CHEBI:137034 - (18S)-resolvin E2

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ChEBI Name (18S)-resolvin E2
ChEBI ID CHEBI:137034
ChEBI ASCII Name (18S)-resolvin E2
Definition A member of the class of resolvins that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid carrying two hydroxy substituents at positions 5 and 18 (the 5S,18S stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ZINC000169309052
Download Molfile XML SDF
Formula C20H30O4
Net Charge 0
Average Mass 334.451
Monoisotopic Mass 334.21441
InChI InChI=1S/C20H30O4/c1-2-18(21)14-11-9-7-5-3-4-6-8-10-12-15-19(22)16-13-17-20(23)24/h3-4,7-12,14-15,18-19,21-22H,2,5-6,13,16-17H2,1H3,(H,23,24)/b4-3-,9-7-,10-8-,14-11+,15-12+/t18-,19+/m0/s1
InChIKey KPRHYAOSTOHNQA-SFHVADPASA-N
SMILES C(C[C@@H](/C=C/C=C\C/C=C\C\C=C/C=C/[C@H](CC)O)O)CC(=O)O
Metabolite of Species Details
Homo Sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (18S)-resolvin E2 (CHEBI:137034) has role anti-inflammatory agent (CHEBI:67079)
(18S)-resolvin E2 (CHEBI:137034) has role human xenobiotic metabolite (CHEBI:76967)
(18S)-resolvin E2 (CHEBI:137034) is a diol (CHEBI:23824)
(18S)-resolvin E2 (CHEBI:137034) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
(18S)-resolvin E2 (CHEBI:137034) is a resolvin (CHEBI:132120)
(18S)-resolvin E2 (CHEBI:137034) is a secondary allylic alcohol (CHEBI:134396)
(18S)-resolvin E2 (CHEBI:137034) is conjugate acid of (18S)-resolvin E2(1−) (CHEBI:136056)
Incoming (18S)-resolvin E2(1−) (CHEBI:136056) is conjugate base of (18S)-resolvin E2 (CHEBI:137034)
IUPAC Name
(5S,6E,8Z,11Z,14Z,16E,18S)-5,18-dihydroxyicosa-6,8,11,14,16-pentaenoic acid
Synonyms Sources
(5S,18S)-dihydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoic acid ChEBI
(5S,18S)-dihydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid ChEBI
(5S,6E,8Z,11Z,14Z,16E,18S)-5,18-dihydroxyicosapentaenoic acid ChEBI
18S-resolvin E2 ChEBI
18S-RvE2 ChEBI
5S,18S-dihydroxy-6E,8Z,11Z,14Z,16E-eicosapentaenoic acid LIPID MAPS
Manual Xref Database
LMFA03070036 LIPID MAPS
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Citations
Last Modified
05 March 2018