CHEBI:137038 - (18S)-resolvin E1

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ChEBI Name (18S)-resolvin E1
ChEBI ID CHEBI:137038
ChEBI ASCII Name (18S)-resolvin E1
Definition A resolvin that is (6Z,8E,10E,14Z,16E)-icosa-6,8,10,14,16-pentaenoic acid which is substituted at positions 5, 12 and 18 by hydroxy groups (the 5S,12R,18S stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Bijay
Secondary ChEBI IDs CHEBI:138498
Supplier Information ZINC000038214815
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Formulae C20H30O5
C20H30O5
Net Charge 0
Average Mass 350.450
Monoisotopic Mass 350.20932
InChI InChI=1S/C20H30O5/c1-2-17(21)11-8-5-9-14-18(22)12-6-3-4-7-13-19(23)15-10-16-20(24)25/h3-9,11-13,17-19,21-23H,2,10,14-16H2,1H3,(H,24,25)/b4-3+,9-5-,11-8+,12-6+,13-7-/t17-,18-,19+/m0/s1
InChIKey AOPOCGPBAIARAV-JJVMZPRHSA-N
SMILES C(\[C@H](CCCC(O)=O)O)=C\C=C\C=C\[C@@H](C\C=C/C=C/[C@H](CC)O)O
Metabolite of Species Details
Homo Sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (18S)-resolvin E1 (CHEBI:137038) has role anti-inflammatory agent (CHEBI:67079)
(18S)-resolvin E1 (CHEBI:137038) has role human xenobiotic metabolite (CHEBI:76967)
(18S)-resolvin E1 (CHEBI:137038) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
(18S)-resolvin E1 (CHEBI:137038) is a resolvin (CHEBI:132120)
(18S)-resolvin E1 (CHEBI:137038) is a secondary allylic alcohol (CHEBI:134396)
(18S)-resolvin E1 (CHEBI:137038) is a triol (CHEBI:27136)
(18S)-resolvin E1 (CHEBI:137038) is conjugate acid of (18S)-resolvin E1(1−) (CHEBI:136057)
Incoming (18S)-resolvin E1(1−) (CHEBI:136057) is conjugate base of (18S)-resolvin E1 (CHEBI:137038)
IUPAC Name
(5S,6Z,8E,10E,12R,14Z,16E,18S)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid
Synonyms Sources
(5S,12R,18S)-trihydroxy-(6Z,8E,10E,14Z,16E)-eicosapentaenoic acid ChEBI
(5S,12R,18S)-trihydroxy-(6Z,8E,10E,14Z,16E)-icosapentaenoic acid ChEBI
(5S,6Z,8E,10E,12R,14Z,16E,18S)-5,12,18-trihydroxyicosapentaenoic acid ChEBI
18S-resolvin E1 ChEBI
18S-RvE1 ChEBI
5S,12R,18S-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid LIPID MAPS
Manual Xref Database
LMFA03070035 LIPID MAPS
View more database links
Citations Waiting for Citations Types Sources
21206090 PubMed citation Europe PMC
21712098 PubMed citation Europe PMC
Last Modified
05 March 2018