CHEBI:18295 - histamine

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ChEBI Name histamine
ChEBI ID CHEBI:18295
Definition A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:43187, CHEBI:817, CHEBI:14401, CHEBI:24596
Supplier Information ChemicalBook:CB3326778, eMolecules:518114, eMolecules:1844537, ZINC000000388081
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Formula C5H9N3
Net Charge 0
Average Mass 111.14518
Monoisotopic Mass 111.07965
InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChIKey NTYJJOPFIAHURM-UHFFFAOYSA-N
SMILES NCCc1c[nH]cn1
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Mus musculus (NCBI:txid10090) See: PubMed
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
neurotransmitter
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing histamine (CHEBI:18295) has role human metabolite (CHEBI:77746)
histamine (CHEBI:18295) has role mouse metabolite (CHEBI:75771)
histamine (CHEBI:18295) has role neurotransmitter (CHEBI:25512)
histamine (CHEBI:18295) is a aralkylamino compound (CHEBI:64365)
histamine (CHEBI:18295) is a imidazoles (CHEBI:24780)
histamine (CHEBI:18295) is conjugate base of histaminium (CHEBI:58432)
Incoming α-methylhistamine (CHEBI:74759) has functional parent histamine (CHEBI:18295)
2-methylhistamine (CHEBI:74761) has functional parent histamine (CHEBI:18295)
4-methylhistamine (CHEBI:74760) has functional parent histamine (CHEBI:18295)
N-acetylhistamine (CHEBI:28483) has functional parent histamine (CHEBI:18295)
N-guanylhistamine (CHEBI:28021) has functional parent histamine (CHEBI:18295)
N-hydroxyhistamine (CHEBI:196952) has functional parent histamine (CHEBI:18295)
Nα-γ-L-glutamylhistamine (CHEBI:30307) has functional parent histamine (CHEBI:18295)
Nτ-methylhistamine (CHEBI:29009) has functional parent histamine (CHEBI:18295)
carcinine (CHEBI:131429) has functional parent histamine (CHEBI:18295)
testosterone-3-CMO-Hist (CHEBI:60303) has functional parent histamine (CHEBI:18295)
histamine phosphate (CHEBI:51193) has part histamine (CHEBI:18295)
histaminium (CHEBI:58432) is conjugate acid of histamine (CHEBI:18295)
IUPAC Name
2-(1H-imidazol-4-yl)ethanamine
Synonyms Sources
1H-Imidazole-4-ethanamine KEGG COMPOUND
2-(4-Imidazolyl)ethylamine KEGG COMPOUND
Histamine KEGG COMPOUND
HISTAMINE PDBeChem
Manual Xrefs Databases
1375 DrugCentral
C00001414 KNApSAcK
C00388 KEGG COMPOUND
D08040 KEGG DRUG
Histamine Wikipedia
HISTAMINE MetaCyc
HMDB0000870 HMDB
HSM PDBeChem
View more database links
Registry Numbers Types Sources
2012 Reaxys Registry Number Reaxys
2968 Gmelin Registry Number Gmelin
51-45-6 CAS Registry Number KEGG COMPOUND
51-45-6 CAS Registry Number NIST Chemistry WebBook
51-45-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
16399866 PubMed citation Europe PMC
19547708 PubMed citation Europe PMC
19843401 PubMed citation Europe PMC
22770225 PubMed citation Europe PMC
24101735 PubMed citation Europe PMC
Last Modified
22 February 2017