825) is a icosanoid (CHEBI:23899) 11R-HEDE (CHEBI:165294) is a icosanoid (CHEBI:23899) 11S-HEDE (CHEBI:165295) is a icosanoid (CHEBI:23899) 12-HPE(8,10,14)TrE (CHEBI:84174) is a icosanoid (CHEBI:23899) 12-Keto-tetrahydro-LTB4 (CHEBI:165291) is a icosanoid (CHEBI:23899) 13,14-dihydro-15-oxolipoxin A₄ (CHEBI:63993) is a icosanoid (CHEBI:23899) 13,14-dihydrolipoxin A₄ (CHEBI:79199) is a icosanoid (CHEBI:23899) 14-carboxy-15,16,17,18,19,20-hexanor-leukotriene E₃ (CHEBI:74019) is a icosanoid (CHEBI:23899) 15R-HEDE (CHEBI:165296) is a icosanoid (CHEBI:23899) 16-carboxy-Δ¹³-17,18,19,20-tetranor-leukotriene E₄ (CHEBI:74016) is a icosanoid (CHEBI:23899) 16-carboxy-17,18,19,20-tetranor-leukotriene E₃ (CHEBI:74014) is a icosanoid (CHEBI:23899) 18-carboxy-19,20-dinor-leukotriene E₄ (CHEBI:74017) is a icosanoid (CHEBI:23899) 5(S),6(S)-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid (CHEBI:132909) is a icosanoid (CHEBI:23899) 5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid (CHEBI:136355) is a icosanoid (CHEBI:23899) 5,20-diHEPE (CHEBI:130073) is a icosanoid (CHEBI:23899) 5,8,11-icosatriynoic acid (CHEBI:53454) is a icosanoid (CHEBI:23899) Auricolic acid (CHEBI:186663) is a icosanoid (CHEBI:23899) bis(hydroperoxy)icosatetraenoic acid (CHEBI:138293) is a icosanoid (CHEBI:23899) CA-phytotoxin (CHEBI:199165) is a icosanoid (CHEBI:23899) CDP-DG(20:2(11Z,14Z)/6 keto-PGF1alpha) (CHEBI:230060) is a icosanoid (CHEBI:23899) CDP-DG(20:3(5Z,8Z,11Z)/PGE1) (CHEBI:230082) is a icosanoid (CHEBI:23899) CDP-DG(20:4(5Z,8Z,11Z,14Z)/PGF2alpha) (CHEBI:230063) is a icosanoid (CHEBI:23899) CDP-DG(22:3(10Z,13Z,16Z)/5-iso PGF2VI) (CHEBI:230083) is a icosanoid (CHEBI:23899) CDP-DG(22:3(10Z,13Z,16Z)/PGE2) (CHEBI:230912) is a icosanoid (CHEBI:23899) CDP-DG(PGE2/20:2(11Z,14Z)) (CHEBI:230190) is a icosanoid (CHEBI:23899) CDP-DG(PGE2/20:3(5Z,8Z,11Z)) (CHEBI:230051) is a icosanoid (CHEBI:23899) CDP-DG(PGE2/22:3(10Z,13Z,16Z)) (CHEBI:230104) is a icosanoid (CHEBI:23899) CDP-DG(PGF1alpha/22:3(10Z,13Z,16Z)) (CHEBI:230365) is a icosanoid (CHEBI:23899) CDP-DG(PGJ2/20:2(11Z,14Z)) (CHEBI:230128) is a icosanoid (CHEBI:23899) DG(13:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) (CHEBI:231045) is a icosanoid (CHEBI:23899) DG(14:1n5/0:0/20:5n3) (CHEBI:196650) is a icosanoid (CHEBI:23899) DG(15:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) (CHEBI:230398) is a icosanoid (CHEBI:23899) DG(16:1n7/0:0/20:5n3) (CHEBI:178268) is a icosanoid (CHEBI:23899) DG(18:1n7/0:0/20:5n3) (CHEBI:196721) is a icosanoid (CHEBI:23899) DG(18:1n9/0:0/20:5n3) (CHEBI:196727) is a icosanoid (CHEBI:23899) DG(18:2n6/0:0/20:4n3) (CHEBI:196757) is a icosanoid (CHEBI:23899) DG(18:2n6/0:0/20:5n3) (CHEBI:179070) is a icosanoid (CHEBI:23899) DG(18:3n3/0:0/20:4n3) (CHEBI:196695) is a icosanoid (CHEBI:23899) DG(18:3n6/0:0/20:3n6) (CHEBI:196724) is a icosanoid (CHEBI:23899) DG(18:3n6/0:0/20:4n3) (CHEBI:196692) is a icosanoid (CHEBI:23899) DG(18:3n6/0:0/20:4n6) (CHEBI:196686) is a icosanoid (CHEBI:23899) DG(19:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) (CHEBI:231006) is a icosanoid (CHEBI:23899) DG(20:2n6/0:0/18:4n3) (CHEBI:178353) is a icosanoid (CHEBI:23899) DG(20:2n6/0:0/20:4n3) (CHEBI:196759) is a icosanoid (CHEBI:23899) DG(20:2n6/0:0/20:4n6) (CHEBI:196758) is a icosanoid (CHEBI:23899) DG(20:2n6/0:0/20:5n3) (CHEBI:179071) is a icosanoid (CHEBI:23899) DG(20:3n6/0:0/18:3n3) (CHEBI:196728) is a icosanoid (CHEBI:23899) DG(20:3n6/0:0/18:4n3) (CHEBI:196696) is a icosanoid (CHEBI:23899) DG(20:3n6/0:0/20:4n3) (CHEBI:178495) is a icosanoid (CHEBI:23899) DG(20:3n6/0:0/20:4n6) (CHEBI:178494) is a icosanoid (CHEBI:23899) DG(20:3n9/0:0/18:3n3) (CHEBI:196725) is a icosanoid (CHEBI:23899) DG(20:3n9/0:0/18:3n6) (CHEBI:196726) is a icosanoid (CHEBI:23899) DG(20:3n9/0:0/18:4n3) (CHEBI:196691) is a icosanoid (CHEBI:23899) DG(20:3n9/0:0/20:4n3) (CHEBI:178490) is a icosanoid (CHEBI:23899) DG(20:3n9/0:0/20:4n6) (CHEBI:178489) is a icosanoid (CHEBI:23899) DG(20:4n6/0:0/18:3n3) (CHEBI:196697) is a icosanoid (CHEBI:23899) DG(20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/12:0/0:0) (CHEBI:230064) is a icosanoid (CHEBI:23899) DG(8:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) (CHEBI:231212) is a icosanoid (CHEBI:23899) DHET (CHEBI:64005) is a icosanoid (CHEBI:23899) dihydroxyicosatetraenoic acid (CHEBI:72868) is a icosanoid (CHEBI:23899) EET (CHEBI:64007) is a icosanoid (CHEBI:23899) eoxin (CHEBI:193574) is a icosanoid (CHEBI:23899) EpETE (CHEBI:72852) is a icosanoid (CHEBI:23899) HETE (CHEBI:36275) is a icosanoid (CHEBI:23899) HPETE (CHEBI:24644) is a icosanoid (CHEBI:23899) hydroperoxy(epoxy)icosatrienoic acid (CHEBI:134641) is a icosanoid (CHEBI:23899) hydroperoxy(hydroxy)icosapentaenoic acid (CHEBI:134645) is a icosanoid (CHEBI:23899) hydroperoxy(hydroxy)icosatetraenoic acid (CHEBI:138327) is a icosanoid (CHEBI:23899) Hydroperoxy-eicosadienoic acid (CHEBI:176390) is a icosanoid (CHEBI:23899) hydroperoxyicosapentaenoic acid (CHEBI:138392) is a icosanoid (CHEBI:23899) hydroperoxyicosatrienoic acid (CHEBI:136627) is a icosanoid (CHEBI:23899) icosenoic acid (CHEBI:23902) is a icosanoid (CHEBI:23899) isoprostane (CHEBI:138408) is a icosanoid (CHEBI:23899) leukotriene (CHEBI:25029) is a icosanoid (CHEBI:23899) levuglandin (CHEBI:36142) is a icosanoid (CHEBI:23899) methyl 6-hydroperoxy-4,8,11,14,17-eicosapentaenoate (CHEBI:197271) is a icosanoid (CHEBI:23899) methyl 8-hydroperoxy-5,9,11,14,17-eicosapentaenoate (CHEBI:197244) is a icosanoid (CHEBI:23899) methyl 9-hydroperoxy-5,7,11,14,17-eicosapentaenoate (CHEBI:197269) is a icosanoid (CHEBI:23899) Mycestericin A (CHEBI:204784) is a icosanoid (CHEBI:23899) Myriocin-12-en (CHEBI:181458) is a icosanoid (CHEBI:23899) nonclassic icosanoid (CHEBI:61703) is a icosanoid (CHEBI:23899) PI(20:2(11Z,14Z)/PGF2alpha) (CHEBI:230947) is a icosanoid (CHEBI:23899) PI(20:3(5Z,8Z,11Z)/PGE1) (CHEBI:230957) is a icosanoid (CHEBI:23899) PI(20:3(5Z,8Z,11Z)/PGF1alpha) (CHEBI:231096) is a icosanoid (CHEBI:23899) PI(20:3(5Z,8Z,11Z)/PGF2alpha) (CHEBI:231002) is a icosanoid (CHEBI:23899) PI(20:4(5Z,8Z,11Z,14Z)/PGJ2) (CHEBI:230929) is a icosanoid (CHEBI:23899) PI(22:3(10Z,13Z,16Z)/PGE1) (CHEBI:230265) is a icosanoid (CHEBI:23899) PI(22:3(10Z,13Z,16Z)/PGF1alpha) (CHEBI:231046) is a icosanoid (CHEBI:23899) PI(22:3(10Z,13Z,16Z)/TXB2) (CHEBI:230222) is a icosanoid (CHEBI:23899) PI(6 keto-PGF1alpha/20:2(11Z,14Z)) (CHEBI:230896) is a icosanoid (CHEBI:23899) PI(PGE2/20:4(5Z,8Z,11Z,14Z)) (CHEBI:231050) is a icosanoid (CHEBI:23899) PI(PGE2/22:3(10Z,13Z,16Z)) (CHEBI:230376) is a icosanoid (CHEBI:23899) PI(PGJ2/20:3(5Z,8Z,11Z)) (CHEBI:231085) is a icosanoid (CHEBI:23899) PI(TXB2/22:3(10Z,13Z,16Z)) (CHEBI:230273) is a icosanoid (CHEBI:23899) prostanoid (CHEBI:26347) is a icosanoid (CHEBI:23899) icosanoid anion (CHEBI:62937) is conjugate base of icosanoid (CHEBI:23899)

Synonyms	Sources
eicosanoid	ChEBI
eicosanoids	ChEBI
icosanoid	LIPID MAPS
icosanoids	ChEBI

Manual Xrefs	Databases
Eicosanoid	Wikipedia
LMFA03	LIPID MAPS
View more database links

Citations

Last Modified

05 March 2018

General Comments
2011-03-23	A particular eicosanoid is denoted by a four-character abbreviation, composed of: (i)its two-letter abbreviation; (ii) one A-B-C sequence letter; and (iii) a subscript, indicating the number of double bonds.
2011-03-23	Functioning as autocrine hormones, they exert complex control over a wide diversity of physiological processes, mainly in inflammation or immunity.
2011-03-24	Current usage limits the term to the leukotrienes (LT) and the prostanoids (prostaglandins (PG), prostacyclins (PGI) and thromboxanes (TX)).