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InChI=1S/CH4O/c1-2/h2H,1H3
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ChEBI
> Main
CHEBI:19138 - 12-HETE
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ChEBI Ontology
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ChEBI Name
12-HETE
ChEBI ID
CHEBI:19138
Definition
A HETE that is icosa-5,8,10,14-tetraenoic acid substituted by a hydroxy group at position 12. It is a metabolite of arachidonic acid.
Stars
This entity has been manually annotated by the ChEBI Team.
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Formula
C20H32O3
Net Charge
0
Average Mass
320.46628
Monoisotopic Mass
320.23514
InChI
InChI=1S/C20H32O3/c1-
2-
3-
4-
5-
10-
13-
16-
19(21)
17-
14-
11-
8-
6-
7-
9-
12-
15-
18-
20(22)
23/h7-
11,13-
14,17,19,21H,2-
6,12,15-
16,18H2,1H3,(H,22,23)
InChIKey
ZNHVWPKMFKADKW-UHFFFAOYSA-N
SMILES
[H]C(CCCC(O)=O)=CCC([H])=CC([H])=CC(O)CC([H])=CCCCCC
Roles Classification
Chemical Role
(s):
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Br
o
nsted base).
(via
oxoacid
)
Biological Role
(s):
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (
Homo sapiens
).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
12-HETE (
CHEBI:19138
)
has functional parent
icosa-5,8,10,14-tetraenoic acid (
CHEBI:36039
)
12-HETE (
CHEBI:19138
)
has role
human metabolite (
CHEBI:77746
)
12-HETE (
CHEBI:19138
)
is a
HETE (
CHEBI:36275
)
Incoming
(5
Z
,8
Z
,10
E
,14
Z
)-12-hydroxyicosatetraenoic acid (
CHEBI:84447
)
is a
12-HETE (
CHEBI:19138
)
Synonyms
Sources
12-hydroxy-5,8,10,14-eicosatetraenoic acid
ChEBI
12-hydroxy-5,8,10,14-icosatetraenoic acid
ChEBI
Manual Xref
Database
HMDB0006111
HMDB
View more database links
Citations
Types
Sources
24685839
PubMed citation
Europe PMC
8207335
PubMed citation
Europe PMC
Last Modified
23 October 2015