CHEBI:15729 - L-ornithine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name L-ornithine
ChEBI ID CHEBI:15729
ChEBI ASCII Name L-ornithine
Definition An optically active form of ornithine having L-configuration.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:6280, CHEBI:21367, CHEBI:13148
Supplier Information ChemicalBook:CB5235360, eMolecules:524685
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Gefitinib, sold under the brand name Iressa, is a medication used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR, but resistances to gefitinib can arise through other mutations. It is marketed by AstraZeneca and Teva. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.
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Formula C5H12N2O2
Net Charge 0
Average Mass 132.16106
Monoisotopic Mass 132.08988
InChI InChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
InChIKey AHLPHDHHMVZTML-BYPYZUCNSA-N
SMILES NCCC[C@H](N)C(O)=O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Chlamydomonas reinhardtii (NCBI:txid3055) See: PubMed
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): algal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
(via ornithine )
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
(via ornithine )
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
(via ornithine )
Daphnia magna metabolite
A Daphnia metabolite produced by the species Daphnia magna.
(via ornithine )
Application(s): hepatoprotective agent
Any compound that is able to prevent damage to the liver.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing L-ornithine (CHEBI:15729) has role algal metabolite (CHEBI:84735)
L-ornithine (CHEBI:15729) has role hepatoprotective agent (CHEBI:62868)
L-ornithine (CHEBI:15729) has role mouse metabolite (CHEBI:75771)
L-ornithine (CHEBI:15729) is a non-proteinogenic L-α-amino acid (CHEBI:83822)
L-ornithine (CHEBI:15729) is a ornithine (CHEBI:18257)
L-ornithine (CHEBI:15729) is conjugate acid of L-ornithinate (CHEBI:46914)
L-ornithine (CHEBI:15729) is conjugate base of L-ornithinium(1+) (CHEBI:46911)
L-ornithine (CHEBI:15729) is enantiomer of D-ornithine (CHEBI:16176)
Incoming L-Orn-D-Asp (CHEBI:144746) has functional parent L-ornithine (CHEBI:15729)
L-Orn-D-Glu (CHEBI:144747) has functional parent L-ornithine (CHEBI:15729)
L-ornithine derivative (CHEBI:21368) has functional parent L-ornithine (CHEBI:15729)
sinefungin (CHEBI:45453) has functional parent L-ornithine (CHEBI:15729)
L-ornithine-d6 (CHEBI:192081) is a L-ornithine (CHEBI:15729)
L-ornithinium(1+) (CHEBI:46911) is conjugate acid of L-ornithine (CHEBI:15729)
L-ornithinate (CHEBI:46914) is conjugate base of L-ornithine (CHEBI:15729)
D-ornithine (CHEBI:16176) is enantiomer of L-ornithine (CHEBI:15729)
N2-L-ornithino group (CHEBI:44548) is substituent group from L-ornithine (CHEBI:15729)
N5-L-ornithino group (CHEBI:46935) is substituent group from L-ornithine (CHEBI:15729)
L-ornithine residue (CHEBI:44571) is substituent group from L-ornithine (CHEBI:15729)
L-ornithyl group (CHEBI:44700) is substituent group from L-ornithine (CHEBI:15729)
IUPAC Names
(2S)-2,5-diaminopentanoic acid
L-ornithine
Synonyms Sources
(S)-2,5-Diaminopentanoate KEGG COMPOUND
(S)-2,5-Diaminopentanoic acid KEGG COMPOUND
(S)-2,5-diaminovaleric acid KEGG COMPOUND
(S)-α,δ-diaminovaleric acid HMDB
(S)-ornithine ChemIDplus
L-ornithine ChEBI
L-Ornithine KEGG COMPOUND
Manual Xrefs Databases
3401 DrugCentral
C00001384 KNApSAcK
C00077 KEGG COMPOUND
D08302 KEGG DRUG
DB00129 DrugBank
HMDB0000214 HMDB
ORN PDBeChem
Ornithine Wikipedia
ORNITHINE MetaCyc
View more database links
Registry Numbers Types Sources
1722298 Reaxys Registry Number Reaxys
327282 Gmelin Registry Number Gmelin
70-26-8 CAS Registry Number KEGG COMPOUND
70-26-8 CAS Registry Number ChemIDplus
Citations
Last Modified
04 September 2019