CHEBI:137034 - (18S)-resolvin E2

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ChEBI Name (18S)-resolvin E2
ChEBI ID CHEBI:137034
ChEBI ASCII Name (18S)-resolvin E2
Definition A member of the class of resolvins that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid carrying two hydroxy substituents at positions 5 and 18 (the 5S,18S stereoisomer).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ZINC000169309052
Download Molfile XML SDF
Formula C20H30O4
Net Charge 0
Average Mass 334.451
Monoisotopic Mass 334.21441
InChI InChI=1S/C20H30O4/c1-2-18(21)14-11-9-7-5-3-4-6-8-10-12-15-19(22)16-13-17-20(23)24/h3-4,7-12,14-15,18-19,21-22H,2,5-6,13,16-17H2,1H3,(H,23,24)/b4-3-,9-7-,10-8-,14-11+,15-12+/t18-,19+/m0/s1
InChIKey KPRHYAOSTOHNQA-SFHVADPASA-N
SMILES C(C[C@@H](/C=C/C=C\C/C=C\C\C=C/C=C/[C@H](CC)O)O)CC(=O)O
Metabolite of Species Details
Homo Sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (18S)-resolvin E2 (CHEBI:137034) has role anti-inflammatory agent (CHEBI:67079)
(18S)-resolvin E2 (CHEBI:137034) has role human xenobiotic metabolite (CHEBI:76967)
(18S)-resolvin E2 (CHEBI:137034) is a diol (CHEBI:23824)
(18S)-resolvin E2 (CHEBI:137034) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
(18S)-resolvin E2 (CHEBI:137034) is a resolvin (CHEBI:132120)
(18S)-resolvin E2 (CHEBI:137034) is a secondary allylic alcohol (CHEBI:134396)
(18S)-resolvin E2 (CHEBI:137034) is conjugate acid of (18S)-resolvin E2(1−) (CHEBI:136056)
Incoming (18S)-resolvin E2(1−) (CHEBI:136056) is conjugate base of (18S)-resolvin E2 (CHEBI:137034)
IUPAC Name
(5S,6E,8Z,11Z,14Z,16E,18S)-5,18-dihydroxyicosa-6,8,11,14,16-pentaenoic acid
Synonyms Sources
(5S,18S)-dihydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoic acid ChEBI
(5S,18S)-dihydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid ChEBI
(5S,6E,8Z,11Z,14Z,16E,18S)-5,18-dihydroxyicosapentaenoic acid ChEBI
18S-resolvin E2 ChEBI
18S-RvE2 ChEBI
5S,18S-dihydroxy-6E,8Z,11Z,14Z,16E-eicosapentaenoic acid LIPID MAPS
Manual Xref Database
LMFA03070036 LIPID MAPS
View more database links
Citations Waiting for Citations Types Sources
21206090 PubMed citation Europe PMC
21712098 PubMed citation Europe PMC
Last Modified
05 March 2018