CHEBI:138649 - resolvin D4

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ChEBI Name resolvin D4
ChEBI ID CHEBI:138649
Definition A member of the class of resolvins that is (6E,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 5 and 17 (the 4S,5R,17S-stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Bijay
Supplier Information ZINC000065731641
Download Molfile XML SDF
Formula C22H32O5
Net Charge 0
Average Mass 376.487
Monoisotopic Mass 376.22497
InChI InChI=1S/C22H32O5/c1-2-3-11-14-19(23)15-12-9-7-5-4-6-8-10-13-16-20(24)21(25)17-18-22(26)27/h3-4,6-13,15-16,19-21,23-25H,2,5,14,17-18H2,1H3,(H,26,27)/b6-4-,9-7-,10-8+,11-3-,15-12+,16-13+/t19-,20+,21-/m0/s1
InChIKey YKPLJNOOLKUEBS-RIYRYSNMSA-N
SMILES C(C(O)=O)C[C@@H]([C@@H](/C=C/C=C/C=C\C/C=C\C=C\[C@H](C/C=C\CC)O)O)O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing resolvin D4 (CHEBI:138649) has role anti-inflammatory agent (CHEBI:67079)
resolvin D4 (CHEBI:138649) has role human xenobiotic metabolite (CHEBI:76967)
resolvin D4 (CHEBI:138649) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
resolvin D4 (CHEBI:138649) is a resolvin (CHEBI:132120)
resolvin D4 (CHEBI:138649) is a secondary allylic alcohol (CHEBI:134396)
resolvin D4 (CHEBI:138649) is a triol (CHEBI:27136)
IUPAC Name
(4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxydocosa-6,8,10,13,15,19-hexaenoic acid
Synonyms Sources
(4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxydocosahexaenoic acid ChEBI
RvD4 SUBMITTER
Citations Waiting for Citations Types Sources
15726828 PubMed citation Europe PMC
16799203 PubMed citation Europe PMC
21418190 PubMed citation Europe PMC
26462421 PubMed citation Europe PMC
26743932 PubMed citation Europe PMC
27534559 PubMed citation Europe PMC
27734186 PubMed citation Europe PMC
28765512 PubMed citation Europe PMC
Last Modified
05 March 2018