CHEBI:17515 - L-γ-glutamyl-L-cysteine

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ChEBI Name L-γ-glutamyl-L-cysteine ChEBI ID CHEBI:17515 ChEBI ASCII Name L-gamma-glutamyl-L-cysteine Definition A molecular entity formed when L-cysteine amino group binds to the γ-carbonyl of L-glutamic acid. Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:39975, CHEBI:10566, CHEBI:10570, CHEBI:12400, CHEBI:12404, CHEBI:17971, CHEBI:24185, CHEBI:24194 Supplier Information eMolecules:537269, ZINC000004543724 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Docosatetraenoic acid designates any straight chain 22:4 fatty acid. (See Essential fatty acid for nomenclature.) One isomer is of particular interest: all-cis-7,10,13,16-docosatetraenoic acid is an ω-6 fatty acid with the common name adrenic acid (AdA). This is a naturally occurring polyunsaturated fatty acid formed through a 2-carbon chain elongation of arachidonic acid. It is one of the most abundant fatty acids in the early human brain. This unsaturated fatty acid is also metabolized by cells to biologically active products viz., dihomoprostaglandins, and epoxydocosatrienoic acids (EDTs, also known as dihomo-EETs). In addition to being endothelium-derived hyperpolarizing factors, EDTs have demonstrated anti-endoplasmic reticulum stress and anti-nociceptive activities. They are hydrolyzed by the soluble epoxide hydrolase (sEH) to dihydroxydocosatrienoic acids (DHDTs) and hence might play a role in the efficacy of sEH inhibitors. Read full article at Wikipedia Formula C8H14N2O5S Net Charge 0 Average Mass 250.27324 Monoisotopic Mass 250.06234 InChI InChI=1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1 InChIKey RITKHVBHSGLULN-WHFBIAKZSA-N SMILES N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O Metabolite of Species Details Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed Escherichia coli (NCBI:txid562) See: PubMed Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. View more via ChEBI Ontology ChEBI Ontology Outgoing L-γ-glutamyl-L-cysteine (CHEBI:17515) has functional parent L-cysteine (CHEBI:17561) L-γ-glutamyl-L-cysteine (CHEBI:17515) has functional parent L-glutamic acid (CHEBI:16015) L-γ-glutamyl-L-cysteine (CHEBI:17515) has role Escherichia coli metabolite (CHEBI:76971) L-γ-glutamyl-L-cysteine (CHEBI:17515) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) L-γ-glutamyl-L-cysteine (CHEBI:17515) has role human metabolite (CHEBI:77746) L-γ-glutamyl-L-cysteine (CHEBI:17515) has role mouse metabolite (CHEBI:75771) L-γ-glutamyl-L-cysteine (CHEBI:17515) is a gamma-glutamylcysteine (CHEBI:24195) L-γ-glutamyl-L-cysteine (CHEBI:17515) is conjugate acid of L-γ-glutamyl-L-cysteinate(1−) (CHEBI:58173) Incoming DON-10-gamma-glutamylcysteine (CHEBI:149450) has functional parent L-γ-glutamyl-L-cysteine (CHEBI:17515) L-γ-glutamyl-L-cysteinate(1−) (CHEBI:58173) is conjugate base of L-γ-glutamyl-L-cysteine (CHEBI:17515) IUPAC Name L-γ-glutamyl-L-cysteine Synonyms Sources 5-L-Glutamyl-L-cysteine KEGG COMPOUND gamma-Glu-Cys ChEBI gamma-Glutamylcysteine KEGG COMPOUND gamma-L-Glutamyl-L-cysteine KEGG COMPOUND γGluCys ChEBI Glu(-Cys) JCBN L-gamma-glutamyl-L-cysteine PDBeChem L-gamma-Glutamylcysteine KEGG COMPOUND Manual Xrefs Databases C00007507 KNApSAcK C00669 KEGG COMPOUND DB03408 DrugBank Gamma-Glutamylcysteine Wikipedia HMDB0001049 HMDB L-GAMMA-GLUTAMYLCYSTEINE MetaCyc View more database links Registry Numbers Types Sources 1729154 Reaxys Registry Number Reaxys 636-58-8 CAS Registry Number ChemIDplus Citation Type Source 11409324 PubMed citation Europe PMC Last Modified 27 January 2016