| Progesterone ( ; P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens and is the major progestogen in the body. Progesterone has a variety of important functions in the body. It is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid.
In addition to its role as a natural hormone, progesterone is also used as a medication, such as in combination with estrogen for contraception, to reduce the risk of uterine or cervical cancer, in hormone replacement therapy, and in feminizing hormone therapy. It was first prescribed in 1934. |
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InChI=1S/C21H30O3/c1- 20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1 |
| ZESRJSPZRDMNHY-YFWFAHHUSA-N |
| [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(=O)CO |
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Mus musculus
(NCBI:txid10090)
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Source: BioModels - MODEL1507180067
See:
PubMed
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Homo sapiens
(NCBI:txid9606)
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See:
DOI
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human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
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View more via ChEBI Ontology
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21-hydroxypregn-4-ene-3,20-dione
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11-Deoxycorticosterone
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KEGG COMPOUND
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21-Hydroxy-4-pregnene-3,20-dione
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KEGG COMPOUND
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21-hydroxyprogesterone
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UniProt
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21-hydroxyprogesterone
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ChemIDplus
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4-pregnen-21-ol-3,20-dione
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ChemIDplus
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Cortexone
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KEGG COMPOUND
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Deoxycorticosterone
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KEGG COMPOUND
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DESOXYCORTICOSTERONE
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PDBeChem
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Desoxycortone
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KEGG COMPOUND
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desoxycortone
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ChemIDplus
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DOC
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KEGG COMPOUND
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Kendall's desoxy compound B
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ChemIDplus
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Reichstein's substance Q
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NIST Chemistry WebBook
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2062123
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Reaxys Registry Number
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Reaxys
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64-85-7
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CAS Registry Number
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KEGG COMPOUND
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64-85-7
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CAS Registry Number
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ChemIDplus
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64-85-7
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CAS Registry Number
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NIST Chemistry WebBook
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22770225
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PubMed citation
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Europe PMC
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