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| sn-glycerol 3-phosphate |
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| CHEBI:15978 |
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| sn-glycerol 3-phosphate |
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| An sn-glycerol 3-phosphate having unsubstituted hydroxy groups. |
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This entity has been manually annotated by the ChEBI Team.
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CHEBI:12848, CHEBI:42793, CHEBI:10648, CHEBI:12843, CHEBI:26705
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| ZINC000003830896 |
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Molfile
XML
SDF
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more structures >>
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call loadScript javascripts\jsmol\core\package.js call loadScript javascripts\jsmol\core\core.z.js -- required by ClazzNode call loadScript javascripts\jsmol\J\awtjs2d\WebOutputChannel.js
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| InChI=1S/C3H9O6P/c4-1-3(5)2-9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8)/t3-/m1/s1 |
| AWUCVROLDVIAJX-GSVOUGTGSA-N |
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Mus musculus
(NCBI:txid10090)
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Source: BioModels - MODEL1507180067
See:
PubMed
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Arabidopsis thaliana
(NCBI:txid3702)
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See:
DOI
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Escherichia coli
(NCBI:txid562)
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See:
PubMed
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Escherichia coli
(NCBI:txid562)
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See:
PubMed
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Homo sapiens
(NCBI:txid9606)
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See:
PubMed
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human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
(via glycerol 1-phosphate )
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
algal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
(via glycerol 1-phosphate )
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View more via ChEBI Ontology
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(2R)-2,3-dihydroxypropyl dihydrogen phosphate
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sn-glycerol 3-(dihydrogen phosphate)
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(R)-glycerol 1-phosphate
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ChEBI
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D-(glycerol 1-phosphate)
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CBN
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D-Glycerol 1-phosphate
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KEGG COMPOUND
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Glycerol-3-phosphate
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KEGG COMPOUND
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Glycerophosphoric acid
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KEGG COMPOUND
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L-(glycerol 3-phosphate)
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CBN
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phosphoric acid mono-((R)-2,3-dihydroxy-propyl) ester
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ChEBI
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Phosphorsäure-mono-((R)-2,3-dihydroxy-propylester)
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ChEBI
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sn-Glycerol 3-phosphate
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KEGG COMPOUND
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SN-GLYCEROL-3-PHOSPHATE
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PDBeChem
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sn-Gro-1-P
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KEGG COMPOUND
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1723975
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Reaxys Registry Number
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Reaxys
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17989-41-2
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CAS Registry Number
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KEGG COMPOUND
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Taleux N, Guigas B, Dubouchaud H, Moreno M, Weitzel JM, Goglia F, Favier R, Leverve XM (2009)
High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity.
The Journal of biological chemistry 284, 4308-4316 [PubMed:19049970]
[show Abstract]
Besides its well recognized role in lipid and carbohydrate metabolisms, glycerol is involved in the regulation of cellular energy homeostasis via glycerol-3-phosphate, a key metabolite in the translocation of reducing power across the mitochondrial inner membrane with mitochondrial glycerol-3-phosphate dehydrogenase. Here, we report a high rate of gluconeogenesis from glycerol and fatty acid oxidation in hepatocytes from Lou/C, a peculiar rat strain derived from Wistar, which is resistant to age- and diet-related obesity. This feature, associated with elevated cellular respiration and cytosolic ATP/ADP and NAD(+)/NADH ratios, was linked to a high expression and activity of mitochondrial glycerol-3-phosphate dehydrogenase. Interestingly, this strain exhibited high expression and protein content of thyroid hormone receptor, whereas circulating thyroid hormone levels were slightly decreased and hepatic thyroid hormone carrier MCT-8 mRNA levels were not modified. We propose that an enhanced liver thyroid hormone receptor in Lou/C may explain its unique resistance to obesity by increasing fatty acid oxidation and lowering liver oxidative phosphorylation stoichiometry at the translocation of reducing power into mitochondria. | Levy RA, Gharavi AE, Sammaritano LR, Habina L, Lockshin MD (1990)
Fatty acid chain is a critical epitope for antiphospholipid antibody.
Journal of clinical immunology 10, 141-145 [PubMed:1694860]
[show Abstract]
To explore the role of phospholipid fatty acids in binding of antiphospholipid antibody (aPL) in ELISA, we tested aPL binding to phospholipids containing fatty acids of varying chain length and degree of saturation using direct ELISA and inhibition methods. Polyclonal IgG and IgM human aPL's bind to C18:1 phosphatidylglycerol (PG) better than to C18:0 PG or C18:2 PG. Binding is greater to C18 than to C14:0 or C16:0 PGs; aPL's do not bind to C12:0 PG. aPL binding is not inhibited by C18:1 diacylglycerol, glycerol-3-phosphate, myoinositol, or myoinositol phosphate. The fatty acid chains are critical determinants for antigen recognition and, by projection, biological activity of aPL. | Rae JJ (1934)
Glycerophosphoric acid: The glycerophosphoric acid of the naturally occurring phosphatides.
The Biochemical journal 28, 152-156 [PubMed:16745347] |
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