CHEBI:138179 - aspirin-triggered resolvin D1

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name aspirin-triggered resolvin D1
ChEBI ID CHEBI:138179
Definition A member of the class of resolvins that consists of docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid carrying three hydroxy substituents at positions 7, 8, and 17 (the 7S,8R,17S-stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB22589642, Selleckchem:tideglusib, ZINC000013985228
Download Molfile XML SDF
Formula C22H32O5
Net Charge 0
Average Mass 376.487
Monoisotopic Mass 376.22497
InChI InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21+/m1/s1
InChIKey OIWTWACQMDFHJG-BJEBZIPWSA-N
SMILES C(CC/C=C\C[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@@H](C/C=C\CC)O)O)O)(O)=O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): antiviral agent
A substance that destroys or inhibits replication of viruses.
analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
TGFbeta receptor antagonist
An antagonist that binds to and deactivates TGFbeta receptors.
human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
nephroprotective agent
Any protective agent that is able to prevent damage to the kidney.
anti-allergic agent
A drug used to treat allergic reactions.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing aspirin-triggered resolvin D1 (CHEBI:138179) has role analgesic (CHEBI:35480)
aspirin-triggered resolvin D1 (CHEBI:138179) has role anti-allergic agent (CHEBI:50857)
aspirin-triggered resolvin D1 (CHEBI:138179) has role anti-inflammatory agent (CHEBI:67079)
aspirin-triggered resolvin D1 (CHEBI:138179) has role antiviral agent (CHEBI:22587)
aspirin-triggered resolvin D1 (CHEBI:138179) has role human xenobiotic metabolite (CHEBI:76967)
aspirin-triggered resolvin D1 (CHEBI:138179) has role nephroprotective agent (CHEBI:76595)
aspirin-triggered resolvin D1 (CHEBI:138179) has role TGFβ receptor antagonist (CHEBI:91202)
aspirin-triggered resolvin D1 (CHEBI:138179) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
aspirin-triggered resolvin D1 (CHEBI:138179) is a resolvin (CHEBI:132120)
aspirin-triggered resolvin D1 (CHEBI:138179) is a secondary allylic alcohol (CHEBI:134396)
IUPAC Name
(4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
Synonyms Sources
(4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosahexaenoic acid ChEBI
17(R)-resolvin D1 ChEBI
17(R)-RvD1 ChEBI
17-epi-resolvin D1 ChEBI
7S,8R,17R-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid LIPID MAPS
AT-Resolvin D1 LIPID MAPS
AT-RvD1 LIPID MAPS
Manual Xref Database
LMFA04030005 LIPID MAPS
View more database links
Registry Number Type Source
24477830 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
05 March 2018