CHEBI:16842 - formaldehyde

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name formaldehyde
ChEBI ID CHEBI:16842
Definition An aldehyde resulting from the formal oxidation of methanol.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:5142, CHEBI:14274, CHEBI:24077, CHEBI:337763
Supplier Information ChemicalBook:CB7459063, eMolecules:729327, ZINC000001529372
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Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins. Leucine is an α-amino acid, meaning it contains an α-amino group (which is in the protonated −NH3+ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and a side chain isobutyl group, making it a non-polar aliphatic amino acid. It is essential in humans, meaning the body cannot synthesize it; it must be obtained from the diet. Human dietary sources are foods that contain protein, such as meats, dairy products, soy products, and beans and other legumes. It is encoded by the codons UUA, UUG, CUU, CUC, CUA, and CUG. Leucine is named after the Greek word for "white": λευκός (leukós, "white"), after its common appearance as a white powder, a property it shares with many other amino acids. Like valine and isoleucine, leucine is a branched-chain amino acid. The primary metabolic end products of leucine metabolism are acetyl-CoA and acetoacetate; consequently, it is one of the two exclusively ketogenic amino acids, with lysine being the other. It is the most important ketogenic amino acid in humans. Leucine and β-hydroxy β-methylbutyric acid, a minor leucine metabolite, exhibit pharmacological activity in humans and have been demonstrated to promote protein biosynthesis via the phosphorylation of the mechanistic target of rapamycin (mTOR).
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Formula CH2O
Net Charge 0
Average Mass 30.02598
Monoisotopic Mass 30.01056
InChI InChI=1S/CH2O/c1-2/h1H2
InChIKey WSFSSNUMVMOOMR-UHFFFAOYSA-N
SMILES [H]C([H])=O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Saccharomyces cerevisiae (NCBI:txid4932) Source: yeast.sf.net See: PubMed
Escherichia coli (NCBI:txid562) See: PubMed
Homo sapiens (NCBI:txid9606) See: DOI
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Role(s): EC 3.5.1.4 (amidase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
allergen
A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
disinfectant
An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.
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ChEBI Ontology
Outgoing formaldehyde (CHEBI:16842) has role Escherichia coli metabolite (CHEBI:76971)
formaldehyde (CHEBI:16842) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
formaldehyde (CHEBI:16842) has role allergen (CHEBI:50904)
formaldehyde (CHEBI:16842) has role carcinogenic agent (CHEBI:50903)
formaldehyde (CHEBI:16842) has role disinfectant (CHEBI:48219)
formaldehyde (CHEBI:16842) has role EC 3.5.1.4 (amidase) inhibitor (CHEBI:77941)
formaldehyde (CHEBI:16842) has role environmental contaminant (CHEBI:78298)
formaldehyde (CHEBI:16842) has role mouse metabolite (CHEBI:75771)
formaldehyde (CHEBI:16842) is a aldehyde (CHEBI:17478)
formaldehyde (CHEBI:16842) is a one-carbon compound (CHEBI:64708)
Incoming compound 48/80 (CHEBI:75295) has functional parent formaldehyde (CHEBI:16842)
methanimine (CHEBI:38220) has functional parent formaldehyde (CHEBI:16842)
oxomethyl (CHEBI:29327) has functional parent formaldehyde (CHEBI:16842)
phosgene (CHEBI:29365) has functional parent formaldehyde (CHEBI:16842)
carbonylidene group (CHEBI:30152) is substituent group from formaldehyde (CHEBI:16842)
IUPAC Name
formaldehyde
Synonyms Sources
Formaldehyd NIST Chemistry WebBook
Formaldehyde KEGG COMPOUND
formaldehyde UniProt
FORMALDEHYDE PDBeChem
FORMALIN ChEMBL
Formalin KEGG COMPOUND
Methanal KEGG COMPOUND
Methylene oxide KEGG COMPOUND
Oxomethane KEGG COMPOUND
Oxomethylene KEGG COMPOUND
Manual Xrefs Databases
3244 DrugCentral
359 PPDB
C00067 KEGG COMPOUND
c0122 UM-BBD
D00017 KEGG DRUG
DB03843 DrugBank
FOR PDBeChem
Formaldehyde Wikipedia
FORMALDEHYDE MetaCyc
HMDB0001426 HMDB
View more database links
Registry Numbers Types Sources
1209228 Reaxys Registry Number Reaxys
445 Gmelin Registry Number Gmelin
50-00-0 CAS Registry Number KEGG COMPOUND
50-00-0 CAS Registry Number NIST Chemistry WebBook
50-00-0 CAS Registry Number ChemIDplus
Citations
Last Modified
20 November 2019